Gene name: EAP1
Reference locus (S288C): YKL204W
Gene biotype: protein_coding
Description: eIF4E-associated protein, competes with eIF4G for binding to eIF4E; accelerates mRNA degradation by promoting decapping, facilitated by interaction with eIF4E; essential for Puf5p mediated repression; associates with Puf5p and Dhh1p; inhibits cap-dependent translation; functions independently of eIF4E to maintain genetic stability; plays a role in cell growth, implicated in the TOR signaling cascade
Top 10 interactors (score): CDC33 (0.999); CAF20 (0.974); SMY2 (0.958); SCP160 (0.944); YOR338W (0.901); DHH1 (0.892); TIF4631 (0.831); TIF1 (0.758); SBP1 (0.75); LSM1 (0.747); CBC2 (0.72); STO1 (0.72); BUD22 (0.697); HYP2 (0.695); TIF4632 (0.679); XRN1 (0.655); BFR1 (0.631); YPR158W-B (0.619); POM34 (0.617); TOP2 (0.608)
Homologues (species, bitscore): Unknown
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005305.1:40018-41916:+ | gene-YKL204W_AKU4011 | rna-NM_001179769.1_AKU4011 | cds-NP_012718.1_AKU4011 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000030.1:17102-19000:+ | gene-YKL204W_BG1 | rna-NM_001179769.1_BG1 | cds-NP_012718.1_BG1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005513.1:57690-59588:+ | gene-YKL204W_Bruggeman | rna-NM_001179769.1_Bruggeman | cds-NP_012718.1_Bruggeman | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005529.1:52882-54780:+ | gene-YKL204W_CAT1 | rna-NM_001179769.1_CAT1 | cds-NP_012718.1_CAT1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005369.1:52030-53928:+ | gene-YKL204W_CBS1585 | rna-NM_001179769.1_CBS1585 | cds-NP_012718.1_CBS1585 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005353.1:51231-53129:+ | gene-YKL204W_CBS436 | rna-NM_001179769.1_CBS436 | cds-NP_012718.1_CBS436 | 99.6 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005337.1:37287-39185:+ | gene-YKL204W_CBS6412 | rna-NM_001179769.1_CBS6412 | cds-NP_012718.1_CBS6412 | 99.9 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005321.1:52667-54565:+ | gene-YKL204W_CBS6413 | rna-NM_001179769.1_CBS6413 | cds-NP_012718.1_CBS6413 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001532.1:53486-55384:+ | gene-YKL204W_CENPK1137D | rna-NM_001179769.1_CENPK1137D | cds-NP_012718.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005481.1:51501-53399:+ | gene-YKL204W_EthanolRed | rna-NM_001179769.1_EthanolRed | cds-NP_012718.1_EthanolRed | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005545.1:51560-53458:+ | gene-YKL204W_FaliES1 | rna-NM_001179769.1_FaliES1 | cds-NP_012718.1_FaliES1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000006.2:51174-53072:+ | gene-YKL204W_JAY291 | rna-NM_001179769.1_JAY291 | cds-NP_012718.1_JAY291 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005417.1:60225-62123:+ | gene-YKL204W_MUCL30387 | rna-NM_001179769.1_MUCL30387 | cds-NP_012718.1_MUCL30387 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005449.1:54313-56211:+ | gene-YKL204W_MUCL30388 | rna-NM_001179769.1_MUCL30388 | cds-NP_012718.1_MUCL30388 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005289.1:52087-53985:+ | gene-YKL204W_MUCL39482 | rna-NM_001179769.1_MUCL39482 | cds-NP_012718.1_MUCL39482 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005433.1:55381-57279:+ | gene-YKL204W_MUCL42920 | rna-NM_001179769.1_MUCL42920 | cds-NP_012718.1_MUCL42920 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011820.1:53693-55591:+ | gene-YKL204W_NCIM3186 | rna-NM_001179769.1_NCIM3186 | cds-NP_012718.1_NCIM3186 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005273.1:52111-54009:+ | gene-YKL204W_NCYC1407 | rna-NM_001179769.1_NCYC1407 | cds-NP_012718.1_NCYC1407 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994150.1:59809-61707:+ | gene-YKL204W_PE2H3 | rna-NM_001179769.1_PE2H3 | cds-NP_012718.1_PE2H3 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999882.1:56007-57905:+ | gene-YKL204W_PE2H4 | rna-NM_001179769.1_PE2H4 | cds-NP_012718.1_PE2H4 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001143.9:53704-55602:+ | gene-YKL204W_S288C | rna-NM_001179769.1_S288C | cds-NP_012718.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000092.1:12271-14169:- | gene-YKL204W_SA1 | rna-NM_001179769.1_SA1 | cds-NP_012718.1_SA1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005497.1:52308-54206:+ | gene-YKL204W_ThermosaccDry | rna-NM_001179769.1_ThermosaccDry | cds-NP_012718.1_ThermosaccDry | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005465.1:51413-53311:+ | gene-YKL204W_VR1 | rna-NM_001179769.1_VR1 | cds-NP_012718.1_VR1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000022.1:51221-53119:+ | gene-YKL204W_ZTW1 | rna-NM_001179769.1_ZTW1 | cds-NP_012718.1_ZTW1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047497.1:59968-61863:+ | gene-YKL204W_Sparadoxus | rna-NM_001179769.1_Sparadoxus | cds-NP_012718.1_Sparadoxus | 89.8 | 99.8 | Verified | 1 | 1 | 0 | False | False | False | True | False |