EAF1 (YDR359C)


Gene profile

Gene name: EAF1
Reference locus (S288C): YDR359C
Gene biotype: protein_coding

Description: Chromatin modification-related protein EAF1; Component of the NuA4 histone acetyltransferase complex; acts as a platform for assembly of NuA4 subunits into the native complex; required for initiation of pre-meiotic DNA replication, likely due to its requirement for expression of IME1; Belongs to the EAF1 family

Top 10 interactors (score): EAF5 (0.999); TRA1 (0.998); ARP4 (0.998); ESA1 (0.998); EAF3 (0.997); SWC4 (0.996); EPL1 (0.996); YAF9 (0.996); ACT1 (0.995); YNG2 (0.993); EAF7 (0.984); EAF6 (0.981); GCN5 (0.977); HFI1 (0.932); ADA2 (0.926); SAS2 (0.918); NGG1 (0.915); SAS5 (0.909); SAS4 (0.905); AHC1 (0.9)

Homologues (species, bitscore): ep400 (Xenopus tropicalis, 50.8); ssl-1 (Caenorhabditis elegans, 52.4)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005298.1:1137998-1140946:- gene-YDR359C_AKU4011 rna-NM_001180667.3_AKU4011 cds-NP_010646.4_AKU4011 99.5 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000039.1:16549-19497:- gene-YDR359C_BG1 rna-NM_001180667.3_BG1 cds-NP_010646.4_BG1 99.8 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005506.1:1168653-1171601:- gene-YDR359C_Bruggeman rna-NM_001180667.3_Bruggeman cds-NP_010646.4_Bruggeman 99.6 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005522.1:1147243-1150191:- gene-YDR359C_CAT1 rna-NM_001180667.3_CAT1 cds-NP_010646.4_CAT1 99.8 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005362.1:1132715-1135663:- gene-YDR359C_CBS1585 rna-NM_001180667.3_CBS1585 cds-NP_010646.4_CBS1585 99.5 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005346.1:1151299-1154247:- gene-YDR359C_CBS436 rna-NM_001180667.3_CBS436 cds-NP_010646.4_CBS436 99.9 100.0 Mismatch 1 1 1 True True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005330.1:1128975-1131923:- gene-YDR359C_CBS6412 rna-NM_001180667.3_CBS6412 cds-NP_010646.4_CBS6412 99.5 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005314.1:1150865-1153813:- gene-YDR359C_CBS6413 rna-NM_001180667.3_CBS6413 cds-NP_010646.4_CBS6413 99.5 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001525.1:1190581-1193529:- gene-YDR359C_CENPK1137D rna-NM_001180667.3_CENPK1137D cds-NP_010646.4_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005474.1:1142400-1145348:- gene-YDR359C_EthanolRed rna-NM_001180667.3_EthanolRed cds-NP_010646.4_EthanolRed 99.4 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005538.1:1145683-1148631:- gene-YDR359C_FaliES1 rna-NM_001180667.3_FaliES1 cds-NP_010646.4_FaliES1 99.4 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000057.1:42439-45387:+ gene-YDR359C_JAY291 rna-NM_001180667.3_JAY291 cds-NP_010646.4_JAY291 99.8 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005410.1:1151951-1154899:- gene-YDR359C_MUCL30387 rna-NM_001180667.3_MUCL30387 cds-NP_010646.4_MUCL30387 99.9 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005442.1:1134555-1137503:- gene-YDR359C_MUCL30388 rna-NM_001180667.3_MUCL30388 cds-NP_010646.4_MUCL30388 99.4 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005282.1:1124249-1127197:- gene-YDR359C_MUCL39482 rna-NM_001180667.3_MUCL39482 cds-NP_010646.4_MUCL39482 99.5 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005426.1:1066185-1069133:- gene-YDR359C_MUCL42920 rna-NM_001180667.3_MUCL42920 cds-NP_010646.4_MUCL42920 99.9 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011813.1:1191859-1194807:- gene-YDR359C_NCIM3186 rna-NM_001180667.3_NCIM3186 cds-NP_010646.4_NCIM3186 99.2 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005266.1:1137921-1140869:- gene-YDR359C_NCYC1407 rna-NM_001180667.3_NCYC1407 cds-NP_010646.4_NCYC1407 99.5 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994143.1:1148352-1151300:- gene-YDR359C_PE2H3 rna-NM_001180667.3_PE2H3 cds-NP_010646.4_PE2H3 99.8 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999875.1:1153937-1156885:- gene-YDR359C_PE2H4 rna-NM_001180667.3_PE2H4 cds-NP_010646.4_PE2H4 99.8 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001136.10:1191936-1194884:- gene-YDR359C_S288C rna-NM_001180667.3_S288C cds-NP_010646.4_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000072.1:16630-19578:- gene-YDR359C_SA1 rna-NM_001180667.3_SA1 cds-NP_010646.4_SA1 99.8 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005490.1:1149964-1152912:- gene-YDR359C_ThermosaccDry rna-NM_001180667.3_ThermosaccDry cds-NP_010646.4_ThermosaccDry 99.4 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005469.1:577316-580264:- gene-YDR359C_VR1 rna-NM_001180667.3_VR1 cds-NP_010646.4_VR1 99.8 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000008.1:192798-195746:- gene-YDR359C_ZTW1 rna-NM_001180667.3_ZTW1 cds-NP_010646.4_ZTW1 99.4 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047490.1:1143873-1146821:- gene-YDR359C_Sparadoxus rna-NM_001180667.3_Sparadoxus cds-NP_010646.4_Sparadoxus 86.6 99.6 Verified 1 1 1 False True False False False

Additional files