Gene name: ERG5
Reference locus (S288C): YMR015C
Gene biotype: protein_coding
Description: Cytochrome P450 61; C-22 sterol desaturase; a cytochrome P450 enzyme that catalyzes the formation of the C-22(23) double bond in the sterol side chain in ergosterol biosynthesis; may be a target of azole antifungal drugs
Top 10 interactors (score): ERG6 (0.999); ERG1 (0.999); ERG4 (0.999); ERG3 (0.999); ERG25 (0.999); ERG7 (0.997); ERG2 (0.995); ERG27 (0.986); ERG24 (0.974); ERG13 (0.967); ERG10 (0.959); CYB5 (0.944); ERG26 (0.937); ERG28 (0.923); ERG9 (0.911); OLE1 (0.888); HEM13 (0.888); HMG1 (0.879); ERG8 (0.86); ERG12 (0.857)
Homologues (species, bitscore): CYP26A1 (Homo sapiens, 95.1); Cyp3a57 (Mus musculus, 102.8); cyp26a1 (Danio rerio, 111.3); Cyp3a4.2 (Xenopus tropicalis, 109.0); Cyp4d8 (Drosophila melanogaster, 111.3); cyp-25A1 (Caenorhabditis elegans, 92.8); CYP710A4 (Arabidopsis thaliana, 196.8)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005307.1:350493-352109:- | gene-YMR015C_AKU4011 | rna-NM_001182511.1_AKU4011 | cds-NP_013728.1_AKU4011 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000201.1:190762-192378:+ | gene-YMR015C_BG1 | rna-NM_001182511.1_BG1 | cds-NP_013728.1_BG1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005515.1:290436-292052:- | gene-YMR015C_Bruggeman | rna-NM_001182511.1_Bruggeman | cds-NP_013728.1_Bruggeman | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005531.1:292929-294545:- | gene-YMR015C_CAT1 | rna-NM_001182511.1_CAT1 | cds-NP_013728.1_CAT1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005371.1:283434-285050:- | gene-YMR015C_CBS1585 | rna-NM_001182511.1_CBS1585 | cds-NP_013728.1_CBS1585 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005355.1:288957-290573:- | gene-YMR015C_CBS436 | rna-NM_001182511.1_CBS436 | cds-NP_013728.1_CBS436 | 99.9 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005339.1:396838-398454:- | gene-YMR015C_CBS6412 | rna-NM_001182511.1_CBS6412 | cds-NP_013728.1_CBS6412 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005323.1:282690-284306:- | gene-YMR015C_CBS6413 | rna-NM_001182511.1_CBS6413 | cds-NP_013728.1_CBS6413 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001534.1:295600-297216:- | gene-YMR015C_CENPK1137D | rna-NM_001182511.1_CENPK1137D | cds-NP_013728.1_CENPK1137D | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005483.1:283241-284857:- | gene-YMR015C_EthanolRed | rna-NM_001182511.1_EthanolRed | cds-NP_013728.1_EthanolRed | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005547.1:286424-288040:- | gene-YMR015C_FaliES1 | rna-NM_001182511.1_FaliES1 | cds-NP_013728.1_FaliES1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000033.1:148893-150509:+ | gene-YMR015C_JAY291 | rna-NM_001182511.1_JAY291 | cds-NP_013728.1_JAY291 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005419.1:288147-289763:- | gene-YMR015C_MUCL30387 | rna-NM_001182511.1_MUCL30387 | cds-NP_013728.1_MUCL30387 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005451.1:292821-294437:- | gene-YMR015C_MUCL30388 | rna-NM_001182511.1_MUCL30388 | cds-NP_013728.1_MUCL30388 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005291.1:283719-285335:- | gene-YMR015C_MUCL39482 | rna-NM_001182511.1_MUCL39482 | cds-NP_013728.1_MUCL39482 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005435.1:289504-291120:- | gene-YMR015C_MUCL42920 | rna-NM_001182511.1_MUCL42920 | cds-NP_013728.1_MUCL42920 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011822.1:300823-302439:- | gene-YMR015C_NCIM3186 | rna-NM_001182511.1_NCIM3186 | cds-NP_013728.1_NCIM3186 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005275.1:283636-285252:- | gene-YMR015C_NCYC1407 | rna-NM_001182511.1_NCYC1407 | cds-NP_013728.1_NCYC1407 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994152.1:289563-291179:- | gene-YMR015C_PE2H3 | rna-NM_001182511.1_PE2H3 | cds-NP_013728.1_PE2H3 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999884.1:295658-297274:- | gene-YMR015C_PE2H4 | rna-NM_001182511.1_PE2H4 | cds-NP_013728.1_PE2H4 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001145.3:300869-302485:- | gene-YMR015C_S288C | rna-NM_001182511.1_S288C | cds-NP_013728.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000005.1:235781-237397:+ | gene-YMR015C_SA1 | rna-NM_001182511.1_SA1 | cds-NP_013728.1_SA1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005499.1:283493-285109:- | gene-YMR015C_ThermosaccDry | rna-NM_001182511.1_ThermosaccDry | cds-NP_013728.1_ThermosaccDry | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005467.1:287447-289063:- | gene-YMR015C_VR1 | rna-NM_001182511.1_VR1 | cds-NP_013728.1_VR1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000027.1:262540-264156:- | gene-YMR015C_ZTW1 | rna-NM_001182511.1_ZTW1 | cds-NP_013728.1_ZTW1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047499.1:296384-298000:- | gene-YMR015C_Sparadoxus | rna-NM_001182511.1_Sparadoxus | cds-NP_013728.1_Sparadoxus | 93.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |