Gene name: EFR3
Reference locus (S288C): YMR212C
Gene biotype: protein_coding
Description: Protein required for Stt4-containing PI kinase complex localization; required for Stt4-containing phosphoinositide (PI) kinase patch assembly at the plasma membrane; recruited to the plasma membrane via a conserved basic patch near its N-terminus; exhibits synthetic lethal genetic interactions with PHO85; has sequence similarity to the Drosophila rolling blackout (RBO) gene
Top 10 interactors (score): STT4 (0.997); YPP1 (0.993); MSS4 (0.914); PIK1 (0.897); SFK1 (0.856); OSH3 (0.81); SAC1 (0.78); OSH2 (0.7); VID27 (0.659); FAB1 (0.639); ENT3 (0.6); PHO85 (0.599); PXL1 (0.598); BYE1 (0.572); EPO1 (0.571); ECM13 (0.569); SKI3 (0.568); SDS23 (0.531); CDC42 (0.523); LSB6 (0.52)
Homologues (species, bitscore): efr3a (Danio rerio, 51.6); efr3a (Xenopus tropicalis, 51.2); stmA (Drosophila melanogaster, 50.8)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005307.1:730618-732966:- | gene-YMR212C_AKU4011 | rna-NM_001182719.1_AKU4011 | cds-NP_013939.1_AKU4011 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000069.1:221641-223989:+ | gene-YMR212C_BG1 | rna-NM_001182719.1_BG1 | cds-NP_013939.1_BG1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005515.1:674831-677179:- | gene-YMR212C_Bruggeman | rna-NM_001182719.1_Bruggeman | cds-NP_013939.1_Bruggeman | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005531.1:678088-680436:- | gene-YMR212C_CAT1 | rna-NM_001182719.1_CAT1 | cds-NP_013939.1_CAT1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005371.1:662880-665228:- | gene-YMR212C_CBS1585 | rna-NM_001182719.1_CBS1585 | cds-NP_013939.1_CBS1585 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005355.1:667132-669480:- | gene-YMR212C_CBS436 | rna-NM_001182719.1_CBS436 | cds-NP_013939.1_CBS436 | 99.9 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005339.1:774437-776785:- | gene-YMR212C_CBS6412 | rna-NM_001182719.1_CBS6412 | cds-NP_013939.1_CBS6412 | 99.3 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005323.1:662028-664376:- | gene-YMR212C_CBS6413 | rna-NM_001182719.1_CBS6413 | cds-NP_013939.1_CBS6413 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001534.1:685416-687764:- | gene-YMR212C_CENPK1137D | rna-NM_001182719.1_CENPK1137D | cds-NP_013939.1_CENPK1137D | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005486.1:723084-725432:- | gene-YMR212C_EthanolRed | rna-NM_001182719.1_EthanolRed | cds-NP_013939.1_EthanolRed | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005547.1:668736-671084:- | gene-YMR212C_FaliES1 | rna-NM_001182719.1_FaliES1 | cds-NP_013939.1_FaliES1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000141.1:114953-117301:+ | gene-YMR212C_JAY291 | rna-NM_001182719.1_JAY291 | cds-NP_013939.1_JAY291 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005419.1:668379-670727:- | gene-YMR212C_MUCL30387 | rna-NM_001182719.1_MUCL30387 | cds-NP_013939.1_MUCL30387 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005451.1:675158-677506:- | gene-YMR212C_MUCL30388 | rna-NM_001182719.1_MUCL30388 | cds-NP_013939.1_MUCL30388 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005291.1:663950-666298:- | gene-YMR212C_MUCL39482 | rna-NM_001182719.1_MUCL39482 | cds-NP_013939.1_MUCL39482 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005435.1:671273-673621:- | gene-YMR212C_MUCL42920 | rna-NM_001182719.1_MUCL42920 | cds-NP_013939.1_MUCL42920 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011822.1:690649-692997:- | gene-YMR212C_NCIM3186 | rna-NM_001182719.1_NCIM3186 | cds-NP_013939.1_NCIM3186 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005275.1:663602-665950:- | gene-YMR212C_NCYC1407 | rna-NM_001182719.1_NCYC1407 | cds-NP_013939.1_NCYC1407 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994152.1:673449-675797:- | gene-YMR212C_PE2H3 | rna-NM_001182719.1_PE2H3 | cds-NP_013939.1_PE2H3 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999884.1:674464-676812:- | gene-YMR212C_PE2H4 | rna-NM_001182719.1_PE2H4 | cds-NP_013939.1_PE2H4 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001145.3:690695-693043:- | gene-YMR212C_S288C | rna-NM_001182719.1_S288C | cds-NP_013939.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000002.1:115064-117412:+ | gene-YMR212C_SA1 | rna-NM_001182719.1_SA1 | cds-NP_013939.1_SA1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005499.1:664907-667255:- | gene-YMR212C_ThermosaccDry | rna-NM_001182719.1_ThermosaccDry | cds-NP_013939.1_ThermosaccDry | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005467.1:677975-680323:- | gene-YMR212C_VR1 | rna-NM_001182719.1_VR1 | cds-NP_013939.1_VR1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000028.1:80611-82959:- | gene-YMR212C_ZTW1 | rna-NM_001182719.1_ZTW1 | cds-NP_013939.1_ZTW1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047499.1:682677-685025:- | gene-YMR212C_Sparadoxus | rna-NM_001182719.1_Sparadoxus | cds-NP_013939.1_Sparadoxus | 90.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |