EDC2 (YER035W)


Gene profile

Gene name: EDC2
Reference locus (S288C): YER035W
Gene biotype: protein_coding

Description: Enhancer of mRNA-decapping protein 2; RNA-binding protein that directly activates mRNA decapping; binds mRNA substrate and enhances activity of decapping proteins Dcp1p and Dcp2p; has a role in translation during heat stress; protein increases in abundance and relocalizes to nucleolus and to nuclear foci upon DNA replication stress; EDC2 has a paralog, EDC1, that arose from the whole genome duplication

Top 10 interactors (score): EDC3 (0.946); EDC1 (0.939); DHH1 (0.897); DCP2 (0.895); DCP1 (0.893); LSM1 (0.779); DCS1 (0.769); SCD6 (0.749); XRN1 (0.747); YJL144W (0.732); YRA1 (0.682); UPF3 (0.656); NAM7 (0.655); CDC39 (0.618); NMD2 (0.614); HSP42 (0.609); KRI1 (0.601); MAK5 (0.6); LSM2 (0.599); TMC1 (0.593)

Homologues (species, bitscore): Unknown

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005299.1:216669-217106:+ gene-YER035W_AKU4011 rna-NM_001178926.3_AKU4011 cds-NP_010952.3_AKU4011 99.0 100.0 Verified 1 1 1 True True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000011.1:208619-209056:- gene-YER035W_BG1 rna-NM_001178926.3_BG1 cds-NP_010952.3_BG1 100.0 100.0 Verified 1 1 1 True True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005507.1:225557-225994:+ gene-YER035W_Bruggeman rna-NM_001178926.3_Bruggeman cds-NP_010952.3_Bruggeman 99.5 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005523.1:219691-220128:+ gene-YER035W_CAT1 rna-NM_001178926.3_CAT1 cds-NP_010952.3_CAT1 100.0 100.0 Verified 1 1 1 True True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005363.1:216594-217031:+ gene-YER035W_CBS1585 rna-NM_001178926.3_CBS1585 cds-NP_010952.3_CBS1585 99.0 100.0 Verified 1 1 1 True True False False False
CBS436 GCA_001738355.1 Sake Asia CM005347.1:218541-218978:+ gene-YER035W_CBS436 rna-NM_001178926.3_CBS436 cds-NP_010952.3_CBS436 100.0 100.0 Mismatch 1 1 1 True True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005331.1:216836-217273:+ gene-YER035W_CBS6412 rna-NM_001178926.3_CBS6412 cds-NP_010952.3_CBS6412 99.0 100.0 Mismatch 1 1 1 True True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005315.1:222079-222516:+ gene-YER035W_CBS6413 rna-NM_001178926.3_CBS6413 cds-NP_010952.3_CBS6413 98.8 100.0 Verified 1 1 1 True True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001526.1:220576-221013:+ gene-YER035W_CENPK1137D rna-NM_001178926.3_CENPK1137D cds-NP_010952.3_CENPK1137D 99.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005475.1:217297-217734:+ gene-YER035W_EthanolRed rna-NM_001178926.3_EthanolRed cds-NP_010952.3_EthanolRed 99.0 100.0 Verified 1 1 1 True True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005539.1:217562-217999:+ gene-YER035W_FaliES1 rna-NM_001178926.3_FaliES1 cds-NP_010952.3_FaliES1 99.0 100.0 Verified 1 1 1 True True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000192.1:15339-15776:+ gene-YER035W_JAY291 rna-NM_001178926.3_JAY291 cds-NP_010952.3_JAY291 100.0 100.0 Verified 1 1 1 True True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005411.1:221001-221438:+ gene-YER035W_MUCL30387 rna-NM_001178926.3_MUCL30387 cds-NP_010952.3_MUCL30387 99.0 100.0 Verified 1 1 1 True True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005443.1:217218-217655:+ gene-YER035W_MUCL30388 rna-NM_001178926.3_MUCL30388 cds-NP_010952.3_MUCL30388 98.8 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005283.1:215635-216072:+ gene-YER035W_MUCL39482 rna-NM_001178926.3_MUCL39482 cds-NP_010952.3_MUCL39482 99.0 100.0 Verified 1 1 1 True True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005427.1:222730-223167:+ gene-YER035W_MUCL42920 rna-NM_001178926.3_MUCL42920 cds-NP_010952.3_MUCL42920 99.5 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011814.1:222638-223075:+ gene-YER035W_NCIM3186 rna-NM_001178926.3_NCIM3186 cds-NP_010952.3_NCIM3186 98.6 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005267.1:220705-221142:+ gene-YER035W_NCYC1407 rna-NM_001178926.3_NCYC1407 cds-NP_010952.3_NCYC1407 99.0 100.0 Verified 1 1 1 True True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994144.1:231348-231785:+ gene-YER035W_PE2H3 rna-NM_001178926.3_PE2H3 cds-NP_010952.3_PE2H3 100.0 100.0 Verified 1 1 1 True True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999876.1:221289-221726:+ gene-YER035W_PE2H4 rna-NM_001178926.3_PE2H4 cds-NP_010952.3_PE2H4 100.0 100.0 Verified 1 1 1 True True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001137.3:222639-223076:+ gene-YER035W_S288C rna-NM_001178926.3_S288C cds-NP_010952.3_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000020.1:20605-21042:- gene-YER035W_SA1 rna-NM_001178926.3_SA1 cds-NP_010952.3_SA1 99.5 100.0 Verified 1 1 1 True True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005491.1:218333-218770:+ gene-YER035W_ThermosaccDry rna-NM_001178926.3_ThermosaccDry cds-NP_010952.3_ThermosaccDry 99.0 100.0 Verified 1 1 1 True True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005459.1:217444-217881:+ gene-YER035W_VR1 rna-NM_001178926.3_VR1 cds-NP_010952.3_VR1 100.0 100.0 Verified 1 1 1 True True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000009.1:215542-215979:+ gene-YER035W_ZTW1 rna-NM_001178926.3_ZTW1 cds-NP_010952.3_ZTW1 99.0 100.0 Verified 1 1 1 True True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047491.1:219404-219838:+ gene-YER035W_Sparadoxus rna-NM_001178926.3_Sparadoxus cds-NP_010952.3_Sparadoxus 85.6 99.3 Verified 1 1 1 False True False False False

Additional files