Gene name: ENO1
Reference locus (S288C): YGR254W
Gene biotype: protein_coding
Description: Enolase I, a phosphopyruvate hydratase; catalyzes conversion of 2-phosphoglycerate to phosphoenolpyruvate during glycolysis and the reverse reaction during gluconeogenesis; expression repressed in response to glucose; protein abundance increases in response to DNA replication stress; N-terminally propionylated in vivo; ENO1 has a paralog, ENO2, that arose from the whole genome duplication
Top 10 interactors (score): GPM1 (0.999); CDC19 (0.999); ENO2 (0.999); FBA1 (0.999); PGK1 (0.999); PGI1 (0.998); TPI1 (0.997); TDH2 (0.996); TDH1 (0.996); TDH3 (0.996); PYK2 (0.994); ADH1 (0.984); YOR283W (0.981); GPM2 (0.976); PDC1 (0.975); TKL1 (0.963); TAL1 (0.961); PCK1 (0.957); GPM3 (0.948); PFK1 (0.941)
Homologues (species, bitscore): ENO3 (Homo sapiens, 577.8); Eno3 (Mus musculus, 571.2); eno1b (Danio rerio, 582.4); eno1 (Xenopus tropicalis, 573.9); Eno (Drosophila melanogaster, 587.8); enol-1 (Caenorhabditis elegans, 602.8); ENO1 (Arabidopsis thaliana, 545.8)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005301.1:966356-967669:+ | gene-YGR254W_AKU4011 | rna-NM_001181383.3_AKU4011 | cds-NP_011770.3_AKU4011 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000021.1:246525-247838:+ | gene-YGR254W_BG1 | rna-NM_001181383.3_BG1 | cds-NP_011770.3_BG1 | 99.6 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005509.1:974873-976186:+ | gene-YGR254W_Bruggeman | rna-NM_001181383.3_Bruggeman | cds-NP_011770.3_Bruggeman | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005525.1:973810-975123:+ | gene-YGR254W_CAT1 | rna-NM_001181383.3_CAT1 | cds-NP_011770.3_CAT1 | 99.3 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005365.1:969226-970539:+ | gene-YGR254W_CBS1585 | rna-NM_001181383.3_CBS1585 | cds-NP_011770.3_CBS1585 | 99.7 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005349.1:972855-974168:+ | gene-YGR254W_CBS436 | rna-NM_001181383.3_CBS436 | cds-NP_011770.3_CBS436 | 99.9 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005333.1:960116-961429:+ | gene-YGR254W_CBS6412 | rna-NM_001181383.3_CBS6412 | cds-NP_011770.3_CBS6412 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005317.1:966171-967484:+ | gene-YGR254W_CBS6413 | rna-NM_001181383.3_CBS6413 | cds-NP_011770.3_CBS6413 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001528.1:1000608-1001921:+ | gene-YGR254W_CENPK1137D | rna-NM_001181383.3_CENPK1137D | cds-NP_011770.3_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005477.1:954207-955520:+ | gene-YGR254W_EthanolRed | rna-NM_001181383.3_EthanolRed | cds-NP_011770.3_EthanolRed | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005541.1:959013-960326:+ | gene-YGR254W_FaliES1 | rna-NM_001181383.3_FaliES1 | cds-NP_011770.3_FaliES1 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000076.1:69986-71300:- | gene-YGR254W_JAY291 | rna-NM_001181383.3_JAY291 | cds-NP_011770.3_JAY291 | 99.3 | 100.0 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005413.1:972610-973923:+ | gene-YGR254W_MUCL30387 | rna-NM_001181383.3_MUCL30387 | cds-NP_011770.3_MUCL30387 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005445.1:970742-972055:+ | gene-YGR254W_MUCL30388 | rna-NM_001181383.3_MUCL30388 | cds-NP_011770.3_MUCL30388 | 99.7 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005285.1:964332-965645:+ | gene-YGR254W_MUCL39482 | rna-NM_001181383.3_MUCL39482 | cds-NP_011770.3_MUCL39482 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005429.1:982206-983519:+ | gene-YGR254W_MUCL42920 | rna-NM_001181383.3_MUCL42920 | cds-NP_011770.3_MUCL42920 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011816.1:1000927-1002240:+ | gene-YGR254W_NCIM3186 | rna-NM_001181383.3_NCIM3186 | cds-NP_011770.3_NCIM3186 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005269.1:959961-961274:+ | gene-YGR254W_NCYC1407 | rna-NM_001181383.3_NCYC1407 | cds-NP_011770.3_NCYC1407 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994146.1:985150-986463:+ | gene-YGR254W_PE2H3 | rna-NM_001181383.3_PE2H3 | cds-NP_011770.3_PE2H3 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999878.1:989989-991302:+ | gene-YGR254W_PE2H4 | rna-NM_001181383.3_PE2H4 | cds-NP_011770.3_PE2H4 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001139.9:1000927-1002240:+ | gene-YGR254W_S288C | rna-NM_001181383.3_S288C | cds-NP_011770.3_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000045.1:1-490:- | gene-YGR254W_SA1 | rna-NM_001181383.3_SA1 | cds-NP_011770.3_SA1 | 37.1 | 37.2 | Verified | 1 | 1 | 0 | False | False | False | True | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005493.1:979533-980846:+ | gene-YGR254W_ThermosaccDry | rna-NM_001181383.3_ThermosaccDry | cds-NP_011770.3_ThermosaccDry | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005461.1:1085311-1086624:+ | gene-YGR254W_VR1 | rna-NM_001181383.3_VR1 | cds-NP_011770.3_VR1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000016.1:280945-282258:+ | gene-YGR254W_ZTW1 | rna-NM_001181383.3_ZTW1 | cds-NP_011770.3_ZTW1 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047493.1:971484-972797:+ | gene-YGR254W_Sparadoxus | rna-NM_001181383.3_Sparadoxus | cds-NP_011770.3_Sparadoxus | 98.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |