EFM6 (YNL024C)


Gene profile

Gene name: EFM6
Reference locus (S288C): YNL024C
Gene biotype: protein_coding

Description: Protein-lysine N-methyltransferase EFM6; Putative S-adenosylmethionine-dependent lysine methyltransferase; responsible for modifying Lys-390 in translational elongation factor EF-1 alpha (eEF1A); has seven beta-strand methyltransferase motif; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm

Top 10 interactors (score): CDC48 (0.985); EFM5 (0.956); EFM4 (0.931); SSA3 (0.928); SSA1 (0.925); SSA2 (0.916); SSA4 (0.915); HPM1 (0.905); NNT1 (0.886); EFM1 (0.782); BSC6 (0.717); TAE1 (0.702); YIR014W (0.698); FLC3 (0.697); RCM1 (0.693); YGR283C (0.69); BMT6 (0.678); RTS2 (0.676); BMT2 (0.664); FMP46 (0.651)

Homologues (species, bitscore): METTL21A (Homo sapiens, 87.0); Mettl21a (Mus musculus, 85.9); mettl21a (Danio rerio, 88.6); mettl21a (Xenopus tropicalis, 87.0); CG10584 (Drosophila melanogaster, 58.9); AT1G73320 (Arabidopsis thaliana, 63.9)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005308.1:569566-570306:- gene-YNL024C_AKU4011 rna-NM_001182863.1_AKU4011 cds-NP_014374.1_AKU4011 99.8 100.0 Verified 1 1 1 True True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000155.1:469837-470577:+ gene-YNL024C_BG1 rna-NM_001182863.1_BG1 cds-NP_014374.1_BG1 99.8 100.0 Verified 1 1 1 True True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005516.1:586987-587727:- gene-YNL024C_Bruggeman rna-NM_001182863.1_Bruggeman cds-NP_014374.1_Bruggeman 99.5 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005532.1:622436-623176:- gene-YNL024C_CAT1 rna-NM_001182863.1_CAT1 cds-NP_014374.1_CAT1 99.8 100.0 Verified 1 1 1 True True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005372.1:575250-575990:- gene-YNL024C_CBS1585 rna-NM_001182863.1_CBS1585 cds-NP_014374.1_CBS1585 99.8 100.0 Verified 1 1 1 True True False False False
CBS436 GCA_001738355.1 Sake Asia CM005356.1:637661-638401:- gene-YNL024C_CBS436 rna-NM_001182863.1_CBS436 cds-NP_014374.1_CBS436 99.8 100.0 Mismatch 1 1 1 True True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005340.1:565083-565823:- gene-YNL024C_CBS6412 rna-NM_001182863.1_CBS6412 cds-NP_014374.1_CBS6412 99.8 100.0 Mismatch 1 1 1 True True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005324.1:566424-567164:- gene-YNL024C_CBS6413 rna-NM_001182863.1_CBS6413 cds-NP_014374.1_CBS6413 99.8 100.0 Verified 1 1 1 True True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001535.1:580714-581454:- gene-YNL024C_CENPK1137D rna-NM_001182863.1_CENPK1137D cds-NP_014374.1_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005484.1:571652-572392:- gene-YNL024C_EthanolRed rna-NM_001182863.1_EthanolRed cds-NP_014374.1_EthanolRed 99.8 100.0 Verified 1 1 1 True True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005548.1:562676-563416:- gene-YNL024C_FaliES1 rna-NM_001182863.1_FaliES1 cds-NP_014374.1_FaliES1 99.8 100.0 Verified 1 1 1 True True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000387.1:10418-11158:+ gene-YNL024C_JAY291 rna-NM_001182863.1_JAY291 cds-NP_014374.1_JAY291 99.8 100.0 Verified 1 1 1 True True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005420.1:582869-583609:- gene-YNL024C_MUCL30387 rna-NM_001182863.1_MUCL30387 cds-NP_014374.1_MUCL30387 99.5 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005452.1:625663-626403:- gene-YNL024C_MUCL30388 rna-NM_001182863.1_MUCL30388 cds-NP_014374.1_MUCL30388 99.8 100.0 Verified 1 1 1 True True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005292.1:566845-567585:- gene-YNL024C_MUCL39482 rna-NM_001182863.1_MUCL39482 cds-NP_014374.1_MUCL39482 99.8 100.0 Verified 1 1 1 True True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005436.1:570404-571144:- gene-YNL024C_MUCL42920 rna-NM_001182863.1_MUCL42920 cds-NP_014374.1_MUCL42920 99.5 100.0 Verified 1 1 1 True True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011823.1:587076-587816:- gene-YNL024C_NCIM3186 rna-NM_001182863.1_NCIM3186 cds-NP_014374.1_NCIM3186 99.5 100.0 Verified 1 1 1 True True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005276.1:569050-569790:- gene-YNL024C_NCYC1407 rna-NM_001182863.1_NCYC1407 cds-NP_014374.1_NCYC1407 99.8 100.0 Verified 1 1 1 True True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994153.1:571574-572314:- gene-YNL024C_PE2H3 rna-NM_001182863.1_PE2H3 cds-NP_014374.1_PE2H3 99.8 100.0 Verified 1 1 1 True True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999885.1:572892-573632:- gene-YNL024C_PE2H4 rna-NM_001182863.1_PE2H4 cds-NP_014374.1_PE2H4 99.8 100.0 Verified 1 1 1 True True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001146.8:587107-587847:- gene-YNL024C_S288C rna-NM_001182863.1_S288C cds-NP_014374.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000109.1:13133-13873:- gene-YNL024C_SA1 rna-NM_001182863.1_SA1 cds-NP_014374.1_SA1 99.8 100.0 Verified 1 1 1 True True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005500.1:563263-564003:- gene-YNL024C_ThermosaccDry rna-NM_001182863.1_ThermosaccDry cds-NP_014374.1_ThermosaccDry 99.8 100.0 Verified 1 1 1 True True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005468.1:578747-579487:+ gene-YNL024C_VR1 rna-NM_001182863.1_VR1 cds-NP_014374.1_VR1 99.8 100.0 Verified 1 1 1 True True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000030.1:469437-470177:+ gene-YNL024C_ZTW1 rna-NM_001182863.1_ZTW1 cds-NP_014374.1_ZTW1 99.8 100.0 Verified 1 1 1 True True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047500.1:578354-579094:- gene-YNL024C_Sparadoxus rna-NM_001182863.1_Sparadoxus cds-NP_014374.1_Sparadoxus 91.4 100.0 Verified 1 1 1 False True False False False

Additional files