ELP4 (YPL101W)


Gene profile

Gene name: ELP4
Reference locus (S288C): YPL101W
Gene biotype: protein_coding

Description: Subunit of hexameric RecA-like ATPase Elp456 Elongator subcomplex; which is required for modification of wobble nucleosides in tRNA; required for Elongator structural integrity; null mutation is functionally complemented by human ELP4

Top 10 interactors (score): IKI1 (0.999); IKI3 (0.999); ELP2 (0.999); ELP6 (0.999); ELP3 (0.999); KTI12 (0.976); FOX2 (0.96); KTI11 (0.95); URM1 (0.933); UBA4 (0.931); NCS6 (0.928); TRM9 (0.885); HHT1 (0.879); HHT2 (0.874); HHF1 (0.851); NCS2 (0.851); HHF2 (0.851); TRM112 (0.775); TAF9 (0.736); BIM1 (0.712)

Homologues (species, bitscore): ELP4 (Homo sapiens, 64.7); Elp4 (Mus musculus, 69.7); elp4 (Danio rerio, 57.8); elp4 (Xenopus tropicalis, 50.4)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005310.1:337849-339219:+ gene-YPL101W_AKU4011 rna-NM_001183915.1_AKU4011 cds-NP_015224.1_AKU4011 99.2 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000069.1:543604-544974:+ gene-YPL101W_BG1 rna-NM_001183915.1_BG1 cds-NP_015224.1_BG1 99.7 100.0 Verified 1 1 1 True True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005518.1:363857-365227:+ gene-YPL101W_Bruggeman rna-NM_001183915.1_Bruggeman cds-NP_015224.1_Bruggeman 99.4 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005534.1:361347-362691:+ gene-YPL101W_CAT1 rna-NM_001183915.1_CAT1 cds-NP_015224.1_CAT1 94.4 97.3 Unannotated 1 1 0 False False True False False
CBS1585 GCA_001738375.1 Sake Asia CM005374.1:341922-343292:+ gene-YPL101W_CBS1585 rna-NM_001183915.1_CBS1585 cds-NP_015224.1_CBS1585 99.2 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005358.1:356596-357966:+ gene-YPL101W_CBS436 rna-NM_001183915.1_CBS436 cds-NP_015224.1_CBS436 99.9 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005342.1:346591-347961:+ gene-YPL101W_CBS6412 rna-NM_001183915.1_CBS6412 cds-NP_015224.1_CBS6412 99.2 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005326.1:338558-339928:+ gene-YPL101W_CBS6413 rna-NM_001183915.1_CBS6413 cds-NP_015224.1_CBS6413 99.2 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001537.1:360157-361527:+ gene-YPL101W_CENPK1137D rna-NM_001183915.1_CENPK1137D cds-NP_015224.1_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005486.1:336541-337911:+ gene-YPL101W_EthanolRed rna-NM_001183915.1_EthanolRed cds-NP_015224.1_EthanolRed 99.1 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005550.1:344133-345503:+ gene-YPL101W_FaliES1 rna-NM_001183915.1_FaliES1 cds-NP_015224.1_FaliES1 99.1 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000007.1:20313-21683:- gene-YPL101W_JAY291 rna-NM_001183915.1_JAY291 cds-NP_015224.1_JAY291 99.2 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005422.1:355095-356465:+ gene-YPL101W_MUCL30387 rna-NM_001183915.1_MUCL30387 cds-NP_015224.1_MUCL30387 100.0 100.0 Verified 1 1 1 True True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005440.1:579613-580983:+ gene-YPL101W_MUCL30388 rna-NM_001183915.1_MUCL30388 cds-NP_015224.1_MUCL30388 99.6 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005294.1:335251-336621:+ gene-YPL101W_MUCL39482 rna-NM_001183915.1_MUCL39482 cds-NP_015224.1_MUCL39482 99.2 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005438.1:392939-394309:+ gene-YPL101W_MUCL42920 rna-NM_001183915.1_MUCL42920 cds-NP_015224.1_MUCL42920 99.4 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011825.1:360192-361562:+ gene-YPL101W_NCIM3186 rna-NM_001183915.1_NCIM3186 cds-NP_015224.1_NCIM3186 98.7 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005278.1:341704-343074:+ gene-YPL101W_NCYC1407 rna-NM_001183915.1_NCYC1407 cds-NP_015224.1_NCYC1407 99.1 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994155.1:349196-350566:+ gene-YPL101W_PE2H3 rna-NM_001183915.1_PE2H3 cds-NP_015224.1_PE2H3 99.7 100.0 Verified 1 1 1 True True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999887.1:348819-350189:+ gene-YPL101W_PE2H4 rna-NM_001183915.1_PE2H4 cds-NP_015224.1_PE2H4 99.7 100.0 Verified 1 1 1 True True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001148.4:360209-361579:+ gene-YPL101W_S288C rna-NM_001183915.1_S288C cds-NP_015224.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000012.1:12100-13470:- gene-YPL101W_SA1 rna-NM_001183915.1_SA1 cds-NP_015224.1_SA1 100.0 100.0 Verified 1 1 1 True True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005502.1:343931-345301:+ gene-YPL101W_ThermosaccDry rna-NM_001183915.1_ThermosaccDry cds-NP_015224.1_ThermosaccDry 99.1 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005470.1:358907-360277:+ gene-YPL101W_VR1 rna-NM_001183915.1_VR1 cds-NP_015224.1_VR1 99.7 100.0 Verified 1 1 1 True True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000033.1:343252-344622:+ gene-YPL101W_ZTW1 rna-NM_001183915.1_ZTW1 cds-NP_015224.1_ZTW1 99.1 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047502.1:344921-346300:+ gene-YPL101W_Sparadoxus rna-NM_001183915.1_Sparadoxus cds-NP_015224.1_Sparadoxus 87.1 100.0 Verified 1 1 1 False True False False False

Additional files