EBP2 (YKL172W)


Gene profile

Gene name: EBP2
Reference locus (S288C): YKL172W
Gene biotype: protein_coding

Description: rRNA-processing protein EBP2; Required for 25S rRNA maturation and 60S ribosomal subunit assembly; localizes to the nucleolus and in foci along nuclear periphery; constituent of 66S pre-ribosomal particles; cooperates with Rrs1p and Mps3p to mediate telomere clustering by binding Sir4p, but is not involved in telomere tethering

Top 10 interactors (score): LOC1 (0.999); NMD3 (0.999); NUG1 (0.999); SSF1 (0.999); MAK16 (0.999); NOC2 (0.999); BRX1 (0.999); CBF5 (0.999); DBP9 (0.999); UTP11 (0.999); DBP3 (0.999); PUF6 (0.999); RRP14 (0.999); MAK21 (0.999); CIC1 (0.999); NOP4 (0.999); NOG1 (0.999); RLP7 (0.999); RRP15 (0.999); DBP10 (0.999)

Homologues (species, bitscore): EBNA1BP2 (Homo sapiens, 118.2); Ebna1bp2 (Mus musculus, 120.6); ebna1bp2 (Danio rerio, 115.5); ebna1bp2 (Xenopus tropicalis, 117.5); CG1542 (Drosophila melanogaster, 87.4); C18A3.3 (Caenorhabditis elegans, 94.0); AT3G22660 (Arabidopsis thaliana, 98.6)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005305.1:112614-113903:+ gene-YKL172W_AKU4011 rna-NM_001179738.1_AKU4011 cds-NP_012749.1_AKU4011 99.5 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000030.1:89172-90452:+ gene-YKL172W_BG1 rna-NM_001179738.1_BG1 cds-NP_012749.1_BG1 99.3 99.7 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005513.1:130004-131305:+ gene-YKL172W_Bruggeman rna-NM_001179738.1_Bruggeman cds-NP_012749.1_Bruggeman 98.3 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005529.1:124967-126247:+ gene-YKL172W_CAT1 rna-NM_001179738.1_CAT1 cds-NP_012749.1_CAT1 99.3 99.7 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005369.1:124598-125887:+ gene-YKL172W_CBS1585 rna-NM_001179738.1_CBS1585 cds-NP_012749.1_CBS1585 99.4 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005353.1:123363-124643:+ gene-YKL172W_CBS436 rna-NM_001179738.1_CBS436 cds-NP_012749.1_CBS436 99.4 99.7 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005337.1:110188-111477:+ gene-YKL172W_CBS6412 rna-NM_001179738.1_CBS6412 cds-NP_012749.1_CBS6412 99.5 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005321.1:125314-126603:+ gene-YKL172W_CBS6413 rna-NM_001179738.1_CBS6413 cds-NP_012749.1_CBS6413 99.5 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001532.1:125585-126868:+ gene-YKL172W_CENPK1137D rna-NM_001179738.1_CENPK1137D cds-NP_012749.1_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005481.1:123500-124807:+ gene-YKL172W_EthanolRed rna-NM_001179738.1_EthanolRed cds-NP_012749.1_EthanolRed 98.1 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005545.1:124201-125508:+ gene-YKL172W_FaliES1 rna-NM_001179738.1_FaliES1 cds-NP_012749.1_FaliES1 98.1 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000006.2:123185-124466:+ gene-YKL172W_JAY291 rna-NM_001179738.1_JAY291 cds-NP_012749.1_JAY291 99.3 99.7 Unannotated 1 1 0 False False False True False
MUCL30387 GCA_001738515.1 Bread Europe CM005417.1:132304-133593:+ gene-YKL172W_MUCL30387 rna-NM_001179738.1_MUCL30387 cds-NP_012749.1_MUCL30387 99.3 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005449.1:126648-127949:+ gene-YKL172W_MUCL30388 rna-NM_001179738.1_MUCL30388 cds-NP_012749.1_MUCL30388 98.3 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005289.1:124653-125942:+ gene-YKL172W_MUCL39482 rna-NM_001179738.1_MUCL39482 cds-NP_012749.1_MUCL39482 99.5 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005433.1:128988-130268:+ gene-YKL172W_MUCL42920 rna-NM_001179738.1_MUCL42920 cds-NP_012749.1_MUCL42920 99.6 99.7 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011820.1:125748-127031:+ gene-YKL172W_NCIM3186 rna-NM_001179738.1_NCIM3186 cds-NP_012749.1_NCIM3186 99.6 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005273.1:124677-125966:+ gene-YKL172W_NCYC1407 rna-NM_001179738.1_NCYC1407 cds-NP_012749.1_NCYC1407 99.4 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994150.1:131738-133018:+ gene-YKL172W_PE2H3 rna-NM_001179738.1_PE2H3 cds-NP_012749.1_PE2H3 99.3 99.7 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999882.1:128032-129312:+ gene-YKL172W_PE2H4 rna-NM_001179738.1_PE2H4 cds-NP_012749.1_PE2H4 99.3 99.7 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001143.9:125759-127042:+ gene-YKL172W_S288C rna-NM_001179738.1_S288C cds-NP_012749.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000008.1:41965-43242:+ gene-YKL172W_SA1 rna-NM_001179738.1_SA1 cds-NP_012749.1_SA1 99.2 99.5 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005497.1:124901-126208:+ gene-YKL172W_ThermosaccDry rna-NM_001179738.1_ThermosaccDry cds-NP_012749.1_ThermosaccDry 98.1 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005465.1:123443-124723:+ gene-YKL172W_VR1 rna-NM_001179738.1_VR1 cds-NP_012749.1_VR1 99.3 99.7 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000022.1:123312-124598:+ gene-YKL172W_ZTW1 rna-NM_001179738.1_ZTW1 cds-NP_012749.1_ZTW1 99.3 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047497.1:137842-139119:+ gene-YKL172W_Sparadoxus rna-NM_001179738.1_Sparadoxus cds-NP_012749.1_Sparadoxus 88.0 98.5 Verified 1 1 1 False True False False False

Additional files