Gene name: EMI2
Reference locus (S288C): YDR516C
Gene biotype: protein_coding
Description: Putative glucokinase-2; Non-essential protein of unknown function; required for transcriptional induction of the early meiotic-specific transcription factor IME1; required for sporulation; expression regulated by glucose-repression transcription factors Mig1/2p; EMI2 has a paralog, GLK1, that arose from the whole genome duplication; protein abundance increases in response to DNA replication stress
Top 10 interactors (score): GLK1 (0.994); HXK1 (0.988); PGM2 (0.985); PGI1 (0.964); GSY1 (0.954); NTH1 (0.948); FBP1 (0.944); PMI40 (0.944); NTH2 (0.938); GNA1 (0.933); GLC3 (0.928); SUC2 (0.927); RGI1 (0.923); PNC1 (0.922); PFK2 (0.917); ZWF1 (0.917); GSY2 (0.915); GAL10 (0.908); SGA1 (0.907); STF2 (0.906)
Homologues (species, bitscore): HKDC1 (Homo sapiens, 238.8); Hk1 (Mus musculus, 227.6); hk1 (Danio rerio, 229.9); Hkdc1 (Xenopus tropicalis, 233.0); Hex-t2 (Drosophila melanogaster, 216.9); F14B4.2 (Caenorhabditis elegans, 234.2); HXK3 (Arabidopsis thaliana, 230.3)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005298.1:1414985-1416487:- | gene-YDR516C_AKU4011 | rna-NM_001180824.3_AKU4011 | cds-NP_010804.3_AKU4011 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000073.1:56637-58139:- | gene-YDR516C_BG1 | rna-NM_001180824.3_BG1 | cds-NP_010804.3_BG1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005506.1:1446299-1447801:- | gene-YDR516C_Bruggeman | rna-NM_001180824.3_Bruggeman | cds-NP_010804.3_Bruggeman | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005522.1:1423478-1424980:- | gene-YDR516C_CAT1 | rna-NM_001180824.3_CAT1 | cds-NP_010804.3_CAT1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005362.1:1409711-1411213:- | gene-YDR516C_CBS1585 | rna-NM_001180824.3_CBS1585 | cds-NP_010804.3_CBS1585 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005346.1:1428953-1430455:- | gene-YDR516C_CBS436 | rna-NM_001180824.3_CBS436 | cds-NP_010804.3_CBS436 | 99.6 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005330.1:1404870-1406372:- | gene-YDR516C_CBS6412 | rna-NM_001180824.3_CBS6412 | cds-NP_010804.3_CBS6412 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005314.1:1428373-1429875:- | gene-YDR516C_CBS6413 | rna-NM_001180824.3_CBS6413 | cds-NP_010804.3_CBS6413 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001525.1:1473664-1475166:- | gene-YDR516C_CENPK1137D | rna-NM_001180824.3_CENPK1137D | cds-NP_010804.3_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005474.1:1418250-1419752:- | gene-YDR516C_EthanolRed | rna-NM_001180824.3_EthanolRed | cds-NP_010804.3_EthanolRed | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005538.1:1421802-1423304:- | gene-YDR516C_FaliES1 | rna-NM_001180824.3_FaliES1 | cds-NP_010804.3_FaliES1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000026.1:120179-121681:- | gene-YDR516C_JAY291 | rna-NM_001180824.3_JAY291 | cds-NP_010804.3_JAY291 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005410.1:1429397-1430899:- | gene-YDR516C_MUCL30387 | rna-NM_001180824.3_MUCL30387 | cds-NP_010804.3_MUCL30387 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005442.1:1410823-1412325:- | gene-YDR516C_MUCL30388 | rna-NM_001180824.3_MUCL30388 | cds-NP_010804.3_MUCL30388 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005282.1:1401209-1402711:- | gene-YDR516C_MUCL39482 | rna-NM_001180824.3_MUCL39482 | cds-NP_010804.3_MUCL39482 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005426.1:1343876-1345378:- | gene-YDR516C_MUCL42920 | rna-NM_001180824.3_MUCL42920 | cds-NP_010804.3_MUCL42920 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011813.1:1474897-1476399:- | gene-YDR516C_NCIM3186 | rna-NM_001180824.3_NCIM3186 | cds-NP_010804.3_NCIM3186 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005266.1:1414501-1416003:- | gene-YDR516C_NCYC1407 | rna-NM_001180824.3_NCYC1407 | cds-NP_010804.3_NCYC1407 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994143.1:1425448-1426950:- | gene-YDR516C_PE2H3 | rna-NM_001180824.3_PE2H3 | cds-NP_010804.3_PE2H3 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999875.1:1430916-1432418:- | gene-YDR516C_PE2H4 | rna-NM_001180824.3_PE2H4 | cds-NP_010804.3_PE2H4 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001136.10:1474974-1476476:- | gene-YDR516C_S288C | rna-NM_001180824.3_S288C | cds-NP_010804.3_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000004.1:140639-142141:+ | gene-YDR516C_SA1 | rna-NM_001180824.3_SA1 | cds-NP_010804.3_SA1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005490.1:1426024-1427526:- | gene-YDR516C_ThermosaccDry | rna-NM_001180824.3_ThermosaccDry | cds-NP_010804.3_ThermosaccDry | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005458.1:1441818-1443320:- | gene-YDR516C_VR1 | rna-NM_001180824.3_VR1 | cds-NP_010804.3_VR1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000008.1:468689-470191:- | gene-YDR516C_ZTW1 | rna-NM_001180824.3_ZTW1 | cds-NP_010804.3_ZTW1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047490.1:1434969-1436471:- | gene-YDR516C_Sparadoxus | rna-NM_001180824.3_Sparadoxus | cds-NP_010804.3_Sparadoxus | 92.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |