ERF2 (YLR246W)


Gene profile

Gene name: ERF2
Reference locus (S288C): YLR246W
Gene biotype: protein_coding

Description: Subunit of a palmitoyltransferase; this complex adds a palmitoyl lipid moiety to heterolipidated substrates such as Ras1p and Ras2p through a thioester linkage; mutants partially mislocalize Ras2p to the vacuole; palmitoyltransferase is composed of Erf2p and Shr5p

Top 10 interactors (score): SHR5 (0.991); RAS2 (0.839); RAS1 (0.749); RHO2 (0.738); SAC1 (0.722); ORM1 (0.722); LCB2 (0.722); ORM2 (0.722); LCB1 (0.72); TSC3 (0.72); RHO3 (0.662); CYS4 (0.654); AKR1 (0.621); AKR2 (0.621); STE14 (0.597); TRM2 (0.565); ELF1 (0.554); RHO1 (0.545); PUT1 (0.535); MAK5 (0.509)

Homologues (species, bitscore): ZDHHC9 (Homo sapiens, 136.3); Zdhhc9 (Mus musculus, 136.7); zdhhc9 (Danio rerio, 129.4); zdhhc9 (Xenopus tropicalis, 134.0); app (Drosophila melanogaster, 133.7); dhhc-2 (Caenorhabditis elegans, 113.2); AT4G24630 (Arabidopsis thaliana, 140.6)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005306.1:581331-582410:+ gene-YLR246W_AKU4011 rna-NM_001182133.1_AKU4011 cds-NP_013347.1_AKU4011 99.4 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000170.1:149487-150566:- gene-YLR246W_BG1 rna-NM_001182133.1_BG1 cds-NP_013347.1_BG1 99.5 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005514.1:615568-616647:+ gene-YLR246W_Bruggeman rna-NM_001182133.1_Bruggeman cds-NP_013347.1_Bruggeman 99.5 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005530.1:614692-615771:+ gene-YLR246W_CAT1 rna-NM_001182133.1_CAT1 cds-NP_013347.1_CAT1 99.6 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005370.1:616826-617905:+ gene-YLR246W_CBS1585 rna-NM_001182133.1_CBS1585 cds-NP_013347.1_CBS1585 99.4 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005354.1:601033-602112:+ gene-YLR246W_CBS436 rna-NM_001182133.1_CBS436 cds-NP_013347.1_CBS436 99.5 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005338.1:579801-580880:+ gene-YLR246W_CBS6412 rna-NM_001182133.1_CBS6412 cds-NP_013347.1_CBS6412 99.4 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005322.1:617121-618200:+ gene-YLR246W_CBS6413 rna-NM_001182133.1_CBS6413 cds-NP_013347.1_CBS6413 99.4 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001533.1:611729-612808:+ gene-YLR246W_CENPK1137D rna-NM_001182133.1_CENPK1137D cds-NP_013347.1_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005482.1:574863-575942:+ gene-YLR246W_EthanolRed rna-NM_001182133.1_EthanolRed cds-NP_013347.1_EthanolRed 99.5 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005546.1:603788-604867:+ gene-YLR246W_FaliES1 rna-NM_001182133.1_FaliES1 cds-NP_013347.1_FaliES1 99.5 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000136.1:54007-55086:- gene-YLR246W_JAY291 rna-NM_001182133.1_JAY291 cds-NP_013347.1_JAY291 99.5 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005418.1:616424-617503:+ gene-YLR246W_MUCL30387 rna-NM_001182133.1_MUCL30387 cds-NP_013347.1_MUCL30387 99.5 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005450.1:620545-621624:+ gene-YLR246W_MUCL30388 rna-NM_001182133.1_MUCL30388 cds-NP_013347.1_MUCL30388 99.5 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005290.1:617807-618886:+ gene-YLR246W_MUCL39482 rna-NM_001182133.1_MUCL39482 cds-NP_013347.1_MUCL39482 99.4 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005434.1:612568-613647:+ gene-YLR246W_MUCL42920 rna-NM_001182133.1_MUCL42920 cds-NP_013347.1_MUCL42920 99.5 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011821.1:627092-628171:+ gene-YLR246W_NCIM3186 rna-NM_001182133.1_NCIM3186 cds-NP_013347.1_NCIM3186 99.5 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005274.1:604793-605872:+ gene-YLR246W_NCYC1407 rna-NM_001182133.1_NCYC1407 cds-NP_013347.1_NCYC1407 99.4 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994151.1:608524-609603:+ gene-YLR246W_PE2H3 rna-NM_001182133.1_PE2H3 cds-NP_013347.1_PE2H3 99.5 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999883.1:608268-609347:+ gene-YLR246W_PE2H4 rna-NM_001182133.1_PE2H4 cds-NP_013347.1_PE2H4 99.5 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001144.5:627118-628197:+ gene-YLR246W_S288C rna-NM_001182133.1_S288C cds-NP_013347.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000013.1:54270-55349:- gene-YLR246W_SA1 rna-NM_001182133.1_SA1 cds-NP_013347.1_SA1 99.5 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005498.1:606288-607367:+ gene-YLR246W_ThermosaccDry rna-NM_001182133.1_ThermosaccDry cds-NP_013347.1_ThermosaccDry 99.5 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005466.1:617638-618717:+ gene-YLR246W_VR1 rna-NM_001182133.1_VR1 cds-NP_013347.1_VR1 99.5 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000024.1:130602-131681:+ gene-YLR246W_ZTW1 rna-NM_001182133.1_ZTW1 cds-NP_013347.1_ZTW1 99.6 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047498.1:591791-592870:+ gene-YLR246W_Sparadoxus rna-NM_001182133.1_Sparadoxus cds-NP_013347.1_Sparadoxus 89.8 100.0 Unannotated 1 1 0 False False False True False

Additional files