Gene name: EMC10
Reference locus (S288C): YDR056C
Gene biotype: protein_coding
Description: Uncharacterized protein YDR056C; Putative protein of unknown function; subunit of evolutionarily conserved EMC (Endoplasmic Reticulum Membrane Complex) implicated in ERAD (ER-associated degradation) and proper assembly of multi-pass transmembrane (TM) proteins; EMC acts in yeast as an ER-mitochondria tether that interacts with outer membrane protein Tom5p of TOM (Translocase of the Mitochondrial Outer Membrane) complex; YDR056C is not an essential protein
Top 10 interactors (score): EMC3 (0.996); SOP4 (0.994); EMC6 (0.993); EMC4 (0.992); EMC2 (0.992); EMC1 (0.991); EMC5 (0.982); DET1 (0.872); AIM7 (0.872); TVP23 (0.872); HEM12 (0.872); YOS9 (0.858); VMS1 (0.857); RPC11 (0.856); UBC13 (0.846); RTR2 (0.809); OCA6 (0.808); CDC34 (0.807); YDR061W (0.802); TGL2 (0.766)
Homologues (species, bitscore): Unknown
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005298.1:542566-543183:- | gene-YDR056C_AKU4011 | rna-NM_001180364.3_AKU4011 | cds-NP_010341.3_AKU4011 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000102.1:12032-12649:+ | gene-YDR056C_BG1 | rna-NM_001180364.3_BG1 | cds-NP_010341.3_BG1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005506.1:574904-575521:- | gene-YDR056C_Bruggeman | rna-NM_001180364.3_Bruggeman | cds-NP_010341.3_Bruggeman | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005522.1:557904-558521:- | gene-YDR056C_CAT1 | rna-NM_001180364.3_CAT1 | cds-NP_010341.3_CAT1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005362.1:533520-534137:- | gene-YDR056C_CBS1585 | rna-NM_001180364.3_CBS1585 | cds-NP_010341.3_CBS1585 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005346.1:558686-559303:- | gene-YDR056C_CBS436 | rna-NM_001180364.3_CBS436 | cds-NP_010341.3_CBS436 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005330.1:529932-530549:- | gene-YDR056C_CBS6412 | rna-NM_001180364.3_CBS6412 | cds-NP_010341.3_CBS6412 | 99.0 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005314.1:558601-559218:- | gene-YDR056C_CBS6413 | rna-NM_001180364.3_CBS6413 | cds-NP_010341.3_CBS6413 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001525.1:563990-564607:- | gene-YDR056C_CENPK1137D | rna-NM_001180364.3_CENPK1137D | cds-NP_010341.3_CENPK1137D | 98.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005474.1:544390-545007:- | gene-YDR056C_EthanolRed | rna-NM_001180364.3_EthanolRed | cds-NP_010341.3_EthanolRed | 98.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005538.1:550830-551447:- | gene-YDR056C_FaliES1 | rna-NM_001180364.3_FaliES1 | cds-NP_010341.3_FaliES1 | 98.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000246.1:3267-3884:+ | gene-YDR056C_JAY291 | rna-NM_001180364.3_JAY291 | cds-NP_010341.3_JAY291 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005410.1:559566-560183:- | gene-YDR056C_MUCL30387 | rna-NM_001180364.3_MUCL30387 | cds-NP_010341.3_MUCL30387 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005442.1:549987-550604:- | gene-YDR056C_MUCL30388 | rna-NM_001180364.3_MUCL30388 | cds-NP_010341.3_MUCL30388 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005282.1:534891-535508:- | gene-YDR056C_MUCL39482 | rna-NM_001180364.3_MUCL39482 | cds-NP_010341.3_MUCL39482 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005426.1:465366-465983:- | gene-YDR056C_MUCL42920 | rna-NM_001180364.3_MUCL42920 | cds-NP_010341.3_MUCL42920 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011813.1:564946-565563:- | gene-YDR056C_NCIM3186 | rna-NM_001180364.3_NCIM3186 | cds-NP_010341.3_NCIM3186 | 98.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005266.1:533825-534442:- | gene-YDR056C_NCYC1407 | rna-NM_001180364.3_NCYC1407 | cds-NP_010341.3_NCYC1407 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994143.1:553462-554079:- | gene-YDR056C_PE2H3 | rna-NM_001180364.3_PE2H3 | cds-NP_010341.3_PE2H3 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999875.1:552767-553384:- | gene-YDR056C_PE2H4 | rna-NM_001180364.3_PE2H4 | cds-NP_010341.3_PE2H4 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001136.10:565023-565640:- | gene-YDR056C_S288C | rna-NM_001180364.3_S288C | cds-NP_010341.3_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000011.1:79851-80468:+ | gene-YDR056C_SA1 | rna-NM_001180364.3_SA1 | cds-NP_010341.3_SA1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005490.1:550570-551187:- | gene-YDR056C_ThermosaccDry | rna-NM_001180364.3_ThermosaccDry | cds-NP_010341.3_ThermosaccDry | 98.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005458.1:563276-563893:- | gene-YDR056C_VR1 | rna-NM_001180364.3_VR1 | cds-NP_010341.3_VR1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000006.1:548175-548792:- | gene-YDR056C_ZTW1 | rna-NM_001180364.3_ZTW1 | cds-NP_010341.3_ZTW1 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047490.1:552596-553213:- | gene-YDR056C_Sparadoxus | rna-NM_001180364.3_Sparadoxus | cds-NP_010341.3_Sparadoxus | 89.0 | 99.8 | Verified | 1 | 1 | 1 | False | True | False | False | False |