Gene name: EFM6
Reference locus (S288C): YNL024C
Gene biotype: protein_coding
Description: Protein-lysine N-methyltransferase EFM6; Putative S-adenosylmethionine-dependent lysine methyltransferase; responsible for modifying Lys-390 in translational elongation factor EF-1 alpha (eEF1A); has seven beta-strand methyltransferase motif; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm
Top 10 interactors (score): CDC48 (0.985); EFM5 (0.956); EFM4 (0.931); SSA3 (0.928); SSA1 (0.925); SSA2 (0.916); SSA4 (0.915); HPM1 (0.905); NNT1 (0.886); EFM1 (0.782); BSC6 (0.717); TAE1 (0.702); YIR014W (0.698); FLC3 (0.697); RCM1 (0.693); YGR283C (0.69); BMT6 (0.678); RTS2 (0.676); BMT2 (0.664); FMP46 (0.651)
Homologues (species, bitscore): METTL21A (Homo sapiens, 87.0); Mettl21a (Mus musculus, 85.9); mettl21a (Danio rerio, 88.6); mettl21a (Xenopus tropicalis, 87.0); CG10584 (Drosophila melanogaster, 58.9); AT1G73320 (Arabidopsis thaliana, 63.9)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
AKU4011 | GCA_001738255.1 | Sake | Asia | CM005308.1:569566-570306:- | gene-YNL024C_AKU4011 | rna-NM_001182863.1_AKU4011 | cds-NP_014374.1_AKU4011 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000155.1:469837-470577:+ | gene-YNL024C_BG1 | rna-NM_001182863.1_BG1 | cds-NP_014374.1_BG1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005516.1:586987-587727:- | gene-YNL024C_Bruggeman | rna-NM_001182863.1_Bruggeman | cds-NP_014374.1_Bruggeman | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005532.1:622436-623176:- | gene-YNL024C_CAT1 | rna-NM_001182863.1_CAT1 | cds-NP_014374.1_CAT1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
CBS1585 | GCA_001738375.1 | Sake | Asia | CM005372.1:575250-575990:- | gene-YNL024C_CBS1585 | rna-NM_001182863.1_CBS1585 | cds-NP_014374.1_CBS1585 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
CBS436 | GCA_001738355.1 | Sake | Asia | CM005356.1:637661-638401:- | gene-YNL024C_CBS436 | rna-NM_001182863.1_CBS436 | cds-NP_014374.1_CBS436 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
CBS6412 | GCA_001738345.1 | Sake | Asia | CM005340.1:565083-565823:- | gene-YNL024C_CBS6412 | rna-NM_001182863.1_CBS6412 | cds-NP_014374.1_CBS6412 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
CBS6413 | GCA_001738265.1 | Sake | Asia | CM005324.1:566424-567164:- | gene-YNL024C_CBS6413 | rna-NM_001182863.1_CBS6413 | cds-NP_014374.1_CBS6413 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001535.1:580714-581454:- | gene-YNL024C_CENPK1137D | rna-NM_001182863.1_CENPK1137D | cds-NP_014374.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005484.1:571652-572392:- | gene-YNL024C_EthanolRed | rna-NM_001182863.1_EthanolRed | cds-NP_014374.1_EthanolRed | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005548.1:562676-563416:- | gene-YNL024C_FaliES1 | rna-NM_001182863.1_FaliES1 | cds-NP_014374.1_FaliES1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000387.1:10418-11158:+ | gene-YNL024C_JAY291 | rna-NM_001182863.1_JAY291 | cds-NP_014374.1_JAY291 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005420.1:582869-583609:- | gene-YNL024C_MUCL30387 | rna-NM_001182863.1_MUCL30387 | cds-NP_014374.1_MUCL30387 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005452.1:625663-626403:- | gene-YNL024C_MUCL30388 | rna-NM_001182863.1_MUCL30388 | cds-NP_014374.1_MUCL30388 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005292.1:566845-567585:- | gene-YNL024C_MUCL39482 | rna-NM_001182863.1_MUCL39482 | cds-NP_014374.1_MUCL39482 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005436.1:570404-571144:- | gene-YNL024C_MUCL42920 | rna-NM_001182863.1_MUCL42920 | cds-NP_014374.1_MUCL42920 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011823.1:587076-587816:- | gene-YNL024C_NCIM3186 | rna-NM_001182863.1_NCIM3186 | cds-NP_014374.1_NCIM3186 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005276.1:569050-569790:- | gene-YNL024C_NCYC1407 | rna-NM_001182863.1_NCYC1407 | cds-NP_014374.1_NCYC1407 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994153.1:571574-572314:- | gene-YNL024C_PE2H3 | rna-NM_001182863.1_PE2H3 | cds-NP_014374.1_PE2H3 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999885.1:572892-573632:- | gene-YNL024C_PE2H4 | rna-NM_001182863.1_PE2H4 | cds-NP_014374.1_PE2H4 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001146.8:587107-587847:- | gene-YNL024C_S288C | rna-NM_001182863.1_S288C | cds-NP_014374.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000109.1:13133-13873:- | gene-YNL024C_SA1 | rna-NM_001182863.1_SA1 | cds-NP_014374.1_SA1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005500.1:563263-564003:- | gene-YNL024C_ThermosaccDry | rna-NM_001182863.1_ThermosaccDry | cds-NP_014374.1_ThermosaccDry | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
VR1 | GCA_001738595.1 | Bioethanol | South America | CM005468.1:578747-579487:+ | gene-YNL024C_VR1 | rna-NM_001182863.1_VR1 | cds-NP_014374.1_VR1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000030.1:469437-470177:+ | gene-YNL024C_ZTW1 | rna-NM_001182863.1_ZTW1 | cds-NP_014374.1_ZTW1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047500.1:578354-579094:- | gene-YNL024C_Sparadoxus | rna-NM_001182863.1_Sparadoxus | cds-NP_014374.1_Sparadoxus | 91.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |