EMC2 (YJR088C)


Gene profile

Gene name: EMC2
Reference locus (S288C): YJR088C
Gene biotype: protein_coding

Description: Member of conserved ER transmembrane complex; required for efficient folding of proteins in the ER; null mutant displays induction of the unfolded protein response; homologous to worm Y57G7A.10/EMC-2, fly CG17556, human TTC35

Top 10 interactors (score): EMC6 (0.999); EMC3 (0.999); EMC1 (0.999); EMC4 (0.999); EMC5 (0.998); EMC10 (0.992); SOP4 (0.968); YOR289W (0.962); CHO2 (0.767); ERG9 (0.719); ALG3 (0.701); PBR1 (0.7); DPM1 (0.653); YET1 (0.633); YET3 (0.631); TMA46 (0.626); PSD1 (0.602); OPI3 (0.598); NVJ2 (0.59); ALG12 (0.575)

Homologues (species, bitscore): Unknown

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005304.1:558024-558902:- gene-YJR088C_AKU4011 rna-NM_001181745.1_AKU4011 cds-NP_012621.1_AKU4011 99.5 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000190.1:48670-49548:+ gene-YJR088C_BG1 rna-NM_001181745.1_BG1 cds-NP_012621.1_BG1 99.5 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005512.1:571538-572416:- gene-YJR088C_Bruggeman rna-NM_001181745.1_Bruggeman cds-NP_012621.1_Bruggeman 99.5 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005528.1:575937-576815:- gene-YJR088C_CAT1 rna-NM_001181745.1_CAT1 cds-NP_012621.1_CAT1 98.9 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005368.1:570088-570966:- gene-YJR088C_CBS1585 rna-NM_001181745.1_CBS1585 cds-NP_012621.1_CBS1585 99.5 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005352.1:588163-589041:- gene-YJR088C_CBS436 rna-NM_001181745.1_CBS436 cds-NP_012621.1_CBS436 99.0 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005336.1:557236-558114:- gene-YJR088C_CBS6412 rna-NM_001181745.1_CBS6412 cds-NP_012621.1_CBS6412 99.6 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005320.1:559530-560408:- gene-YJR088C_CBS6413 rna-NM_001181745.1_CBS6413 cds-NP_012621.1_CBS6413 99.6 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001531.1:568851-569729:- gene-YJR088C_CENPK1137D rna-NM_001181745.1_CENPK1137D cds-NP_012621.1_CENPK1137D 99.0 100.0 Verified 1 1 1 False True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005480.1:562414-563292:- gene-YJR088C_EthanolRed rna-NM_001181745.1_EthanolRed cds-NP_012621.1_EthanolRed 99.8 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005544.1:573880-574758:- gene-YJR088C_FaliES1 rna-NM_001181745.1_FaliES1 cds-NP_012621.1_FaliES1 99.7 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000054.1:114627-115505:+ gene-YJR088C_JAY291 rna-NM_001181745.1_JAY291 cds-NP_012621.1_JAY291 99.5 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005416.1:572067-572945:- gene-YJR088C_MUCL30387 rna-NM_001181745.1_MUCL30387 cds-NP_012621.1_MUCL30387 99.5 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005448.1:569363-570241:- gene-YJR088C_MUCL30388 rna-NM_001181745.1_MUCL30388 cds-NP_012621.1_MUCL30388 99.5 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005288.1:563548-564426:- gene-YJR088C_MUCL39482 rna-NM_001181745.1_MUCL39482 cds-NP_012621.1_MUCL39482 99.5 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005432.1:567794-568672:- gene-YJR088C_MUCL42920 rna-NM_001181745.1_MUCL42920 cds-NP_012621.1_MUCL42920 99.5 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011819.1:586474-587352:- gene-YJR088C_NCIM3186 rna-NM_001181745.1_NCIM3186 cds-NP_012621.1_NCIM3186 99.4 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005272.1:561114-561992:- gene-YJR088C_NCYC1407 rna-NM_001181745.1_NCYC1407 cds-NP_012621.1_NCYC1407 99.6 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994149.1:579011-579889:- gene-YJR088C_PE2H3 rna-NM_001181745.1_PE2H3 cds-NP_012621.1_PE2H3 99.0 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999881.1:572700-573578:- gene-YJR088C_PE2H4 rna-NM_001181745.1_PE2H4 cds-NP_012621.1_PE2H4 99.5 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001142.9:586495-587373:- gene-YJR088C_S288C rna-NM_001181745.1_S288C cds-NP_012621.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000038.1:45076-45954:- gene-YJR088C_SA1 rna-NM_001181745.1_SA1 cds-NP_012621.1_SA1 99.5 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005496.1:567814-568692:- gene-YJR088C_ThermosaccDry rna-NM_001181745.1_ThermosaccDry cds-NP_012621.1_ThermosaccDry 99.7 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005464.1:569969-570847:- gene-YJR088C_VR1 rna-NM_001181745.1_VR1 cds-NP_012621.1_VR1 98.7 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000021.1:547209-548087:- gene-YJR088C_ZTW1 rna-NM_001181745.1_ZTW1 cds-NP_012621.1_ZTW1 99.5 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047496.1:580574-581452:- gene-YJR088C_Sparadoxus rna-NM_001181745.1_Sparadoxus cds-NP_012621.1_Sparadoxus 90.6 100.0 Verified 1 1 1 False True False False False

Additional files