Gene name: ECM5
Reference locus (S288C): YMR176W
Gene biotype: protein_coding
Description: Protein ECM5; Subunit of the Snt2C complex; physically associates with Snt2p and Rpd3p; along with Snt2p, recruits Rpd3p to a small number of promoters; also colocalizes with Snt2p, independently of Rpd3p, to promoters of stress response genes in response to oxidative stress; contains ATP/GTP-binding site motif A; null mutant exhibits increased cellular volume, large drooping buds with elongated necks; relative distribution to the nucleus increases upon DNA replication stress
Top 10 interactors (score): RPD3 (0.987); BRE2 (0.984); SWD1 (0.981); SNT2 (0.956); RCO1 (0.931); RPH1 (0.925); JHD1 (0.924); GIS1 (0.917); ATP1 (0.907); ATP5 (0.907); ATP16 (0.907); ATP3 (0.907); ATP6 (0.896); RTT107 (0.881); SET1 (0.872); SET2 (0.867); EAF3 (0.863); SIN3 (0.855); SWR1 (0.846); ESA1 (0.826)
Homologues (species, bitscore): KDM5A (Homo sapiens, 116.7); Kdm5a (Mus musculus, 120.2); kdm5ba (Danio rerio, 114.0); kdm5b (Xenopus tropicalis, 106.7); lid (Drosophila melanogaster, 109.8); rbr-2 (Caenorhabditis elegans, 83.6); AT5G46910 (Arabidopsis thaliana, 77.4)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005307.1:651660-655895:+ | gene-YMR176W_AKU4011 | rna-NM_001182682.1_AKU4011 | cds-NP_013901.1_AKU4011 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000068.1:17218-21453:- | gene-YMR176W_BG1 | rna-NM_001182682.1_BG1 | cds-NP_013901.1_BG1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005515.1:595926-600161:+ | gene-YMR176W_Bruggeman | rna-NM_001182682.1_Bruggeman | cds-NP_013901.1_Bruggeman | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005531.1:598652-602887:+ | gene-YMR176W_CAT1 | rna-NM_001182682.1_CAT1 | cds-NP_013901.1_CAT1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005371.1:583944-588179:+ | gene-YMR176W_CBS1585 | rna-NM_001182682.1_CBS1585 | cds-NP_013901.1_CBS1585 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005355.1:588195-592430:+ | gene-YMR176W_CBS436 | rna-NM_001182682.1_CBS436 | cds-NP_013901.1_CBS436 | 99.9 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005339.1:696484-700719:+ | gene-YMR176W_CBS6412 | rna-NM_001182682.1_CBS6412 | cds-NP_013901.1_CBS6412 | 99.3 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005323.1:583086-587321:+ | gene-YMR176W_CBS6413 | rna-NM_001182682.1_CBS6413 | cds-NP_013901.1_CBS6413 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001534.1:606286-610521:+ | gene-YMR176W_CENPK1137D | rna-NM_001182682.1_CENPK1137D | cds-NP_013901.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005486.1:644321-648556:+ | gene-YMR176W_EthanolRed | rna-NM_001182682.1_EthanolRed | cds-NP_013901.1_EthanolRed | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005547.1:589258-593493:+ | gene-YMR176W_FaliES1 | rna-NM_001182682.1_FaliES1 | cds-NP_013901.1_FaliES1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000265.1:17037-21272:- | gene-YMR176W_JAY291 | rna-NM_001182682.1_JAY291 | cds-NP_013901.1_JAY291 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005419.1:589472-593707:+ | gene-YMR176W_MUCL30387 | rna-NM_001182682.1_MUCL30387 | cds-NP_013901.1_MUCL30387 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005451.1:596252-600487:+ | gene-YMR176W_MUCL30388 | rna-NM_001182682.1_MUCL30388 | cds-NP_013901.1_MUCL30388 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005291.1:584996-589231:+ | gene-YMR176W_MUCL39482 | rna-NM_001182682.1_MUCL39482 | cds-NP_013901.1_MUCL39482 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005435.1:592371-596606:+ | gene-YMR176W_MUCL42920 | rna-NM_001182682.1_MUCL42920 | cds-NP_013901.1_MUCL42920 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011822.1:611694-615929:+ | gene-YMR176W_NCIM3186 | rna-NM_001182682.1_NCIM3186 | cds-NP_013901.1_NCIM3186 | 99.2 | 100.0 | Unannotated | 1 | 1 | 0 | False | False | False | False | True |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005275.1:584631-588866:+ | gene-YMR176W_NCYC1407 | rna-NM_001182682.1_NCYC1407 | cds-NP_013901.1_NCYC1407 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994152.1:594529-598764:+ | gene-YMR176W_PE2H3 | rna-NM_001182682.1_PE2H3 | cds-NP_013901.1_PE2H3 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999884.1:595522-599757:+ | gene-YMR176W_PE2H4 | rna-NM_001182682.1_PE2H4 | cds-NP_013901.1_PE2H4 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001145.3:611740-615975:+ | gene-YMR176W_S288C | rna-NM_001182682.1_S288C | cds-NP_013901.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000002.1:192133-196368:- | gene-YMR176W_SA1 | rna-NM_001182682.1_SA1 | cds-NP_013901.1_SA1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005499.1:585915-590150:+ | gene-YMR176W_ThermosaccDry | rna-NM_001182682.1_ThermosaccDry | cds-NP_013901.1_ThermosaccDry | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005467.1:599087-603322:+ | gene-YMR176W_VR1 | rna-NM_001182682.1_VR1 | cds-NP_013901.1_VR1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000028.1:1705-5941:+ | gene-YMR176W_ZTW1 | rna-NM_001182682.1_ZTW1 | cds-NP_013901.1_ZTW1 | 99.8 | 100.0 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047499.1:603852-608108:+ | gene-YMR176W_Sparadoxus | rna-NM_001182682.1_Sparadoxus | cds-NP_013901.1_Sparadoxus | 85.1 | 99.8 | Verified | 1 | 1 | 1 | False | True | False | False | False |