Gene name: ELP3
Reference locus (S288C): YPL086C
Gene biotype: protein_coding
Description: Subunit of Elongator complex; Elongator is required for modification of wobble nucleosides in tRNA; exhibits histone acetyltransferase activity that is directed to histones H3 and H4; disruption confers resistance to K. lactis zymotoxin; human homolog ELP3 can partially complement yeast elp3 null mutant
Top 10 interactors (score): IKI1 (0.999); ELP2 (0.999); ELP4 (0.999); IKI3 (0.999); ELP6 (0.999); KTI12 (0.998); KTI11 (0.992); NCS6 (0.989); GCN5 (0.986); NMD3 (0.983); NOC2 (0.981); MCM5 (0.976); URM1 (0.975); TRM9 (0.963); ERB1 (0.962); UBA4 (0.958); NCS2 (0.953); TRM1 (0.93); SAS3 (0.929); NOC4 (0.929)
Homologues (species, bitscore): ELP3 (Homo sapiens, 855.5); Elp3 (Mus musculus, 847.0); elp3 (Danio rerio, 865.1); elp3 (Xenopus tropicalis, 823.2); Elp3 (Drosophila melanogaster, 846.3); elpc-3 (Caenorhabditis elegans, 813.1); ELO3 (Arabidopsis thaliana, 796.2)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005310.1:362517-364190:- | gene-YPL086C_AKU4011 | rna-NM_001183900.1_AKU4011 | cds-NP_015239.1_AKU4011 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000069.1:568197-569870:- | gene-YPL086C_BG1 | rna-NM_001183900.1_BG1 | cds-NP_015239.1_BG1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005518.1:438840-440513:- | gene-YPL086C_Bruggeman | rna-NM_001183900.1_Bruggeman | cds-NP_015239.1_Bruggeman | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005534.1:479179-480852:- | gene-YPL086C_CAT1 | rna-NM_001183900.1_CAT1 | cds-NP_015239.1_CAT1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005374.1:366584-368257:- | gene-YPL086C_CBS1585 | rna-NM_001183900.1_CBS1585 | cds-NP_015239.1_CBS1585 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005358.1:381133-382806:- | gene-YPL086C_CBS436 | rna-NM_001183900.1_CBS436 | cds-NP_015239.1_CBS436 | 99.9 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005342.1:370778-372451:- | gene-YPL086C_CBS6412 | rna-NM_001183900.1_CBS6412 | cds-NP_015239.1_CBS6412 | 99.6 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005326.1:363132-364805:- | gene-YPL086C_CBS6413 | rna-NM_001183900.1_CBS6413 | cds-NP_015239.1_CBS6413 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001537.1:384769-386442:- | gene-YPL086C_CENPK1137D | rna-NM_001183900.1_CENPK1137D | cds-NP_015239.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005486.1:360880-362553:- | gene-YPL086C_EthanolRed | rna-NM_001183900.1_EthanolRed | cds-NP_015239.1_EthanolRed | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005550.1:368710-370383:- | gene-YPL086C_FaliES1 | rna-NM_001183900.1_FaliES1 | cds-NP_015239.1_FaliES1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000350.1:20857-22530:+ | gene-YPL086C_JAY291 | rna-NM_001183900.1_JAY291 | cds-NP_015239.1_JAY291 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005422.1:379669-381342:- | gene-YPL086C_MUCL30387 | rna-NM_001183900.1_MUCL30387 | cds-NP_015239.1_MUCL30387 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005454.1:378472-380145:- | gene-YPL086C_MUCL30388 | rna-NM_001183900.1_MUCL30388 | cds-NP_015239.1_MUCL30388 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005294.1:359913-361586:- | gene-YPL086C_MUCL39482 | rna-NM_001183900.1_MUCL39482 | cds-NP_015239.1_MUCL39482 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005438.1:417777-419450:- | gene-YPL086C_MUCL42920 | rna-NM_001183900.1_MUCL42920 | cds-NP_015239.1_MUCL42920 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011825.1:384756-386429:- | gene-YPL086C_NCIM3186 | rna-NM_001183900.1_NCIM3186 | cds-NP_015239.1_NCIM3186 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005278.1:366524-368197:- | gene-YPL086C_NCYC1407 | rna-NM_001183900.1_NCYC1407 | cds-NP_015239.1_NCYC1407 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994155.1:373792-375465:- | gene-YPL086C_PE2H3 | rna-NM_001183900.1_PE2H3 | cds-NP_015239.1_PE2H3 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999887.1:373415-375088:- | gene-YPL086C_PE2H4 | rna-NM_001183900.1_PE2H4 | cds-NP_015239.1_PE2H4 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001148.4:384773-386446:- | gene-YPL086C_S288C | rna-NM_001183900.1_S288C | cds-NP_015239.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000057.1:6889-8562:- | gene-YPL086C_SA1 | rna-NM_001183900.1_SA1 | cds-NP_015239.1_SA1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005502.1:368510-370183:- | gene-YPL086C_ThermosaccDry | rna-NM_001183900.1_ThermosaccDry | cds-NP_015239.1_ThermosaccDry | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005470.1:383501-385174:- | gene-YPL086C_VR1 | rna-NM_001183900.1_VR1 | cds-NP_015239.1_VR1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000033.1:367821-369494:- | gene-YPL086C_ZTW1 | rna-NM_001183900.1_ZTW1 | cds-NP_015239.1_ZTW1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047502.1:369423-371096:- | gene-YPL086C_Sparadoxus | rna-NM_001183900.1_Sparadoxus | cds-NP_015239.1_Sparadoxus | 93.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |