Gene name: EFT1
Reference locus (S288C): YOR133W
Gene biotype: protein_coding
Description: Elongation factor 2 (EF-2), also encoded by EFT2; catalyzes ribosomal translocation during protein synthesis; contains diphthamide, the unique posttranslationally modified histidine residue specifically ADP-ribosylated by diphtheria toxin; EFT1 has a paralog, EFT2, that arose from the whole genome duplication
Top 10 interactors (score): RPL4B (0.999); TMA19 (0.999); RPS4A (0.999); RPP2B (0.999); RPS3 (0.999); RPS2 (0.999); RPL10 (0.999); ASC1 (0.999); RPS0A (0.999); RPL25 (0.999); RPS20 (0.999); RPS5 (0.999); RPL5 (0.999); RPL28 (0.999); RPS15 (0.999); RPS8A (0.999); RPL2A (0.999); RPS13 (0.999); RPP2A (0.999); RPL32 (0.999)
Homologues (species, bitscore): EEF2 (Homo sapiens, 1186.4); Eef2 (Mus musculus, 1185.6); eef2l2 (Danio rerio, 1187.9); eef2.2 (Xenopus tropicalis, 1189.5); EF2 (Drosophila melanogaster, 1184.5); eef-2 (Caenorhabditis elegans, 1187.2); LOS1 (Arabidopsis thaliana, 1097.8)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000171.1:17574-20102:- | gene-YOR133W_BG1 | rna-NM_001183552.1_BG1 | cds-NP_014776.1_BG1 | 99.7 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | MBVQ01000040.1:4-2532:- | gene-YOR133W_CBS6412 | rna-NM_001183552.1_CBS6412 | cds-NP_014776.1_CBS6412 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005325.1:560761-563289:+ | gene-YOR133W_CBS6413 | rna-NM_001183552.1_CBS6413 | cds-NP_014776.1_CBS6413 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | MBWB01000044.1:1-2405:- | gene-YOR133W_EthanolRed | rna-NM_001183552.1_EthanolRed | cds-NP_014776.1_EthanolRed | 94.9 | 95.0 | Mismatch | 1 | 1 | 0 | False | False | False | True | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005549.1:559482-561944:+ | gene-YOR133W_FaliES1 | rna-NM_001183552.1_FaliES1 | cds-NP_014776.1_FaliES1 | 96.2 | 97.3 | Mismatch | 1 | 1 | 0 | False | False | False | True | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000070.1:81307-83835:- | gene-YOR133W_JAY291 | rna-NM_001183552.1_JAY291 | cds-NP_014776.1_JAY291 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005453.1:572724-575252:+ | gene-YOR133W_MUCL30388 | rna-NM_001183552.1_MUCL30388 | cds-NP_014776.1_MUCL30388 | 99.9 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005293.1:562862-565390:+ | gene-YOR133W_MUCL39482 | rna-NM_001183552.1_MUCL39482 | cds-NP_014776.1_MUCL39482 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005437.1:578399-580927:+ | gene-YOR133W_MUCL42920 | rna-NM_001183552.1_MUCL42920 | cds-NP_014776.1_MUCL42920 | 99.9 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011824.1:574987-577515:+ | gene-YOR133W_NCIM3186 | rna-NM_001183552.1_NCIM3186 | cds-NP_014776.1_NCIM3186 | 99.9 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005277.1:568821-571349:+ | gene-YOR133W_NCYC1407 | rna-NM_001183552.1_NCYC1407 | cds-NP_014776.1_NCYC1407 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994154.1:567574-570102:+ | gene-YOR133W_PE2H3 | rna-NM_001183552.1_PE2H3 | cds-NP_014776.1_PE2H3 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999886.1:577951-580479:+ | gene-YOR133W_PE2H4 | rna-NM_001183552.1_PE2H4 | cds-NP_014776.1_PE2H4 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001147.6:575098-577626:+ | gene-YOR133W_S288C | rna-NM_001183552.1_S288C | cds-NP_014776.1_S288C | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005501.1:558665-561127:+ | gene-YOR133W_ThermosaccDry | rna-NM_001183552.1_ThermosaccDry | cds-NP_014776.1_ThermosaccDry | 96.2 | 97.3 | Mismatch | 1 | 1 | 0 | False | False | False | True | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000032.1:292348-294876:+ | gene-YOR133W_ZTW1 | rna-NM_001183552.1_ZTW1 | cds-NP_014776.1_ZTW1 | 99.9 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047501.1:563789-566317:+ | gene-YOR133W_Sparadoxus | rna-NM_001183552.1_Sparadoxus | cds-NP_014776.1_Sparadoxus | 97.0 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |