Gene name: ECM22
Reference locus (S288C): YLR228C
Gene biotype: protein_coding
Description: Sterol regulatory element binding protein; regulates transcription of sterol biosynthetic genes upon sterol depletion, after relocating from intracellular membranes to perinuclear foci; redundant activator of filamentation with UPC2, up-regulating the expression of genes involved in filamentous growth; contains Zn[2]-Cys[6] binuclear cluster; ECM22 has a paralog, UPC2, that arose from the whole genome duplication
Top 10 interactors (score): MOT3 (0.924); ERG2 (0.871); ERG3 (0.794); UPC2 (0.79); ROX1 (0.751); ERG11 (0.697); RGM1 (0.692); STE12 (0.615); YDR246W-A (0.612); IXR1 (0.61); ERG5 (0.59); AUS1 (0.571); NHP6B (0.571); BOP2 (0.567); DAN1 (0.563); STB5 (0.558); MGA2 (0.557); SVF1 (0.553); ERG28 (0.549); PRR2 (0.546)
Homologues (species, bitscore): Unknown
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005306.1:554174-556621:- | gene-YLR228C_AKU4011 | rna-NM_001182115.1_AKU4011 | cds-NP_013329.1_AKU4011 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000082.1:8242-10686:- | gene-YLR228C_BG1 | rna-NM_001182115.1_BG1 | cds-NP_013329.1_BG1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005514.1:588464-590908:- | gene-YLR228C_Bruggeman | rna-NM_001182115.1_Bruggeman | cds-NP_013329.1_Bruggeman | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005530.1:587584-590028:- | gene-YLR228C_CAT1 | rna-NM_001182115.1_CAT1 | cds-NP_013329.1_CAT1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005370.1:589668-592115:- | gene-YLR228C_CBS1585 | rna-NM_001182115.1_CBS1585 | cds-NP_013329.1_CBS1585 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005354.1:573932-576376:- | gene-YLR228C_CBS436 | rna-NM_001182115.1_CBS436 | cds-NP_013329.1_CBS436 | 99.9 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005338.1:552643-555090:- | gene-YLR228C_CBS6412 | rna-NM_001182115.1_CBS6412 | cds-NP_013329.1_CBS6412 | 99.2 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005322.1:589963-592410:- | gene-YLR228C_CBS6413 | rna-NM_001182115.1_CBS6413 | cds-NP_013329.1_CBS6413 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001533.1:584630-587074:- | gene-YLR228C_CENPK1137D | rna-NM_001182115.1_CENPK1137D | cds-NP_013329.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005482.1:547754-550201:- | gene-YLR228C_EthanolRed | rna-NM_001182115.1_EthanolRed | cds-NP_013329.1_EthanolRed | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005546.1:576679-579126:- | gene-YLR228C_FaliES1 | rna-NM_001182115.1_FaliES1 | cds-NP_013329.1_FaliES1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000227.1:2995-5439:+ | gene-YLR228C_JAY291 | rna-NM_001182115.1_JAY291 | cds-NP_013329.1_JAY291 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005418.1:589325-591769:- | gene-YLR228C_MUCL30387 | rna-NM_001182115.1_MUCL30387 | cds-NP_013329.1_MUCL30387 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005450.1:593445-595889:- | gene-YLR228C_MUCL30388 | rna-NM_001182115.1_MUCL30388 | cds-NP_013329.1_MUCL30388 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005290.1:590649-593096:- | gene-YLR228C_MUCL39482 | rna-NM_001182115.1_MUCL39482 | cds-NP_013329.1_MUCL39482 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005434.1:585464-587908:- | gene-YLR228C_MUCL42920 | rna-NM_001182115.1_MUCL42920 | cds-NP_013329.1_MUCL42920 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011821.1:599993-602437:- | gene-YLR228C_NCIM3186 | rna-NM_001182115.1_NCIM3186 | cds-NP_013329.1_NCIM3186 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005274.1:577637-580084:- | gene-YLR228C_NCYC1407 | rna-NM_001182115.1_NCYC1407 | cds-NP_013329.1_NCYC1407 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994151.1:581407-583851:- | gene-YLR228C_PE2H3 | rna-NM_001182115.1_PE2H3 | cds-NP_013329.1_PE2H3 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999883.1:581151-583595:- | gene-YLR228C_PE2H4 | rna-NM_001182115.1_PE2H4 | cds-NP_013329.1_PE2H4 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001144.5:600019-602463:- | gene-YLR228C_S288C | rna-NM_001182115.1_S288C | cds-NP_013329.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000013.1:80010-82454:+ | gene-YLR228C_SA1 | rna-NM_001182115.1_SA1 | cds-NP_013329.1_SA1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005498.1:579179-581626:- | gene-YLR228C_ThermosaccDry | rna-NM_001182115.1_ThermosaccDry | cds-NP_013329.1_ThermosaccDry | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005466.1:590521-592965:- | gene-YLR228C_VR1 | rna-NM_001182115.1_VR1 | cds-NP_013329.1_VR1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000024.1:103467-105914:- | gene-YLR228C_ZTW1 | rna-NM_001182115.1_ZTW1 | cds-NP_013329.1_ZTW1 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047498.1:564639-567071:- | gene-YLR228C_Sparadoxus | rna-NM_001182115.1_Sparadoxus | cds-NP_013329.1_Sparadoxus | 89.3 | 99.3 | Verified | 1 | 1 | 1 | False | True | False | False | False |