Gene name: EFT2
Reference locus (S288C): YDR385W
Gene biotype: protein_coding
Description: Elongation factor 2 (EF-2), also encoded by EFT1; catalyzes ribosomal translocation during protein synthesis; contains diphthamide, the unique posttranslationally modified histidine residue specifically ADP-ribosylated by diphtheria toxin; EFT2 has a paralog, EFT1, that arose from the whole genome duplication
Top 10 interactors (score): RPS13 (0.999); RPL2A (0.999); RPL32 (0.999); RPP2A (0.999); RPL3 (0.999); RPL4B (0.999); RPS2 (0.999); RPS3 (0.999); RPS0A (0.999); RPL10 (0.999); ASC1 (0.999); RPS20 (0.999); RPL25 (0.999); RPL5 (0.999); RPS5 (0.999); RPP1A (0.999); RPS15 (0.999); RPL28 (0.999); RPP0 (0.999); RPL2B (0.998)
Homologues (species, bitscore): EEF2 (Homo sapiens, 1186.4); Eef2 (Mus musculus, 1185.6); eef2l2 (Danio rerio, 1187.9); eef2.2 (Xenopus tropicalis, 1189.5); EF2 (Drosophila melanogaster, 1184.5); eef-2 (Caenorhabditis elegans, 1187.2); LOS1 (Arabidopsis thaliana, 1097.8)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005309.1:578584-581080:+ | gene-YDR385W_AKU4011 | rna-NM_001180693.1_AKU4011 | cds-NP_010673.1_AKU4011 | 98.4 | 98.7 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000039.1:61855-64383:+ | gene-YDR385W_BG1 | rna-NM_001180693.1_BG1 | cds-NP_010673.1_BG1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005506.1:1214256-1216784:+ | gene-YDR385W_Bruggeman | rna-NM_001180693.1_Bruggeman | cds-NP_010673.1_Bruggeman | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005522.1:1192862-1195390:+ | gene-YDR385W_CAT1 | rna-NM_001180693.1_CAT1 | cds-NP_010673.1_CAT1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005362.1:1178082-1180610:+ | gene-YDR385W_CBS1585 | rna-NM_001180693.1_CBS1585 | cds-NP_010673.1_CBS1585 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005346.1:1196910-1199438:+ | gene-YDR385W_CBS436 | rna-NM_001180693.1_CBS436 | cds-NP_010673.1_CBS436 | 99.9 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001525.1:1241879-1244407:+ | gene-YDR385W_CENPK1137D | rna-NM_001180693.1_CENPK1137D | cds-NP_010673.1_CENPK1137D | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005410.1:1197569-1200346:+ | gene-YDR385W_MUCL30387 | rna-NM_001180693.1_MUCL30387 | cds-NP_010673.1_MUCL30387 | 91.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011813.1:1243153-1245681:+ | gene-YDR385W_NCIM3186 | rna-NM_001180693.1_NCIM3186 | cds-NP_010673.1_NCIM3186 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994143.1:1193718-1196246:+ | gene-YDR385W_PE2H3 | rna-NM_001180693.1_PE2H3 | cds-NP_010673.1_PE2H3 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999875.1:1199292-1201820:+ | gene-YDR385W_PE2H4 | rna-NM_001180693.1_PE2H4 | cds-NP_010673.1_PE2H4 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001136.10:1243230-1245758:+ | gene-YDR385W_S288C | rna-NM_001180693.1_S288C | cds-NP_010673.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000158.1:4-2532:- | gene-YDR385W_SA1 | rna-NM_001180693.1_SA1 | cds-NP_010673.1_SA1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005469.1:622636-625100:+ | gene-YDR385W_VR1 | rna-NM_001180693.1_VR1 | cds-NP_010673.1_VR1 | 97.4 | 97.4 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000008.1:238160-240688:+ | gene-YDR385W_ZTW1 | rna-NM_001180693.1_ZTW1 | cds-NP_010673.1_ZTW1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047490.1:1189937-1192465:+ | gene-YDR385W_Sparadoxus | rna-NM_001180693.1_Sparadoxus | cds-NP_010673.1_Sparadoxus | 96.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |