Gene name: EMG1
Reference locus (S288C): YLR186W
Gene biotype: protein_coding
Description: Ribosomal RNA small subunit methyltransferase NEP1; Methyltransferase for rRNA; methylates pseudouridine 18S rRNA residue 1191; member of the SPOUT methyltransferase family; required for maturation of 18S rRNA and for 40S ribosomal subunit production independent of methyltransferase activity; forms homodimers; human ortholog is mutated in Bowen-Conradi syndrome, and equivalent yeast mutation affects Emg1p dimerization and localization but not methyltransferase activity; human EMG1 complements lethality of null and ts mutant; Belongs to the class IV-like SAM-binding methyltransferase su [...]
Top 10 interactors (score): DIP2 (0.999); RRP9 (0.999); UTP30 (0.999); PWP2 (0.999); NOP58 (0.999); RCL1 (0.999); UTP18 (0.999); IMP4 (0.999); NOP1 (0.999); PNO1 (0.999); IMP3 (0.999); UTP5 (0.999); YTM1 (0.999); UTP13 (0.999); NAN1 (0.999); NOP56 (0.999); UTP15 (0.999); RRP5 (0.999); UTP11 (0.999); BMS1 (0.999)
Homologues (species, bitscore): EMG1 (Homo sapiens, 234.6); Emg1 (Mus musculus, 221.5); EMG1 (Danio rerio, 221.5); emg1 (Xenopus tropicalis, 219.2); CG3527 (Drosophila melanogaster, 222.2); Y39A1A.14 (Caenorhabditis elegans, 209.1); AT3G57000 (Arabidopsis thaliana, 203.4)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005306.1:477752-478510:+ | gene-YLR186W_AKU4011 | rna-NM_001182073.1_AKU4011 | cds-NP_013287.1_AKU4011 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000177.1:34951-35709:+ | gene-YLR186W_BG1 | rna-NM_001182073.1_BG1 | cds-NP_013287.1_BG1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005514.1:518001-518759:+ | gene-YLR186W_Bruggeman | rna-NM_001182073.1_Bruggeman | cds-NP_013287.1_Bruggeman | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005530.1:517595-518353:+ | gene-YLR186W_CAT1 | rna-NM_001182073.1_CAT1 | cds-NP_013287.1_CAT1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005370.1:513249-514007:+ | gene-YLR186W_CBS1585 | rna-NM_001182073.1_CBS1585 | cds-NP_013287.1_CBS1585 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005354.1:503387-504145:+ | gene-YLR186W_CBS436 | rna-NM_001182073.1_CBS436 | cds-NP_013287.1_CBS436 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005338.1:481806-482564:+ | gene-YLR186W_CBS6412 | rna-NM_001182073.1_CBS6412 | cds-NP_013287.1_CBS6412 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005322.1:513541-514299:+ | gene-YLR186W_CBS6413 | rna-NM_001182073.1_CBS6413 | cds-NP_013287.1_CBS6413 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001533.1:508283-509041:+ | gene-YLR186W_CENPK1137D | rna-NM_001182073.1_CENPK1137D | cds-NP_013287.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005482.1:477278-478036:+ | gene-YLR186W_EthanolRed | rna-NM_001182073.1_EthanolRed | cds-NP_013287.1_EthanolRed | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005546.1:506205-506963:+ | gene-YLR186W_FaliES1 | rna-NM_001182073.1_FaliES1 | cds-NP_013287.1_FaliES1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000004.1:33104-33862:+ | gene-YLR186W_JAY291 | rna-NM_001182073.1_JAY291 | cds-NP_013287.1_JAY291 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005418.1:518022-518780:+ | gene-YLR186W_MUCL30387 | rna-NM_001182073.1_MUCL30387 | cds-NP_013287.1_MUCL30387 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005450.1:522954-523712:+ | gene-YLR186W_MUCL30388 | rna-NM_001182073.1_MUCL30388 | cds-NP_013287.1_MUCL30388 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005290.1:514230-514988:+ | gene-YLR186W_MUCL39482 | rna-NM_001182073.1_MUCL39482 | cds-NP_013287.1_MUCL39482 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005434.1:514726-515484:+ | gene-YLR186W_MUCL42920 | rna-NM_001182073.1_MUCL42920 | cds-NP_013287.1_MUCL42920 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011821.1:523606-524364:+ | gene-YLR186W_NCIM3186 | rna-NM_001182073.1_NCIM3186 | cds-NP_013287.1_NCIM3186 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005274.1:506657-507415:+ | gene-YLR186W_NCYC1407 | rna-NM_001182073.1_NCYC1407 | cds-NP_013287.1_NCYC1407 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994151.1:510893-511651:+ | gene-YLR186W_PE2H3 | rna-NM_001182073.1_PE2H3 | cds-NP_013287.1_PE2H3 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999883.1:510637-511395:+ | gene-YLR186W_PE2H4 | rna-NM_001182073.1_PE2H4 | cds-NP_013287.1_PE2H4 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001144.5:523632-524390:+ | gene-YLR186W_S288C | rna-NM_001182073.1_S288C | cds-NP_013287.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000042.1:33162-33920:+ | gene-YLR186W_SA1 | rna-NM_001182073.1_SA1 | cds-NP_013287.1_SA1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005498.1:508708-509466:+ | gene-YLR186W_ThermosaccDry | rna-NM_001182073.1_ThermosaccDry | cds-NP_013287.1_ThermosaccDry | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005466.1:520006-520764:+ | gene-YLR186W_VR1 | rna-NM_001182073.1_VR1 | cds-NP_013287.1_VR1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000024.1:32998-33756:+ | gene-YLR186W_ZTW1 | rna-NM_001182073.1_ZTW1 | cds-NP_013287.1_ZTW1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047498.1:494844-495602:+ | gene-YLR186W_Sparadoxus | rna-NM_001182073.1_Sparadoxus | cds-NP_013287.1_Sparadoxus | 94.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |