Gene name: EMC3
Reference locus (S288C): YKL207W
Gene biotype: protein_coding
Description: Member of conserved ER transmembrane complex; required for efficient folding of proteins in the ER; required for respiratory growth; null mutant displays induction of the unfolded protein response; homologous to worm Y62E10A.10/EMC-3, fly CG6750, human TMEM111
Top 10 interactors (score): EMC1 (0.999); EMC4 (0.999); EMC6 (0.999); EMC2 (0.999); EMC5 (0.998); EMC10 (0.996); SOP4 (0.983); OXA1 (0.946); GET1 (0.93); DDI1 (0.856); TOP1 (0.789); CBC2 (0.764); OPI3 (0.723); YKL033W-A (0.712); SKG1 (0.712); PTK1 (0.701); ECM9 (0.696); COX18 (0.662); RRT8 (0.659); BCH1 (0.619)
Homologues (species, bitscore): EMC3 (Homo sapiens, 130.2); Emc3 (Mus musculus, 130.6); zgc:86609 (Danio rerio, 142.9); emc3 (Xenopus tropicalis, 129.4); CG6750 (Drosophila melanogaster, 127.5); Y62E10A.10 (Caenorhabditis elegans, 142.5); AT4G12590 (Arabidopsis thaliana, 141.0)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005305.1:34508-35269:+ | gene-YKL207W_AKU4011 | rna-NM_001179772.1_AKU4011 | cds-NP_012715.3_AKU4011 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000030.1:11592-12353:+ | gene-YKL207W_BG1 | rna-NM_001179772.1_BG1 | cds-NP_012715.3_BG1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005513.1:52180-52941:+ | gene-YKL207W_Bruggeman | rna-NM_001179772.1_Bruggeman | cds-NP_012715.3_Bruggeman | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005529.1:47371-48132:+ | gene-YKL207W_CAT1 | rna-NM_001179772.1_CAT1 | cds-NP_012715.3_CAT1 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005369.1:46520-47281:+ | gene-YKL207W_CBS1585 | rna-NM_001179772.1_CBS1585 | cds-NP_012715.3_CBS1585 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005353.1:45721-46482:+ | gene-YKL207W_CBS436 | rna-NM_001179772.1_CBS436 | cds-NP_012715.3_CBS436 | 99.2 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005337.1:31777-32538:+ | gene-YKL207W_CBS6412 | rna-NM_001179772.1_CBS6412 | cds-NP_012715.3_CBS6412 | 99.6 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005321.1:47157-47918:+ | gene-YKL207W_CBS6413 | rna-NM_001179772.1_CBS6413 | cds-NP_012715.3_CBS6413 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001532.1:47972-48737:+ | gene-YKL207W_CENPK1137D | rna-NM_001179772.1_CENPK1137D | cds-NP_012715.3_CENPK1137D | 99.4 | 100.0 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005481.1:45991-46752:+ | gene-YKL207W_EthanolRed | rna-NM_001179772.1_EthanolRed | cds-NP_012715.3_EthanolRed | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005545.1:46050-46811:+ | gene-YKL207W_FaliES1 | rna-NM_001179772.1_FaliES1 | cds-NP_012715.3_FaliES1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000006.2:45664-46425:+ | gene-YKL207W_JAY291 | rna-NM_001179772.1_JAY291 | cds-NP_012715.3_JAY291 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005417.1:54715-55476:+ | gene-YKL207W_MUCL30387 | rna-NM_001179772.1_MUCL30387 | cds-NP_012715.3_MUCL30387 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005449.1:48803-49564:+ | gene-YKL207W_MUCL30388 | rna-NM_001179772.1_MUCL30388 | cds-NP_012715.3_MUCL30388 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005289.1:46577-47338:+ | gene-YKL207W_MUCL39482 | rna-NM_001179772.1_MUCL39482 | cds-NP_012715.3_MUCL39482 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005433.1:49871-50632:+ | gene-YKL207W_MUCL42920 | rna-NM_001179772.1_MUCL42920 | cds-NP_012715.3_MUCL42920 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011820.1:48183-48944:+ | gene-YKL207W_NCIM3186 | rna-NM_001179772.1_NCIM3186 | cds-NP_012715.3_NCIM3186 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005273.1:46601-47362:+ | gene-YKL207W_NCYC1407 | rna-NM_001179772.1_NCYC1407 | cds-NP_012715.3_NCYC1407 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994150.1:54299-55060:+ | gene-YKL207W_PE2H3 | rna-NM_001179772.1_PE2H3 | cds-NP_012715.3_PE2H3 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999882.1:50497-51258:+ | gene-YKL207W_PE2H4 | rna-NM_001179772.1_PE2H4 | cds-NP_012715.3_PE2H4 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001143.9:48194-48955:+ | gene-YKL207W_S288C | rna-NM_001179772.1_S288C | cds-NP_012715.3_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000092.1:18918-19679:- | gene-YKL207W_SA1 | rna-NM_001179772.1_SA1 | cds-NP_012715.3_SA1 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005497.1:46798-47559:+ | gene-YKL207W_ThermosaccDry | rna-NM_001179772.1_ThermosaccDry | cds-NP_012715.3_ThermosaccDry | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005465.1:45903-46664:+ | gene-YKL207W_VR1 | rna-NM_001179772.1_VR1 | cds-NP_012715.3_VR1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000022.1:45712-46473:+ | gene-YKL207W_ZTW1 | rna-NM_001179772.1_ZTW1 | cds-NP_012715.3_ZTW1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047497.1:54459-55220:+ | gene-YKL207W_Sparadoxus | rna-NM_001179772.1_Sparadoxus | cds-NP_012715.3_Sparadoxus | 90.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |