Gene name: ERG24
Reference locus (S288C): YNL280C
Gene biotype: protein_coding
Description: C-14 sterol reductase; acts in ergosterol biosynthesis; mutants accumulate the abnormal sterol ignosterol (ergosta-8,14 dienol), and are viable under anaerobic growth conditions but inviable on rich medium under aerobic conditions; Belongs to the ERG4/ERG24 family
Top 10 interactors (score): ERG11 (0.999); ERG28 (0.999); ERG6 (0.999); ERG3 (0.999); ERG2 (0.999); ERG1 (0.998); ERG26 (0.998); ERG27 (0.997); ERG25 (0.997); ERG9 (0.992); ERG7 (0.987); ERG5 (0.974); ERG4 (0.97); ERG13 (0.923); ERG20 (0.921); ERG10 (0.919); ERG8 (0.894); KAP95 (0.888); ERG12 (0.858); MVD1 (0.83)
Homologues (species, bitscore): LBR (Homo sapiens, 292.4); Lbr (Mus musculus, 312.0); tm7sf2 (Danio rerio, 305.8); tm7sf2 (Xenopus tropicalis, 292.4); LBR (Drosophila melanogaster, 85.9); dhcr-7 (Caenorhabditis elegans, 103.2); FK (Arabidopsis thaliana, 211.8)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005308.1:102902-104218:- | gene-YNL280C_AKU4011 | rna-NM_001183118.1_AKU4011 | cds-NP_014119.1_AKU4011 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000155.1:6774-8090:- | gene-YNL280C_BG1 | rna-NM_001183118.1_BG1 | cds-NP_014119.1_BG1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005516.1:112690-114006:- | gene-YNL280C_Bruggeman | rna-NM_001183118.1_Bruggeman | cds-NP_014119.1_Bruggeman | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005532.1:115947-117263:- | gene-YNL280C_CAT1 | rna-NM_001183118.1_CAT1 | cds-NP_014119.1_CAT1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005372.1:103292-104608:- | gene-YNL280C_CBS1585 | rna-NM_001183118.1_CBS1585 | cds-NP_014119.1_CBS1585 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005356.1:98371-99687:- | gene-YNL280C_CBS436 | rna-NM_001183118.1_CBS436 | cds-NP_014119.1_CBS436 | 99.7 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005340.1:99712-101028:- | gene-YNL280C_CBS6412 | rna-NM_001183118.1_CBS6412 | cds-NP_014119.1_CBS6412 | 99.5 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005324.1:99995-101311:- | gene-YNL280C_CBS6413 | rna-NM_001183118.1_CBS6413 | cds-NP_014119.1_CBS6413 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001535.1:102927-104243:- | gene-YNL280C_CENPK1137D | rna-NM_001183118.1_CENPK1137D | cds-NP_014119.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005484.1:100519-101835:- | gene-YNL280C_EthanolRed | rna-NM_001183118.1_EthanolRed | cds-NP_014119.1_EthanolRed | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005548.1:95256-96572:- | gene-YNL280C_FaliES1 | rna-NM_001183118.1_FaliES1 | cds-NP_014119.1_FaliES1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000082.1:6480-7796:- | gene-YNL280C_JAY291 | rna-NM_001183118.1_JAY291 | cds-NP_014119.1_JAY291 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005420.1:107739-109055:- | gene-YNL280C_MUCL30387 | rna-NM_001183118.1_MUCL30387 | cds-NP_014119.1_MUCL30387 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005452.1:106292-107608:- | gene-YNL280C_MUCL30388 | rna-NM_001183118.1_MUCL30388 | cds-NP_014119.1_MUCL30388 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005292.1:100782-102098:- | gene-YNL280C_MUCL39482 | rna-NM_001183118.1_MUCL39482 | cds-NP_014119.1_MUCL39482 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005436.1:103032-104348:- | gene-YNL280C_MUCL42920 | rna-NM_001183118.1_MUCL42920 | cds-NP_014119.1_MUCL42920 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011823.1:109064-110380:- | gene-YNL280C_NCIM3186 | rna-NM_001183118.1_NCIM3186 | cds-NP_014119.1_NCIM3186 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005276.1:102649-103965:- | gene-YNL280C_NCYC1407 | rna-NM_001183118.1_NCYC1407 | cds-NP_014119.1_NCYC1407 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994153.1:99816-101132:- | gene-YNL280C_PE2H3 | rna-NM_001183118.1_PE2H3 | cds-NP_014119.1_PE2H3 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999885.1:99204-100520:- | gene-YNL280C_PE2H4 | rna-NM_001183118.1_PE2H4 | cds-NP_014119.1_PE2H4 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001146.8:109095-110411:- | gene-YNL280C_S288C | rna-NM_001183118.1_S288C | cds-NP_014119.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000034.1:6547-7863:- | gene-YNL280C_SA1 | rna-NM_001183118.1_SA1 | cds-NP_014119.1_SA1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005500.1:96113-97429:- | gene-YNL280C_ThermosaccDry | rna-NM_001183118.1_ThermosaccDry | cds-NP_014119.1_ThermosaccDry | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005468.1:115014-116330:- | gene-YNL280C_VR1 | rna-NM_001183118.1_VR1 | cds-NP_014119.1_VR1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000030.1:6481-7797:- | gene-YNL280C_ZTW1 | rna-NM_001183118.1_ZTW1 | cds-NP_014119.1_ZTW1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047500.1:106384-107700:- | gene-YNL280C_Sparadoxus | rna-NM_001183118.1_Sparadoxus | cds-NP_014119.1_Sparadoxus | 92.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |