Gene name: EFM4
Reference locus (S288C): YIL064W
Gene biotype: protein_coding
Description: Protein-lysine N-methyltransferase EFM4; Lysine methyltransferase; involved in the dimethylation of eEF1A (Tef1p/Tef2p) at lysine 316; sequence similarity to S-adenosylmethionine-dependent methyltransferases of the seven beta-strand family; role in vesicular transport; Belongs to the class I-like SAM-binding methyltransferase superfamily. EFM4 family
Top 10 interactors (score): EFM5 (0.981); EFM3 (0.976); HPM1 (0.975); TEF1 (0.975); EFM2 (0.967); CTF18 (0.962); HSE1 (0.962); EFM1 (0.952); RKM1 (0.95); TAE1 (0.936); EFM6 (0.931); RKM2 (0.928); BMT2 (0.905); SKI7 (0.9); HBS1 (0.9); MTQ1 (0.896); RKM5 (0.894); BMT5 (0.878); NNT1 (0.876); YNL092W (0.863)
Homologues (species, bitscore): METTL10 (Homo sapiens, 113.2); Mettl10 (Mus musculus, 129.4); mettl10 (Danio rerio, 137.5); METTL10 (Xenopus tropicalis, 133.7); CG9643 (Drosophila melanogaster, 137.9); F29B9.1 (Caenorhabditis elegans, 119.8); AR401 (Arabidopsis thaliana, 106.3)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005303.1:238611-239384:+ | gene-YIL064W_AKU4011 | rna-NM_001179414.1_AKU4011 | cds-NP_012200.1_AKU4011 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000164.1:100540-101313:+ | gene-YIL064W_BG1 | rna-NM_001179414.1_BG1 | cds-NP_012200.1_BG1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005511.1:244026-244799:+ | gene-YIL064W_Bruggeman | rna-NM_001179414.1_Bruggeman | cds-NP_012200.1_Bruggeman | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005527.1:234301-235074:+ | gene-YIL064W_CAT1 | rna-NM_001179414.1_CAT1 | cds-NP_012200.1_CAT1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005367.1:238182-238955:+ | gene-YIL064W_CBS1585 | rna-NM_001179414.1_CBS1585 | cds-NP_012200.1_CBS1585 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005351.1:234229-235002:+ | gene-YIL064W_CBS436 | rna-NM_001179414.1_CBS436 | cds-NP_012200.1_CBS436 | 99.4 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005335.1:235557-236330:+ | gene-YIL064W_CBS6412 | rna-NM_001179414.1_CBS6412 | cds-NP_012200.1_CBS6412 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005319.1:230102-230875:+ | gene-YIL064W_CBS6413 | rna-NM_001179414.1_CBS6413 | cds-NP_012200.1_CBS6413 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001530.1:233992-234765:+ | gene-YIL064W_CENPK1137D | rna-NM_001179414.1_CENPK1137D | cds-NP_012200.1_CENPK1137D | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005479.1:222909-223682:+ | gene-YIL064W_EthanolRed | rna-NM_001179414.1_EthanolRed | cds-NP_012200.1_EthanolRed | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005543.1:239812-240585:+ | gene-YIL064W_FaliES1 | rna-NM_001179414.1_FaliES1 | cds-NP_012200.1_FaliES1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000365.1:57548-58321:- | gene-YIL064W_JAY291 | rna-NM_001179414.1_JAY291 | cds-NP_012200.1_JAY291 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005415.1:242246-243019:+ | gene-YIL064W_MUCL30387 | rna-NM_001179414.1_MUCL30387 | cds-NP_012200.1_MUCL30387 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005447.1:238851-239624:+ | gene-YIL064W_MUCL30388 | rna-NM_001179414.1_MUCL30388 | cds-NP_012200.1_MUCL30388 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005287.1:239028-239801:+ | gene-YIL064W_MUCL39482 | rna-NM_001179414.1_MUCL39482 | cds-NP_012200.1_MUCL39482 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005431.1:242392-243165:+ | gene-YIL064W_MUCL42920 | rna-NM_001179414.1_MUCL42920 | cds-NP_012200.1_MUCL42920 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011818.1:241943-242716:+ | gene-YIL064W_NCIM3186 | rna-NM_001179414.1_NCIM3186 | cds-NP_012200.1_NCIM3186 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005271.1:243304-244077:+ | gene-YIL064W_NCYC1407 | rna-NM_001179414.1_NCYC1407 | cds-NP_012200.1_NCYC1407 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994148.1:237284-238057:+ | gene-YIL064W_PE2H3 | rna-NM_001179414.1_PE2H3 | cds-NP_012200.1_PE2H3 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999880.1:231999-232772:+ | gene-YIL064W_PE2H4 | rna-NM_001179414.1_PE2H4 | cds-NP_012200.1_PE2H4 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001141.2:241943-242716:+ | gene-YIL064W_S288C | rna-NM_001179414.1_S288C | cds-NP_012200.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000031.1:83125-83898:- | gene-YIL064W_SA1 | rna-NM_001179414.1_SA1 | cds-NP_012200.1_SA1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005495.1:238475-239248:+ | gene-YIL064W_ThermosaccDry | rna-NM_001179414.1_ThermosaccDry | cds-NP_012200.1_ThermosaccDry | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005463.1:236158-236931:+ | gene-YIL064W_VR1 | rna-NM_001179414.1_VR1 | cds-NP_012200.1_VR1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000019.1:212737-213510:+ | gene-YIL064W_ZTW1 | rna-NM_001179414.1_ZTW1 | cds-NP_012200.1_ZTW1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047495.1:236823-237595:+ | gene-YIL064W_Sparadoxus | rna-NM_001179414.1_Sparadoxus | cds-NP_012200.1_Sparadoxus | 90.6 | 99.8 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |