Gene name: ECL1
Reference locus (S288C): YGR146C
Gene biotype: protein_coding
Description: Protein of unknown function; mitochondrial-dependent role in the extension of chronological lifespan; overexpression increases oxygen consumption and respiratory activity while deletion results in reduced oxygen consumption under conditions of caloric restriction; induced by iron homeostasis transcription factor Aft2p; multicopy suppressor of temperature sensitive hsf1 mutant; induced by treatment with 8-methoxypsoralen and UVA irradiation
Top 10 interactors (score): ICL1 (0.766); DCV1 (0.76); YFR012W-A (0.76); YGR146C-A (0.748); ARA2 (0.716); NAT2 (0.713); WHI3 (0.694); SBE22 (0.691); ICL2 (0.65); PDR5 (0.617); RFU1 (0.613); VHR2 (0.612); AKR2 (0.572); SLP1 (0.571); MSC2 (0.526); APE3 (0.489); CUL3 (0.455); IOC3 (0.451); MBF1 (0.45); TES1 (0.45)
Homologues (species, bitscore): Unknown
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005301.1:763922-764557:- | gene-YGR146C_AKU4011 | rna-NM_001181275.3_AKU4011 | cds-NP_011662.3_AKU4011 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000021.1:41842-42477:- | gene-YGR146C_BG1 | rna-NM_001181275.3_BG1 | cds-NP_011662.3_BG1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005509.1:769390-770025:- | gene-YGR146C_Bruggeman | rna-NM_001181275.3_Bruggeman | cds-NP_011662.3_Bruggeman | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005525.1:765349-765984:- | gene-YGR146C_CAT1 | rna-NM_001181275.3_CAT1 | cds-NP_011662.3_CAT1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005365.1:764656-765291:- | gene-YGR146C_CBS1585 | rna-NM_001181275.3_CBS1585 | cds-NP_011662.3_CBS1585 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005349.1:768309-768944:- | gene-YGR146C_CBS436 | rna-NM_001181275.3_CBS436 | cds-NP_011662.3_CBS436 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005333.1:755676-756311:- | gene-YGR146C_CBS6412 | rna-NM_001181275.3_CBS6412 | cds-NP_011662.3_CBS6412 | 99.6 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005317.1:761514-762149:- | gene-YGR146C_CBS6413 | rna-NM_001181275.3_CBS6413 | cds-NP_011662.3_CBS6413 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001528.1:783956-784591:- | gene-YGR146C_CENPK1137D | rna-NM_001181275.3_CENPK1137D | cds-NP_011662.3_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005477.1:750224-750859:- | gene-YGR146C_EthanolRed | rna-NM_001181275.3_EthanolRed | cds-NP_011662.3_EthanolRed | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005541.1:754312-754947:- | gene-YGR146C_FaliES1 | rna-NM_001181275.3_FaliES1 | cds-NP_011662.3_FaliES1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000224.1:2616-3251:+ | gene-YGR146C_JAY291 | rna-NM_001181275.3_JAY291 | cds-NP_011662.3_JAY291 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005413.1:767132-767767:- | gene-YGR146C_MUCL30387 | rna-NM_001181275.3_MUCL30387 | cds-NP_011662.3_MUCL30387 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005445.1:766824-767459:- | gene-YGR146C_MUCL30388 | rna-NM_001181275.3_MUCL30388 | cds-NP_011662.3_MUCL30388 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005285.1:760132-760767:- | gene-YGR146C_MUCL39482 | rna-NM_001181275.3_MUCL39482 | cds-NP_011662.3_MUCL39482 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005429.1:774562-775197:- | gene-YGR146C_MUCL42920 | rna-NM_001181275.3_MUCL42920 | cds-NP_011662.3_MUCL42920 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011816.1:784223-784858:- | gene-YGR146C_NCIM3186 | rna-NM_001181275.3_NCIM3186 | cds-NP_011662.3_NCIM3186 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005269.1:755332-755967:- | gene-YGR146C_NCYC1407 | rna-NM_001181275.3_NCYC1407 | cds-NP_011662.3_NCYC1407 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994146.1:774301-774936:- | gene-YGR146C_PE2H3 | rna-NM_001181275.3_PE2H3 | cds-NP_011662.3_PE2H3 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999878.1:779411-780046:- | gene-YGR146C_PE2H4 | rna-NM_001181275.3_PE2H4 | cds-NP_011662.3_PE2H4 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001139.9:784223-784858:- | gene-YGR146C_S288C | rna-NM_001181275.3_S288C | cds-NP_011662.3_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000035.1:19224-19859:- | gene-YGR146C_SA1 | rna-NM_001181275.3_SA1 | cds-NP_011662.3_SA1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005493.1:774935-775570:- | gene-YGR146C_ThermosaccDry | rna-NM_001181275.3_ThermosaccDry | cds-NP_011662.3_ThermosaccDry | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005461.1:879210-879845:- | gene-YGR146C_VR1 | rna-NM_001181275.3_VR1 | cds-NP_011662.3_VR1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000016.1:76783-77418:- | gene-YGR146C_ZTW1 | rna-NM_001181275.3_ZTW1 | cds-NP_011662.3_ZTW1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047493.1:764205-764840:- | gene-YGR146C_Sparadoxus | rna-NM_001181275.3_Sparadoxus | cds-NP_011662.3_Sparadoxus | 89.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |