ELO3 (YLR372W)


Gene profile

Gene name: ELO3
Reference locus (S288C): YLR372W
Gene biotype: protein_coding

Description: Elongation of fatty acids protein 3; Elongase; involved in fatty acid and sphingolipid biosynthesis; synthesizes very long chain 20-26-carbon fatty acids from C18-CoA primers; involved in regulation of sphingolipid biosynthesis; lethality of the elo2 elo3 double null mutation is functionally complemented by human ELOVL1 and weakly complemented by human ELOVL3 or ELOV7; Belongs to the ELO family

Top 10 interactors (score): ELO2 (0.995); TSC13 (0.995); IFA38 (0.988); PHS1 (0.972); OLE1 (0.971); RVS161 (0.905); LAC1 (0.874); ERG2 (0.863); SCP1 (0.853); CEM1 (0.828); LCB3 (0.823); ELO1 (0.815); UPC2 (0.811); RVS167 (0.81); VRG4 (0.807); IPT1 (0.793); ERG25 (0.787); LAG1 (0.787); ERG3 (0.764); AUR1 (0.763)

Homologues (species, bitscore): ELOVL2 (Homo sapiens, 76.6); Elovl6 (Mus musculus, 76.3); elovl7a (Danio rerio, 85.1); elovl1 (Xenopus tropicalis, 76.6); Baldspot (Drosophila melanogaster, 84.7); elo-7 (Caenorhabditis elegans, 99.0); AT3G06470 (Arabidopsis thaliana, 87.8)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005306.1:816889-817926:+ gene-YLR372W_AKU4011 rna-NM_001182261.3_AKU4011 cds-NP_013476.3_AKU4011 100.0 100.0 Verified 1 1 1 True True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000048.1:49040-50077:+ gene-YLR372W_BG1 rna-NM_001182261.3_BG1 cds-NP_013476.3_BG1 99.9 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005514.1:855223-856260:+ gene-YLR372W_Bruggeman rna-NM_001182261.3_Bruggeman cds-NP_013476.3_Bruggeman 99.8 100.0 Verified 1 1 1 True True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005530.1:850716-851753:+ gene-YLR372W_CAT1 rna-NM_001182261.3_CAT1 cds-NP_013476.3_CAT1 99.8 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005370.1:851879-852916:+ gene-YLR372W_CBS1585 rna-NM_001182261.3_CBS1585 cds-NP_013476.3_CBS1585 100.0 100.0 Verified 1 1 1 True True False False False
CBS436 GCA_001738355.1 Sake Asia CM005354.1:836121-837158:+ gene-YLR372W_CBS436 rna-NM_001182261.3_CBS436 cds-NP_013476.3_CBS436 99.9 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005338.1:888901-889938:+ gene-YLR372W_CBS6412 rna-NM_001182261.3_CBS6412 cds-NP_013476.3_CBS6412 100.0 100.0 Mismatch 1 1 1 True True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005322.1:852772-853809:+ gene-YLR372W_CBS6413 rna-NM_001182261.3_CBS6413 cds-NP_013476.3_CBS6413 100.0 100.0 Verified 1 1 1 True True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001533.1:852088-853125:+ gene-YLR372W_CENPK1137D rna-NM_001182261.3_CENPK1137D cds-NP_013476.3_CENPK1137D 99.9 100.0 Verified 1 1 1 False True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005482.1:809470-810507:+ gene-YLR372W_EthanolRed rna-NM_001182261.3_EthanolRed cds-NP_013476.3_EthanolRed 100.0 100.0 Verified 1 1 1 True True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005546.1:838275-839312:+ gene-YLR372W_FaliES1 rna-NM_001182261.3_FaliES1 cds-NP_013476.3_FaliES1 100.0 100.0 Verified 1 1 1 True True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000161.1:48859-49896:+ gene-YLR372W_JAY291 rna-NM_001182261.3_JAY291 cds-NP_013476.3_JAY291 99.8 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005418.1:852627-853664:+ gene-YLR372W_MUCL30387 rna-NM_001182261.3_MUCL30387 cds-NP_013476.3_MUCL30387 100.0 100.0 Verified 1 1 1 True True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005450.1:858257-859294:+ gene-YLR372W_MUCL30388 rna-NM_001182261.3_MUCL30388 cds-NP_013476.3_MUCL30388 99.9 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005290.1:853098-854135:+ gene-YLR372W_MUCL39482 rna-NM_001182261.3_MUCL39482 cds-NP_013476.3_MUCL39482 100.0 100.0 Verified 1 1 1 True True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005434.1:848395-849432:+ gene-YLR372W_MUCL42920 rna-NM_001182261.3_MUCL42920 cds-NP_013476.3_MUCL42920 99.8 100.0 Verified 1 1 1 True True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011821.1:867328-868365:+ gene-YLR372W_NCIM3186 rna-NM_001182261.3_NCIM3186 cds-NP_013476.3_NCIM3186 99.8 100.0 Verified 1 1 1 True True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005274.1:862320-863357:+ gene-YLR372W_NCYC1407 rna-NM_001182261.3_NCYC1407 cds-NP_013476.3_NCYC1407 100.0 100.0 Verified 1 1 1 True True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994151.1:849278-850315:+ gene-YLR372W_PE2H3 rna-NM_001182261.3_PE2H3 cds-NP_013476.3_PE2H3 99.8 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999883.1:849022-850059:+ gene-YLR372W_PE2H4 rna-NM_001182261.3_PE2H4 cds-NP_013476.3_PE2H4 99.8 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001144.5:867354-868391:+ gene-YLR372W_S288C rna-NM_001182261.3_S288C cds-NP_013476.3_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000007.1:180301-181338:- gene-YLR372W_SA1 rna-NM_001182261.3_SA1 cds-NP_013476.3_SA1 99.8 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005498.1:841356-842393:+ gene-YLR372W_ThermosaccDry rna-NM_001182261.3_ThermosaccDry cds-NP_013476.3_ThermosaccDry 99.9 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005466.1:854368-855405:+ gene-YLR372W_VR1 rna-NM_001182261.3_VR1 cds-NP_013476.3_VR1 99.8 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000025.1:178542-179579:+ gene-YLR372W_ZTW1 rna-NM_001182261.3_ZTW1 cds-NP_013476.3_ZTW1 99.8 100.0 Verified 1 1 1 True True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047498.1:827243-828280:+ gene-YLR372W_Sparadoxus rna-NM_001182261.3_Sparadoxus cds-NP_013476.3_Sparadoxus 92.8 100.0 Verified 1 1 1 False True False False False

Additional files