Gene name: EPL1
Reference locus (S288C): YFL024C
Gene biotype: protein_coding
Description: Enhancer of polycomb-like protein 1; Subunit of NuA4, an essential histone H4/H2A acetyltransferase complex; conserved region at N-terminus is essential for interaction with the NPC (nucleosome core particle); required for autophagy; homologous to Drosophila Enhancer of Polycomb; coding sequence contains length polymorphisms in different strains
Top 10 interactors (score): ARP4 (0.999); ESA1 (0.999); EAF3 (0.999); EAF5 (0.999); TRA1 (0.999); YNG2 (0.999); SWC4 (0.999); YAF9 (0.999); EAF6 (0.999); EAF7 (0.999); EAF1 (0.996); ACT1 (0.994); SWR1 (0.988); SAS3 (0.985); SAS2 (0.984); GCN5 (0.975); AHC1 (0.954); SAS5 (0.948); HHF1 (0.937); ADA2 (0.922)
Homologues (species, bitscore): EPC2 (Homo sapiens, 89.4); Epc2 (Mus musculus, 89.4); epc2 (Danio rerio, 84.0); epc1 (Xenopus tropicalis, 58.2); E(Pc) (Drosophila melanogaster, 77.8); epc-1 (Caenorhabditis elegans, 55.8)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005300.1:84201-86699:- | gene-YFL024C_AKU4011 | rna-NM_001179942.1_AKU4011 | cds-NP_116629.1_AKU4011 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000199.1:8946-11504:+ | gene-YFL024C_BG1 | rna-NM_001179942.1_BG1 | cds-NP_116629.1_BG1 | 97.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005508.1:83067-85565:- | gene-YFL024C_Bruggeman | rna-NM_001179942.1_Bruggeman | cds-NP_116629.1_Bruggeman | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005524.1:88215-90725:- | gene-YFL024C_CAT1 | rna-NM_001179942.1_CAT1 | cds-NP_116629.1_CAT1 | 98.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005364.1:85009-87507:- | gene-YFL024C_CBS1585 | rna-NM_001179942.1_CBS1585 | cds-NP_116629.1_CBS1585 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005348.1:58514-61042:- | gene-YFL024C_CBS436 | rna-NM_001179942.1_CBS436 | cds-NP_116629.1_CBS436 | 98.1 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005332.1:84743-87241:- | gene-YFL024C_CBS6412 | rna-NM_001179942.1_CBS6412 | cds-NP_116629.1_CBS6412 | 99.9 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005316.1:87278-89776:- | gene-YFL024C_CBS6413 | rna-NM_001179942.1_CBS6413 | cds-NP_116629.1_CBS6413 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001527.1:84173-86671:- | gene-YFL024C_CENPK1137D | rna-NM_001179942.1_CENPK1137D | cds-NP_116629.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005476.1:83166-85664:- | gene-YFL024C_EthanolRed | rna-NM_001179942.1_EthanolRed | cds-NP_116629.1_EthanolRed | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005540.1:84806-87304:- | gene-YFL024C_FaliES1 | rna-NM_001179942.1_FaliES1 | cds-NP_116629.1_FaliES1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000448.1:93194-95722:- | gene-YFL024C_JAY291 | rna-NM_001179942.1_JAY291 | cds-NP_116629.1_JAY291 | 98.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005412.1:85164-87665:- | gene-YFL024C_MUCL30387 | rna-NM_001179942.1_MUCL30387 | cds-NP_116629.1_MUCL30387 | 99.1 | 100.0 | Unannotated | 1 | 1 | 0 | False | False | False | False | True |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005444.1:83101-85599:- | gene-YFL024C_MUCL30388 | rna-NM_001179942.1_MUCL30388 | cds-NP_116629.1_MUCL30388 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005284.1:83394-85892:- | gene-YFL024C_MUCL39482 | rna-NM_001179942.1_MUCL39482 | cds-NP_116629.1_MUCL39482 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005428.1:81504-84032:- | gene-YFL024C_MUCL42920 | rna-NM_001179942.1_MUCL42920 | cds-NP_116629.1_MUCL42920 | 98.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011815.1:87846-90344:- | gene-YFL024C_NCIM3186 | rna-NM_001179942.1_NCIM3186 | cds-NP_116629.1_NCIM3186 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005268.1:84483-86981:- | gene-YFL024C_NCYC1407 | rna-NM_001179942.1_NCYC1407 | cds-NP_116629.1_NCYC1407 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994145.1:104386-106914:- | gene-YFL024C_PE2H3 | rna-NM_001179942.1_PE2H3 | cds-NP_116629.1_PE2H3 | 98.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999877.1:103937-106465:- | gene-YFL024C_PE2H4 | rna-NM_001179942.1_PE2H4 | cds-NP_116629.1_PE2H4 | 98.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001138.5:87847-90345:- | gene-YFL024C_S288C | rna-NM_001179942.1_S288C | cds-NP_116629.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000105.1:433-2991:- | gene-YFL024C_SA1 | rna-NM_001179942.1_SA1 | cds-NP_116629.1_SA1 | 96.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005492.1:83988-86486:- | gene-YFL024C_ThermosaccDry | rna-NM_001179942.1_ThermosaccDry | cds-NP_116629.1_ThermosaccDry | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005460.1:93015-95516:- | gene-YFL024C_VR1 | rna-NM_001179942.1_VR1 | cds-NP_116629.1_VR1 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000013.1:14459-16957:- | gene-YFL024C_ZTW1 | rna-NM_001179942.1_ZTW1 | cds-NP_116629.1_ZTW1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047492.1:108239-110752:- | gene-YFL024C_Sparadoxus | rna-NM_001179942.1_Sparadoxus | cds-NP_116629.1_Sparadoxus | 90.9 | 99.8 | Verified | 1 | 1 | 1 | False | True | False | False | False |