ELC1 (YPL046C)


Gene profile

Gene name: ELC1
Reference locus (S288C): YPL046C
Gene biotype: protein_coding

Description: Elongin-C; Elongin C, conserved among eukaryotes; forms a complex with Cul3p that polyubiquitylates monoubiquitylated RNA polymerase II to trigger its proteolysis; plays a role in global genomic repair

Top 10 interactors (score): HRT1 (0.999); ELA1 (0.999); CUL3 (0.999); CDC53 (0.997); RAD7 (0.996); RAD16 (0.977); ASC1 (0.974); RPO21 (0.973); SKP1 (0.963); RRI1 (0.946); PAC10 (0.915); RAD26 (0.888); RSP5 (0.883); BET2 (0.875); PRS1 (0.874); APC11 (0.871); RPB9 (0.854); UBX5 (0.853); UBA3 (0.835); PHO81 (0.835)

Homologues (species, bitscore): TCEB1 (Homo sapiens, 72.0); Tceb1 (Mus musculus, 72.0); tceb1a (Danio rerio, 72.0); tceb1 (Xenopus tropicalis, 72.0); EloC (Drosophila melanogaster, 73.2); elc-1 (Caenorhabditis elegans, 75.9); AT5G59140 (Arabidopsis thaliana, 63.2)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005310.1:438145-438444:- gene-YPL046C_AKU4011 rna-NM_001183860.1_AKU4011 cds-NP_015279.1_AKU4011 100.0 100.0 Verified 1 1 1 True True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000091.1:459002-459301:+ gene-YPL046C_BG1 rna-NM_001183860.1_BG1 cds-NP_015279.1_BG1 100.0 100.0 Verified 1 1 1 True True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005518.1:515085-515384:- gene-YPL046C_Bruggeman rna-NM_001183860.1_Bruggeman cds-NP_015279.1_Bruggeman 99.6 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005534.1:554771-555070:- gene-YPL046C_CAT1 rna-NM_001183860.1_CAT1 cds-NP_015279.1_CAT1 99.6 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005374.1:442213-442512:- gene-YPL046C_CBS1585 rna-NM_001183860.1_CBS1585 cds-NP_015279.1_CBS1585 100.0 100.0 Verified 1 1 1 True True False False False
CBS436 GCA_001738355.1 Sake Asia CM005358.1:456330-456629:- gene-YPL046C_CBS436 rna-NM_001183860.1_CBS436 cds-NP_015279.1_CBS436 99.6 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005342.1:446403-446702:- gene-YPL046C_CBS6412 rna-NM_001183860.1_CBS6412 cds-NP_015279.1_CBS6412 100.0 100.0 Mismatch 1 1 1 True True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005326.1:438764-439063:- gene-YPL046C_CBS6413 rna-NM_001183860.1_CBS6413 cds-NP_015279.1_CBS6413 100.0 100.0 Verified 1 1 1 True True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001537.1:466621-466920:- gene-YPL046C_CENPK1137D rna-NM_001183860.1_CENPK1137D cds-NP_015279.1_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005486.1:436500-436799:- gene-YPL046C_EthanolRed rna-NM_001183860.1_EthanolRed cds-NP_015279.1_EthanolRed 100.0 100.0 Verified 1 1 1 True True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005550.1:444330-444629:- gene-YPL046C_FaliES1 rna-NM_001183860.1_FaliES1 cds-NP_015279.1_FaliES1 100.0 100.0 Verified 1 1 1 True True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000283.1:52921-53220:- gene-YPL046C_JAY291 rna-NM_001183860.1_JAY291 cds-NP_015279.1_JAY291 100.0 100.0 Verified 1 1 1 True True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005422.1:456019-456318:- gene-YPL046C_MUCL30387 rna-NM_001183860.1_MUCL30387 cds-NP_015279.1_MUCL30387 99.6 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005454.1:455160-455459:- gene-YPL046C_MUCL30388 rna-NM_001183860.1_MUCL30388 cds-NP_015279.1_MUCL30388 100.0 100.0 Verified 1 1 1 True True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005294.1:435529-435828:- gene-YPL046C_MUCL39482 rna-NM_001183860.1_MUCL39482 cds-NP_015279.1_MUCL39482 100.0 100.0 Verified 1 1 1 True True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005438.1:494123-494422:- gene-YPL046C_MUCL42920 rna-NM_001183860.1_MUCL42920 cds-NP_015279.1_MUCL42920 99.6 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011825.1:466627-466926:- gene-YPL046C_NCIM3186 rna-NM_001183860.1_NCIM3186 cds-NP_015279.1_NCIM3186 99.6 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005278.1:442807-443106:- gene-YPL046C_NCYC1407 rna-NM_001183860.1_NCYC1407 cds-NP_015279.1_NCYC1407 100.0 100.0 Verified 1 1 1 True True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994155.1:449415-449714:- gene-YPL046C_PE2H3 rna-NM_001183860.1_PE2H3 cds-NP_015279.1_PE2H3 100.0 100.0 Verified 1 1 1 True True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999887.1:449030-449329:- gene-YPL046C_PE2H4 rna-NM_001183860.1_PE2H4 cds-NP_015279.1_PE2H4 100.0 100.0 Verified 1 1 1 True True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001148.4:466644-466943:- gene-YPL046C_S288C rna-NM_001183860.1_S288C cds-NP_015279.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000077.1:4472-4771:- gene-YPL046C_SA1 rna-NM_001183860.1_SA1 cds-NP_015279.1_SA1 99.6 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005502.1:444129-444428:- gene-YPL046C_ThermosaccDry rna-NM_001183860.1_ThermosaccDry cds-NP_015279.1_ThermosaccDry 100.0 100.0 Verified 1 1 1 True True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005470.1:458946-459245:- gene-YPL046C_VR1 rna-NM_001183860.1_VR1 cds-NP_015279.1_VR1 100.0 100.0 Verified 1 1 1 True True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000033.1:443431-443730:- gene-YPL046C_ZTW1 rna-NM_001183860.1_ZTW1 cds-NP_015279.1_ZTW1 100.0 100.0 Verified 1 1 1 True True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047502.1:444055-444354:- gene-YPL046C_Sparadoxus rna-NM_001183860.1_Sparadoxus cds-NP_015279.1_Sparadoxus 88.0 100.0 Verified 1 1 1 False True False False False

Additional files