EMC5 (YIL027C)


Gene profile

Gene name: EMC5
Reference locus (S288C): YIL027C
Gene biotype: protein_coding

Description: Member of conserved ER transmembrane complex; required for efficient folding of proteins in the ER; null mutant displays induction of the unfolded protein response, and also shows K1 killer toxin resistance; homologous to worm B0334.15/EMC-5, fly CG15168, human MMGT

Top 10 interactors (score): EMC3 (0.998); EMC1 (0.998); EMC2 (0.998); EMC6 (0.998); EMC4 (0.998); EMC10 (0.982); SOP4 (0.965); TOM5 (0.689); ILM1 (0.674); ICE2 (0.63); EMP65 (0.575); YOR1 (0.493); RPL15A (0.487); GPI18 (0.446); HRD3 (0.442); SPF1 (0.405); GET1 (0.403); PHO88 (0.402)

Homologues (species, bitscore): Unknown

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005303.1:302134-302559:- gene-YIL027C_AKU4011 rna-NM_001179377.1_AKU4011 cds-NP_012237.1_AKU4011 100.0 100.0 Verified 1 1 1 True True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000164.1:161959-162384:- gene-YIL027C_BG1 rna-NM_001179377.1_BG1 cds-NP_012237.1_BG1 99.7 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005511.1:307276-307701:- gene-YIL027C_Bruggeman rna-NM_001179377.1_Bruggeman cds-NP_012237.1_Bruggeman 99.7 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005527.1:294693-295118:- gene-YIL027C_CAT1 rna-NM_001179377.1_CAT1 cds-NP_012237.1_CAT1 100.0 100.0 Verified 1 1 1 True True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005367.1:302223-302648:- gene-YIL027C_CBS1585 rna-NM_001179377.1_CBS1585 cds-NP_012237.1_CBS1585 99.7 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005351.1:295657-296082:- gene-YIL027C_CBS436 rna-NM_001179377.1_CBS436 cds-NP_012237.1_CBS436 100.0 100.0 Mismatch 1 1 1 True True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005335.1:297755-298180:- gene-YIL027C_CBS6412 rna-NM_001179377.1_CBS6412 cds-NP_012237.1_CBS6412 100.0 100.0 Mismatch 1 1 1 True True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005319.1:294139-294564:- gene-YIL027C_CBS6413 rna-NM_001179377.1_CBS6413 cds-NP_012237.1_CBS6413 100.0 100.0 Verified 1 1 1 True True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001530.1:295588-296013:- gene-YIL027C_CENPK1137D rna-NM_001179377.1_CENPK1137D cds-NP_012237.1_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005479.1:285101-285526:- gene-YIL027C_EthanolRed rna-NM_001179377.1_EthanolRed cds-NP_012237.1_EthanolRed 100.0 100.0 Verified 1 1 1 True True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005543.1:303012-303437:- gene-YIL027C_FaliES1 rna-NM_001179377.1_FaliES1 cds-NP_012237.1_FaliES1 100.0 100.0 Verified 1 1 1 True True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000098.1:13551-13976:+ gene-YIL027C_JAY291 rna-NM_001179377.1_JAY291 cds-NP_012237.1_JAY291 99.7 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005415.1:304126-304551:- gene-YIL027C_MUCL30387 rna-NM_001179377.1_MUCL30387 cds-NP_012237.1_MUCL30387 99.7 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005447.1:300231-300656:- gene-YIL027C_MUCL30388 rna-NM_001179377.1_MUCL30388 cds-NP_012237.1_MUCL30388 99.7 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005287.1:302814-303239:- gene-YIL027C_MUCL39482 rna-NM_001179377.1_MUCL39482 cds-NP_012237.1_MUCL39482 100.0 100.0 Verified 1 1 1 True True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005431.1:305942-306367:- gene-YIL027C_MUCL42920 rna-NM_001179377.1_MUCL42920 cds-NP_012237.1_MUCL42920 100.0 100.0 Verified 1 1 1 True True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011818.1:303679-304104:- gene-YIL027C_NCIM3186 rna-NM_001179377.1_NCIM3186 cds-NP_012237.1_NCIM3186 100.0 100.0 Verified 1 1 1 True True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005271.1:307087-307512:- gene-YIL027C_NCYC1407 rna-NM_001179377.1_NCYC1407 cds-NP_012237.1_NCYC1407 100.0 100.0 Verified 1 1 1 True True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994148.1:298728-299153:- gene-YIL027C_PE2H3 rna-NM_001179377.1_PE2H3 cds-NP_012237.1_PE2H3 100.0 100.0 Verified 1 1 1 True True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999880.1:293434-293859:- gene-YIL027C_PE2H4 rna-NM_001179377.1_PE2H4 cds-NP_012237.1_PE2H4 100.0 100.0 Verified 1 1 1 True True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001141.2:303679-304104:- gene-YIL027C_S288C rna-NM_001179377.1_S288C cds-NP_012237.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000031.1:20430-20855:+ gene-YIL027C_SA1 rna-NM_001179377.1_SA1 cds-NP_012237.1_SA1 100.0 100.0 Verified 1 1 1 True True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005495.1:301681-302106:- gene-YIL027C_ThermosaccDry rna-NM_001179377.1_ThermosaccDry cds-NP_012237.1_ThermosaccDry 100.0 100.0 Verified 1 1 1 True True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005463.1:298316-298741:- gene-YIL027C_VR1 rna-NM_001179377.1_VR1 cds-NP_012237.1_VR1 100.0 100.0 Verified 1 1 1 True True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000019.1:276101-276526:- gene-YIL027C_ZTW1 rna-NM_001179377.1_ZTW1 cds-NP_012237.1_ZTW1 99.7 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047495.1:296832-297257:- gene-YIL027C_Sparadoxus rna-NM_001179377.1_Sparadoxus cds-NP_012237.1_Sparadoxus 90.6 100.0 Verified 1 1 1 False True False False False

Additional files