Gene name: ERG2
Reference locus (S288C): YMR202W
Gene biotype: protein_coding
Description: C-8 sterol isomerase; catalyzes isomerization of delta-8 double bond to delta-7 position at an intermediate step in ergosterol biosynthesis; transcriptionally down-regulated when ergosterol is in excess; mutation is functionally complemented by human EBP
Top 10 interactors (score): ERG25 (0.999); ERG24 (0.999); ERG6 (0.999); ERG28 (0.999); ERG11 (0.999); ERG3 (0.999); ERG1 (0.999); ERG4 (0.996); ERG26 (0.996); ERG5 (0.995); ERG7 (0.96); UPC2 (0.96); ERG9 (0.947); ERG13 (0.93); KAR2 (0.928); ERG27 (0.917); ECM22 (0.871); ERG10 (0.87); ELO3 (0.863); ERG8 (0.838)
Homologues (species, bitscore): SIGMAR1 (Homo sapiens, 95.1); Sigmar1 (Mus musculus, 96.3); sigmar1 (Danio rerio, 98.2); ENSXETP00000028907 (Xenopus tropicalis, 100.5)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005307.1:707447-708115:+ | gene-YMR202W_AKU4011 | rna-NM_001182709.1_AKU4011 | cds-NP_013929.1_AKU4011 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000069.1:246468-247136:- | gene-YMR202W_BG1 | rna-NM_001182709.1_BG1 | cds-NP_013929.1_BG1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005515.1:651673-652341:+ | gene-YMR202W_Bruggeman | rna-NM_001182709.1_Bruggeman | cds-NP_013929.1_Bruggeman | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005531.1:654927-655595:+ | gene-YMR202W_CAT1 | rna-NM_001182709.1_CAT1 | cds-NP_013929.1_CAT1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005371.1:639704-640372:+ | gene-YMR202W_CBS1585 | rna-NM_001182709.1_CBS1585 | cds-NP_013929.1_CBS1585 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005355.1:643971-644639:+ | gene-YMR202W_CBS436 | rna-NM_001182709.1_CBS436 | cds-NP_013929.1_CBS436 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005339.1:751261-751929:+ | gene-YMR202W_CBS6412 | rna-NM_001182709.1_CBS6412 | cds-NP_013929.1_CBS6412 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005323.1:638853-639521:+ | gene-YMR202W_CBS6413 | rna-NM_001182709.1_CBS6413 | cds-NP_013929.1_CBS6413 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001534.1:662223-662891:+ | gene-YMR202W_CENPK1137D | rna-NM_001182709.1_CENPK1137D | cds-NP_013929.1_CENPK1137D | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005486.1:699894-700562:+ | gene-YMR202W_EthanolRed | rna-NM_001182709.1_EthanolRed | cds-NP_013929.1_EthanolRed | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005547.1:645548-646216:+ | gene-YMR202W_FaliES1 | rna-NM_001182709.1_FaliES1 | cds-NP_013929.1_FaliES1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000141.1:139786-140454:- | gene-YMR202W_JAY291 | rna-NM_001182709.1_JAY291 | cds-NP_013929.1_JAY291 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005419.1:645220-645888:+ | gene-YMR202W_MUCL30387 | rna-NM_001182709.1_MUCL30387 | cds-NP_013929.1_MUCL30387 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005451.1:651996-652664:+ | gene-YMR202W_MUCL30388 | rna-NM_001182709.1_MUCL30388 | cds-NP_013929.1_MUCL30388 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005291.1:640774-641442:+ | gene-YMR202W_MUCL39482 | rna-NM_001182709.1_MUCL39482 | cds-NP_013929.1_MUCL39482 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005435.1:648115-648783:+ | gene-YMR202W_MUCL42920 | rna-NM_001182709.1_MUCL42920 | cds-NP_013929.1_MUCL42920 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011822.1:667491-668159:+ | gene-YMR202W_NCIM3186 | rna-NM_001182709.1_NCIM3186 | cds-NP_013929.1_NCIM3186 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005275.1:640426-641094:+ | gene-YMR202W_NCYC1407 | rna-NM_001182709.1_NCYC1407 | cds-NP_013929.1_NCYC1407 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994152.1:650286-650954:+ | gene-YMR202W_PE2H3 | rna-NM_001182709.1_PE2H3 | cds-NP_013929.1_PE2H3 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999884.1:651303-651971:+ | gene-YMR202W_PE2H4 | rna-NM_001182709.1_PE2H4 | cds-NP_013929.1_PE2H4 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001145.3:667537-668205:+ | gene-YMR202W_S288C | rna-NM_001182709.1_S288C | cds-NP_013929.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000002.1:139908-140576:- | gene-YMR202W_SA1 | rna-NM_001182709.1_SA1 | cds-NP_013929.1_SA1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005499.1:641676-642344:+ | gene-YMR202W_ThermosaccDry | rna-NM_001182709.1_ThermosaccDry | cds-NP_013929.1_ThermosaccDry | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005467.1:654818-655486:+ | gene-YMR202W_VR1 | rna-NM_001182709.1_VR1 | cds-NP_013929.1_VR1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000028.1:57451-58119:+ | gene-YMR202W_ZTW1 | rna-NM_001182709.1_ZTW1 | cds-NP_013929.1_ZTW1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047499.1:659590-660258:+ | gene-YMR202W_Sparadoxus | rna-NM_001182709.1_Sparadoxus | cds-NP_013929.1_Sparadoxus | 92.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |