EPS1 (YIL005W)


Gene profile

Gene name: EPS1
Reference locus (S288C): YIL005W
Gene biotype: protein_coding

Description: ER-retained PMA1-suppressing protein 1; ER protein with chaperone and co-chaperone activity; involved in retention of resident ER proteins; has a role in recognizing proteins targeted for ER-associated degradation (ERAD), member of the protein disulfide isomerase family

Top 10 interactors (score): EUG1 (0.979); ERO1 (0.978); MPD1 (0.955); KAR2 (0.951); MPD2 (0.936); PDI1 (0.869); CNE1 (0.867); LHS1 (0.814); PMA1 (0.761); BST1 (0.712); ATP14 (0.675); GLR1 (0.637); WBP1 (0.626); YKL077W (0.607); SRP101 (0.603); IZH3 (0.571); MNL2 (0.553); YOR012W (0.528); APS3 (0.516); SUA7 (0.512)

Homologues (species, bitscore): TMX3 (Homo sapiens, 62.0); Tmx3 (Mus musculus, 62.4); txndc5 (Danio rerio, 68.2); txndc5 (Xenopus tropicalis, 63.9); prtp (Drosophila melanogaster, 57.8); ZK973.11 (Caenorhabditis elegans, 58.2); PDIL2-2 (Arabidopsis thaliana, 57.0)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005303.1:345021-347126:+ gene-YIL005W_AKU4011 rna-NM_001179355.1_AKU4011 cds-NP_012261.1_AKU4011 99.1 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000072.1:79414-81519:- gene-YIL005W_BG1 rna-NM_001179355.1_BG1 cds-NP_012261.1_BG1 99.8 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005511.1:349546-351651:+ gene-YIL005W_Bruggeman rna-NM_001179355.1_Bruggeman cds-NP_012261.1_Bruggeman 99.9 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005527.1:336189-338294:+ gene-YIL005W_CAT1 rna-NM_001179355.1_CAT1 cds-NP_012261.1_CAT1 99.8 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005367.1:345094-347199:+ gene-YIL005W_CBS1585 rna-NM_001179355.1_CBS1585 cds-NP_012261.1_CBS1585 99.2 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005351.1:337822-339927:+ gene-YIL005W_CBS436 rna-NM_001179355.1_CBS436 cds-NP_012261.1_CBS436 99.9 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005335.1:340500-342605:+ gene-YIL005W_CBS6412 rna-NM_001179355.1_CBS6412 cds-NP_012261.1_CBS6412 99.2 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005319.1:337181-339286:+ gene-YIL005W_CBS6413 rna-NM_001179355.1_CBS6413 cds-NP_012261.1_CBS6413 99.2 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001530.1:337753-339858:+ gene-YIL005W_CENPK1137D rna-NM_001179355.1_CENPK1137D cds-NP_012261.1_CENPK1137D 99.9 100.0 Verified 1 1 1 False True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005479.1:328134-330239:+ gene-YIL005W_EthanolRed rna-NM_001179355.1_EthanolRed cds-NP_012261.1_EthanolRed 99.3 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005543.1:346380-348485:+ gene-YIL005W_FaliES1 rna-NM_001179355.1_FaliES1 cds-NP_012261.1_FaliES1 99.2 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000009.1:42996-45101:- gene-YIL005W_JAY291 rna-NM_001179355.1_JAY291 cds-NP_012261.1_JAY291 99.8 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005415.1:346718-348823:+ gene-YIL005W_MUCL30387 rna-NM_001179355.1_MUCL30387 cds-NP_012261.1_MUCL30387 99.8 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005447.1:343466-345571:+ gene-YIL005W_MUCL30388 rna-NM_001179355.1_MUCL30388 cds-NP_012261.1_MUCL30388 99.8 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005287.1:345710-347815:+ gene-YIL005W_MUCL39482 rna-NM_001179355.1_MUCL39482 cds-NP_012261.1_MUCL39482 99.2 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005431.1:349348-351453:+ gene-YIL005W_MUCL42920 rna-NM_001179355.1_MUCL42920 cds-NP_012261.1_MUCL42920 99.5 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011818.1:345692-347797:+ gene-YIL005W_NCIM3186 rna-NM_001179355.1_NCIM3186 cds-NP_012261.1_NCIM3186 99.3 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005271.1:349978-352083:+ gene-YIL005W_NCYC1407 rna-NM_001179355.1_NCYC1407 cds-NP_012261.1_NCYC1407 99.1 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994148.1:339767-341872:+ gene-YIL005W_PE2H3 rna-NM_001179355.1_PE2H3 cds-NP_012261.1_PE2H3 99.8 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999880.1:334473-336578:+ gene-YIL005W_PE2H4 rna-NM_001179355.1_PE2H4 cds-NP_012261.1_PE2H4 99.8 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001141.2:345692-347797:+ gene-YIL005W_S288C rna-NM_001179355.1_S288C cds-NP_012261.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000066.1:20518-22624:+ gene-YIL005W_SA1 rna-NM_001179355.1_SA1 cds-NP_012261.1_SA1 99.4 100.0 Verified 1 1 0 False False False True False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005495.1:344485-346590:+ gene-YIL005W_ThermosaccDry rna-NM_001179355.1_ThermosaccDry cds-NP_012261.1_ThermosaccDry 99.3 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005463.1:340328-342433:+ gene-YIL005W_VR1 rna-NM_001179355.1_VR1 cds-NP_012261.1_VR1 99.6 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000019.1:318488-320593:+ gene-YIL005W_ZTW1 rna-NM_001179355.1_ZTW1 cds-NP_012261.1_ZTW1 99.1 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047495.1:339847-341952:+ gene-YIL005W_Sparadoxus rna-NM_001179355.1_Sparadoxus cds-NP_012261.1_Sparadoxus 88.1 99.8 Verified 1 1 1 False True False False False

Additional files