Gene name: EMC1
Reference locus (S288C): YCL045C
Gene biotype: protein_coding
Description: Member of conserved endoplasmic reticulum membrane complex; involved in efficient folding of proteins in the ER; null mutant displays induction of the unfolded protein response; interacts with Gal80p; homologous to worm H17B01.4/EMC-1, fly CG2943, and human KIAA0090; Belongs to the EMC1 family
Top 10 interactors (score): EMC6 (0.999); EMC3 (0.999); EMC2 (0.999); EMC4 (0.999); EMC5 (0.998); EMC10 (0.991); SOP4 (0.961); OXA1 (0.766); TOM5 (0.765); UTP25 (0.759); RTT103 (0.688); YOR1 (0.663); YGR127W (0.656); PBR1 (0.655); ALE1 (0.653); YMR310C (0.64); YGR283C (0.64); YET1 (0.608); YET3 (0.604); KGD1 (0.604)
Homologues (species, bitscore): EMC1 (Homo sapiens, 128.6); Emc1 (Mus musculus, 129.0); emc1 (Danio rerio, 137.1); emc1 (Xenopus tropicalis, 135.6); CG2943 (Drosophila melanogaster, 150.2); H17B01.4 (Caenorhabditis elegans, 117.5); AT5G11560 (Arabidopsis thaliana, 102.4)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005297.1:45903-48185:- | gene-YCL045C_AKU4011 | rna-NM_001178690.1_AKU4011 | cds-NP_009884.1_AKU4011 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000198.1:54-2336:- | gene-YCL045C_BG1 | rna-NM_001178690.1_BG1 | cds-NP_009884.1_BG1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005505.1:33767-36049:- | gene-YCL045C_Bruggeman | rna-NM_001178690.1_Bruggeman | cds-NP_009884.1_Bruggeman | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005521.1:45788-48070:- | gene-YCL045C_CAT1 | rna-NM_001178690.1_CAT1 | cds-NP_009884.1_CAT1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005361.1:46600-48882:- | gene-YCL045C_CBS1585 | rna-NM_001178690.1_CBS1585 | cds-NP_009884.1_CBS1585 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005345.1:45133-47415:- | gene-YCL045C_CBS436 | rna-NM_001178690.1_CBS436 | cds-NP_009884.1_CBS436 | 99.9 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005329.1:34398-36680:- | gene-YCL045C_CBS6412 | rna-NM_001178690.1_CBS6412 | cds-NP_009884.1_CBS6412 | 99.5 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005313.1:45426-47708:- | gene-YCL045C_CBS6413 | rna-NM_001178690.1_CBS6413 | cds-NP_009884.1_CBS6413 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001524.1:44188-46470:- | gene-YCL045C_CENPK1137D | rna-NM_001178690.1_CENPK1137D | cds-NP_009884.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005473.1:44161-46443:- | gene-YCL045C_EthanolRed | rna-NM_001178690.1_EthanolRed | cds-NP_009884.1_EthanolRed | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005537.1:44926-47208:- | gene-YCL045C_FaliES1 | rna-NM_001178690.1_FaliES1 | cds-NP_009884.1_FaliES1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000225.1:37137-39419:+ | gene-YCL045C_JAY291 | rna-NM_001178690.1_JAY291 | cds-NP_009884.1_JAY291 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005409.1:32370-34652:- | gene-YCL045C_MUCL30387 | rna-NM_001178690.1_MUCL30387 | cds-NP_009884.1_MUCL30387 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005441.1:32645-34927:- | gene-YCL045C_MUCL30388 | rna-NM_001178690.1_MUCL30388 | cds-NP_009884.1_MUCL30388 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005281.1:46993-49275:- | gene-YCL045C_MUCL39482 | rna-NM_001178690.1_MUCL39482 | cds-NP_009884.1_MUCL39482 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005425.1:33161-35443:- | gene-YCL045C_MUCL42920 | rna-NM_001178690.1_MUCL42920 | cds-NP_009884.1_MUCL42920 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011812.1:44255-46537:- | gene-YCL045C_NCIM3186 | rna-NM_001178690.1_NCIM3186 | cds-NP_009884.1_NCIM3186 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005265.1:47323-49605:- | gene-YCL045C_NCYC1407 | rna-NM_001178690.1_NCYC1407 | cds-NP_009884.1_NCYC1407 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994142.1:45090-47372:- | gene-YCL045C_PE2H3 | rna-NM_001178690.1_PE2H3 | cds-NP_009884.1_PE2H3 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999874.1:45047-47329:- | gene-YCL045C_PE2H4 | rna-NM_001178690.1_PE2H4 | cds-NP_009884.1_PE2H4 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001135.5:44623-46905:- | gene-YCL045C_S288C | rna-NM_001178690.1_S288C | cds-NP_009884.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000061.1:31769-34051:- | gene-YCL045C_SA1 | rna-NM_001178690.1_SA1 | cds-NP_009884.1_SA1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005489.1:45243-47525:- | gene-YCL045C_ThermosaccDry | rna-NM_001178690.1_ThermosaccDry | cds-NP_009884.1_ThermosaccDry | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005457.1:51561-53843:- | gene-YCL045C_VR1 | rna-NM_001178690.1_VR1 | cds-NP_009884.1_VR1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000004.1:45452-47734:- | gene-YCL045C_ZTW1 | rna-NM_001178690.1_ZTW1 | cds-NP_009884.1_ZTW1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047489.1:75084-77423:- | gene-YCL045C_Sparadoxus | rna-NM_001178690.1_Sparadoxus | cds-NP_009884.1_Sparadoxus | 86.2 | 99.8 | Verified | 1 | 1 | 1 | False | True | False | False | False |