Gene name: ELO2
Reference locus (S288C): YCR034W
Gene biotype: protein_coding
Description: Elongation of fatty acids protein 2; Fatty acid elongase, involved in sphingolipid biosynthesis; acts on fatty acids of up to 24 carbons in length; mutations have regulatory effects on 1,3-beta-glucan synthase, vacuolar ATPase, and the secretory pathway; ELO2 has a paralog, ELO1, that arose from the whole genome duplication; lethality of the elo2 elo3 double null mutation is functionally complemented by human ELOVL1 and weakly complemented by human ELOVL3 or ELOV7
Top 10 interactors (score): ELO1 (0.999); ELO3 (0.995); TSC13 (0.993); IFA38 (0.992); PHS1 (0.977); OLE1 (0.974); CEM1 (0.828); VRG4 (0.793); FAS2 (0.772); LAC1 (0.769); IPT1 (0.746); FAS1 (0.725); SUR1 (0.718); CDC27 (0.713); SUR2 (0.71); YDC1 (0.696); MAC1 (0.655); FAT1 (0.654); LAG1 (0.645); TSC10 (0.632)
Homologues (species, bitscore): ELOVL5 (Homo sapiens, 87.4); Elovl5 (Mus musculus, 109.8); elovl2 (Danio rerio, 95.1); elovl5 (Xenopus tropicalis, 89.0); bond (Drosophila melanogaster, 82.8); elo-6 (Caenorhabditis elegans, 94.0); AT3G06460 (Arabidopsis thaliana, 91.3)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005297.1:184056-185099:+ | gene-YCR034W_AKU4011 | rna-NM_001178748.1_AKU4011 | cds-NP_009963.1_AKU4011 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000067.1:38551-39594:+ | gene-YCR034W_BG1 | rna-NM_001178748.1_BG1 | cds-NP_009963.1_BG1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005505.1:180343-181386:+ | gene-YCR034W_Bruggeman | rna-NM_001178748.1_Bruggeman | cds-NP_009963.1_Bruggeman | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005521.1:191485-192528:+ | gene-YCR034W_CAT1 | rna-NM_001178748.1_CAT1 | cds-NP_009963.1_CAT1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005361.1:178817-179860:+ | gene-YCR034W_CBS1585 | rna-NM_001178748.1_CBS1585 | cds-NP_009963.1_CBS1585 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005345.1:190464-191507:+ | gene-YCR034W_CBS436 | rna-NM_001178748.1_CBS436 | cds-NP_009963.1_CBS436 | 99.9 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005329.1:172670-173713:+ | gene-YCR034W_CBS6412 | rna-NM_001178748.1_CBS6412 | cds-NP_009963.1_CBS6412 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005313.1:184994-186037:+ | gene-YCR034W_CBS6413 | rna-NM_001178748.1_CBS6413 | cds-NP_009963.1_CBS6413 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001524.1:189938-190981:+ | gene-YCR034W_CENPK1137D | rna-NM_001178748.1_CENPK1137D | cds-NP_009963.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005473.1:181817-182860:+ | gene-YCR034W_EthanolRed | rna-NM_001178748.1_EthanolRed | cds-NP_009963.1_EthanolRed | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005537.1:184933-185976:+ | gene-YCR034W_FaliES1 | rna-NM_001178748.1_FaliES1 | cds-NP_009963.1_FaliES1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000102.1:21211-22254:+ | gene-YCR034W_JAY291 | rna-NM_001178748.1_JAY291 | cds-NP_009963.1_JAY291 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005409.1:177582-178625:+ | gene-YCR034W_MUCL30387 | rna-NM_001178748.1_MUCL30387 | cds-NP_009963.1_MUCL30387 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005441.1:177373-178416:+ | gene-YCR034W_MUCL30388 | rna-NM_001178748.1_MUCL30388 | cds-NP_009963.1_MUCL30388 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005281.1:185141-186184:+ | gene-YCR034W_MUCL39482 | rna-NM_001178748.1_MUCL39482 | cds-NP_009963.1_MUCL39482 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005425.1:182936-183979:+ | gene-YCR034W_MUCL42920 | rna-NM_001178748.1_MUCL42920 | cds-NP_009963.1_MUCL42920 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011812.1:190224-191267:+ | gene-YCR034W_NCIM3186 | rna-NM_001178748.1_NCIM3186 | cds-NP_009963.1_NCIM3186 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005265.1:186905-187948:+ | gene-YCR034W_NCYC1407 | rna-NM_001178748.1_NCYC1407 | cds-NP_009963.1_NCYC1407 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994142.1:195953-196996:+ | gene-YCR034W_PE2H3 | rna-NM_001178748.1_PE2H3 | cds-NP_009963.1_PE2H3 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999874.1:190572-191615:+ | gene-YCR034W_PE2H4 | rna-NM_001178748.1_PE2H4 | cds-NP_009963.1_PE2H4 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001135.5:190592-191635:+ | gene-YCR034W_S288C | rna-NM_001178748.1_S288C | cds-NP_009963.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000083.1:38101-39144:+ | gene-YCR034W_SA1 | rna-NM_001178748.1_SA1 | cds-NP_009963.1_SA1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005489.1:185709-186752:+ | gene-YCR034W_ThermosaccDry | rna-NM_001178748.1_ThermosaccDry | cds-NP_009963.1_ThermosaccDry | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005457.1:196729-197772:+ | gene-YCR034W_VR1 | rna-NM_001178748.1_VR1 | cds-NP_009963.1_VR1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000004.1:183962-185005:+ | gene-YCR034W_ZTW1 | rna-NM_001178748.1_ZTW1 | cds-NP_009963.1_ZTW1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047489.1:218132-219175:+ | gene-YCR034W_Sparadoxus | rna-NM_001178748.1_Sparadoxus | cds-NP_009963.1_Sparadoxus | 94.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |