ECM11 (YDR446W)


Gene profile

Gene name: ECM11
Reference locus (S288C): YDR446W
Gene biotype: protein_coding

Description: Meiosis-specific protein; component of the Synaptonemal Complex (SC) along with Gmc2p; required for efficient crossover formation and for the efficient loading of the SC transverse filament protein, Zip1p; is SUMOlytaed in a Gmc2p manner, and SUMOylation is required for its function in meiosis; GFP fusion protein is present in discrete clusters in the nucleus throughout mitosis; may be involved in maintaining chromatin structure

Top 10 interactors (score): GMC2 (0.975); ZIP1 (0.896); SPO22 (0.888); NFI1 (0.836); MSH4 (0.835); SPO16 (0.814); CST9 (0.812); SPO11 (0.787); ZIP2 (0.78); RED1 (0.76); NDT80 (0.717); YHR202W (0.713); YMR147W (0.691); PHO92 (0.683); YDR018C (0.678); SMT3 (0.677); YHR127W (0.618); DMC1 (0.613); HOP2 (0.597); ULP2 (0.574)

Homologues (species, bitscore): Unknown

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005298.1:1293629-1294537:+ gene-YDR446W_AKU4011 rna-NM_001180754.1_AKU4011 cds-NP_010734.1_AKU4011 99.4 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000039.1:171986-172894:+ gene-YDR446W_BG1 rna-NM_001180754.1_BG1 cds-NP_010734.1_BG1 100.0 100.0 Verified 1 1 1 True True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005506.1:1325088-1325996:+ gene-YDR446W_Bruggeman rna-NM_001180754.1_Bruggeman cds-NP_010734.1_Bruggeman 99.4 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005522.1:1302223-1303131:+ gene-YDR446W_CAT1 rna-NM_001180754.1_CAT1 cds-NP_010734.1_CAT1 100.0 100.0 Verified 1 1 1 True True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005362.1:1287936-1288844:+ gene-YDR446W_CBS1585 rna-NM_001180754.1_CBS1585 cds-NP_010734.1_CBS1585 99.4 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005346.1:1307305-1308213:+ gene-YDR446W_CBS436 rna-NM_001180754.1_CBS436 cds-NP_010734.1_CBS436 99.6 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005330.1:1283574-1284482:+ gene-YDR446W_CBS6412 rna-NM_001180754.1_CBS6412 cds-NP_010734.1_CBS6412 99.4 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005314.1:1306575-1307483:+ gene-YDR446W_CBS6413 rna-NM_001180754.1_CBS6413 cds-NP_010734.1_CBS6413 99.4 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001525.1:1352379-1353287:+ gene-YDR446W_CENPK1137D rna-NM_001180754.1_CENPK1137D cds-NP_010734.1_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005474.1:1296999-1297907:+ gene-YDR446W_EthanolRed rna-NM_001180754.1_EthanolRed cds-NP_010734.1_EthanolRed 99.5 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005538.1:1300550-1301458:+ gene-YDR446W_FaliES1 rna-NM_001180754.1_FaliES1 cds-NP_010734.1_FaliES1 99.5 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000263.1:44800-45708:+ gene-YDR446W_JAY291 rna-NM_001180754.1_JAY291 cds-NP_010734.1_JAY291 99.6 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005410.1:1307563-1308471:+ gene-YDR446W_MUCL30387 rna-NM_001180754.1_MUCL30387 cds-NP_010734.1_MUCL30387 99.5 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005442.1:1289587-1290495:+ gene-YDR446W_MUCL30388 rna-NM_001180754.1_MUCL30388 cds-NP_010734.1_MUCL30388 99.4 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005282.1:1279427-1280335:+ gene-YDR446W_MUCL39482 rna-NM_001180754.1_MUCL39482 cds-NP_010734.1_MUCL39482 99.4 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005426.1:1222225-1223133:+ gene-YDR446W_MUCL42920 rna-NM_001180754.1_MUCL42920 cds-NP_010734.1_MUCL42920 99.6 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011813.1:1353648-1354556:+ gene-YDR446W_NCIM3186 rna-NM_001180754.1_NCIM3186 cds-NP_010734.1_NCIM3186 99.0 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005266.1:1293192-1294100:+ gene-YDR446W_NCYC1407 rna-NM_001180754.1_NCYC1407 cds-NP_010734.1_NCYC1407 99.4 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994143.1:1304043-1304951:+ gene-YDR446W_PE2H3 rna-NM_001180754.1_PE2H3 cds-NP_010734.1_PE2H3 99.6 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999875.1:1309601-1310509:+ gene-YDR446W_PE2H4 rna-NM_001180754.1_PE2H4 cds-NP_010734.1_PE2H4 100.0 100.0 Verified 1 1 1 True True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001136.10:1353725-1354633:+ gene-YDR446W_S288C rna-NM_001180754.1_S288C cds-NP_010734.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000082.1:2928-3836:- gene-YDR446W_SA1 rna-NM_001180754.1_SA1 cds-NP_010734.1_SA1 100.0 100.0 Verified 1 1 1 True True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005490.1:1304774-1305682:+ gene-YDR446W_ThermosaccDry rna-NM_001180754.1_ThermosaccDry cds-NP_010734.1_ThermosaccDry 99.5 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005458.1:1320511-1321419:+ gene-YDR446W_VR1 rna-NM_001180754.1_VR1 cds-NP_010734.1_VR1 99.8 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000008.1:347430-348338:+ gene-YDR446W_ZTW1 rna-NM_001180754.1_ZTW1 cds-NP_010734.1_ZTW1 99.8 100.0 Verified 1 1 1 True True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047490.1:1307859-1308764:+ gene-YDR446W_Sparadoxus rna-NM_001180754.1_Sparadoxus cds-NP_010734.1_Sparadoxus 88.3 99.3 Verified 1 1 1 False True False False False

Additional files