Gene name: ELM1
Reference locus (S288C): YKL048C
Gene biotype: protein_coding
Description: Serine/threonine-protein kinase ELM1; Serine/threonine protein kinase; regulates the orientation checkpoint, the morphogenesis checkpoint and the metabolic switch from fermentative to oxidative metabolism by phosphorylating the activation loop of Kin4p, Hsl1p and Snf4p respectively; cooperates with Hsl7p in recruiting Hsl1p to the septin ring, a prerequisite for subsequent recruitment, phosphorylation, and degradation of Swe1p; forms part of the bud neck ring; regulates cytokinesis
Top 10 interactors (score): SAK1 (0.987); TOS3 (0.969); SNF1 (0.955); SIP1 (0.896); GAL83 (0.893); SNF4 (0.892); CDC28 (0.884); MIH1 (0.875); SIP2 (0.874); HSL1 (0.868); SWE1 (0.849); ATG1 (0.833); SHS1 (0.833); BNI5 (0.83); CDC11 (0.829); GIN4 (0.828); GLC7 (0.824); RTS1 (0.814); CDC12 (0.81); HSL7 (0.802)
Homologues (species, bitscore): CAMKK2 (Homo sapiens, 127.1); Camkk1 (Mus musculus, 137.5); camkk1 (Danio rerio, 127.5); camkk2 (Xenopus tropicalis, 131.0); CG17698 (Drosophila melanogaster, 102.1); ckk-1 (Caenorhabditis elegans, 103.6); CIPK16 (Arabidopsis thaliana, 107.1)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005305.1:333215-335137:- | gene-YKL048C_AKU4011 | rna-NM_001179614.1_AKU4011 | cds-NP_012876.1_AKU4011 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000113.1:308872-310794:+ | gene-YKL048C_BG1 | rna-NM_001179614.1_BG1 | cds-NP_012876.1_BG1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005513.1:352241-354163:- | gene-YKL048C_Bruggeman | rna-NM_001179614.1_Bruggeman | cds-NP_012876.1_Bruggeman | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005529.1:348674-350596:- | gene-YKL048C_CAT1 | rna-NM_001179614.1_CAT1 | cds-NP_012876.1_CAT1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005369.1:345946-347868:- | gene-YKL048C_CBS1585 | rna-NM_001179614.1_CBS1585 | cds-NP_012876.1_CBS1585 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005353.1:344074-345996:- | gene-YKL048C_CBS436 | rna-NM_001179614.1_CBS436 | cds-NP_012876.1_CBS436 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005337.1:330079-332001:- | gene-YKL048C_CBS6412 | rna-NM_001179614.1_CBS6412 | cds-NP_012876.1_CBS6412 | 99.5 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005321.1:345907-347829:- | gene-YKL048C_CBS6413 | rna-NM_001179614.1_CBS6413 | cds-NP_012876.1_CBS6413 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001532.1:346873-348795:- | gene-YKL048C_CENPK1137D | rna-NM_001179614.1_CENPK1137D | cds-NP_012876.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005481.1:343901-345823:- | gene-YKL048C_EthanolRed | rna-NM_001179614.1_EthanolRed | cds-NP_012876.1_EthanolRed | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005545.1:344714-346636:- | gene-YKL048C_FaliES1 | rna-NM_001179614.1_FaliES1 | cds-NP_012876.1_FaliES1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000080.1:49637-51559:- | gene-YKL048C_JAY291 | rna-NM_001179614.1_JAY291 | cds-NP_012876.1_JAY291 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005417.1:353142-355064:- | gene-YKL048C_MUCL30387 | rna-NM_001179614.1_MUCL30387 | cds-NP_012876.1_MUCL30387 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005449.1:348031-349953:- | gene-YKL048C_MUCL30388 | rna-NM_001179614.1_MUCL30388 | cds-NP_012876.1_MUCL30388 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005289.1:345242-347164:- | gene-YKL048C_MUCL39482 | rna-NM_001179614.1_MUCL39482 | cds-NP_012876.1_MUCL39482 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005433.1:350098-352020:- | gene-YKL048C_MUCL42920 | rna-NM_001179614.1_MUCL42920 | cds-NP_012876.1_MUCL42920 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011820.1:347203-349125:- | gene-YKL048C_NCIM3186 | rna-NM_001179614.1_NCIM3186 | cds-NP_012876.1_NCIM3186 | 98.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005273.1:345437-347359:- | gene-YKL048C_NCYC1407 | rna-NM_001179614.1_NCYC1407 | cds-NP_012876.1_NCYC1407 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994150.1:369980-371902:- | gene-YKL048C_PE2H3 | rna-NM_001179614.1_PE2H3 | cds-NP_012876.1_PE2H3 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999882.1:354719-356641:- | gene-YKL048C_PE2H4 | rna-NM_001179614.1_PE2H4 | cds-NP_012876.1_PE2H4 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001143.9:347214-349136:- | gene-YKL048C_S288C | rna-NM_001179614.1_S288C | cds-NP_012876.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000027.1:25324-27246:- | gene-YKL048C_SA1 | rna-NM_001179614.1_SA1 | cds-NP_012876.1_SA1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005497.1:345904-347826:- | gene-YKL048C_ThermosaccDry | rna-NM_001179614.1_ThermosaccDry | cds-NP_012876.1_ThermosaccDry | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005465.1:345048-346970:- | gene-YKL048C_VR1 | rna-NM_001179614.1_VR1 | cds-NP_012876.1_VR1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000022.1:343918-345840:- | gene-YKL048C_ZTW1 | rna-NM_001179614.1_ZTW1 | cds-NP_012876.1_ZTW1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047497.1:363183-365105:- | gene-YKL048C_Sparadoxus | rna-NM_001179614.1_Sparadoxus | cds-NP_012876.1_Sparadoxus | 87.4 | 99.9 | Verified | 1 | 1 | 1 | False | True | False | False | False |