Gene name: DYS1
Reference locus (S288C): YHR068W
Gene biotype: protein_coding
Description: Deoxyhypusine synthase; catalyzes formation of deoxyhypusine, the first step in hypusine biosynthesis; triggers posttranslational hypusination of translation elongation factor eIF-5A and regulates its intracellular levels; tetrameric; human homolog DHPS allows growth of yeast haploid dys1 null mutant after sporulation of heterozygous diploid
Top 10 interactors (score): LIA1 (0.999); ANB1 (0.999); HYP2 (0.999); SPE1 (0.899); FUN12 (0.831); NOP58 (0.754); THS1 (0.743); WRS1 (0.735); SSZ1 (0.732); SPE3 (0.731); GUA1 (0.73); MES1 (0.716); SPE2 (0.706); FRS2 (0.693); SPE4 (0.688); APL2 (0.687); KRS1 (0.667); YTM1 (0.659); SRP1 (0.656); RRS1 (0.65)
Homologues (species, bitscore): DHPS (Homo sapiens, 424.5); Dhps (Mus musculus, 427.2); dhps (Danio rerio, 431.0); dhps (Xenopus tropicalis, 413.7); CG8005 (Drosophila melanogaster, 407.5); dhps-1 (Caenorhabditis elegans, 407.9); DHS (Arabidopsis thaliana, 408.3)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005302.1:218412-219575:+ | gene-YHR068W_AKU4011 | rna-NM_001179198.1_AKU4011 | cds-NP_011935.1_AKU4011 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000053.1:139843-141006:+ | gene-YHR068W_BG1 | rna-NM_001179198.1_BG1 | cds-NP_011935.1_BG1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005510.1:226152-227315:+ | gene-YHR068W_Bruggeman | rna-NM_001179198.1_Bruggeman | cds-NP_011935.1_Bruggeman | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005526.1:220954-222117:+ | gene-YHR068W_CAT1 | rna-NM_001179198.1_CAT1 | cds-NP_011935.1_CAT1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005366.1:217521-218684:+ | gene-YHR068W_CBS1585 | rna-NM_001179198.1_CBS1585 | cds-NP_011935.1_CBS1585 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005350.1:215459-216622:+ | gene-YHR068W_CBS436 | rna-NM_001179198.1_CBS436 | cds-NP_011935.1_CBS436 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005328.1:217733-218896:+ | gene-YHR068W_CBS6412 | rna-NM_001179198.1_CBS6412 | cds-NP_011935.1_CBS6412 | 99.4 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005318.1:218564-219727:+ | gene-YHR068W_CBS6413 | rna-NM_001179198.1_CBS6413 | cds-NP_011935.1_CBS6413 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001529.1:225297-226460:+ | gene-YHR068W_CENPK1137D | rna-NM_001179198.1_CENPK1137D | cds-NP_011935.1_CENPK1137D | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005478.1:278079-279242:+ | gene-YHR068W_EthanolRed | rna-NM_001179198.1_EthanolRed | cds-NP_011935.1_EthanolRed | 99.4 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005542.1:218875-220038:+ | gene-YHR068W_FaliES1 | rna-NM_001179198.1_FaliES1 | cds-NP_011935.1_FaliES1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000394.1:1623-2786:+ | gene-YHR068W_JAY291 | rna-NM_001179198.1_JAY291 | cds-NP_011935.1_JAY291 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005414.1:225890-227053:+ | gene-YHR068W_MUCL30387 | rna-NM_001179198.1_MUCL30387 | cds-NP_011935.1_MUCL30387 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005446.1:225785-226948:+ | gene-YHR068W_MUCL30388 | rna-NM_001179198.1_MUCL30388 | cds-NP_011935.1_MUCL30388 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005286.1:217787-218950:+ | gene-YHR068W_MUCL39482 | rna-NM_001179198.1_MUCL39482 | cds-NP_011935.1_MUCL39482 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005430.1:224665-225828:+ | gene-YHR068W_MUCL42920 | rna-NM_001179198.1_MUCL42920 | cds-NP_011935.1_MUCL42920 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011817.1:232015-233178:+ | gene-YHR068W_NCIM3186 | rna-NM_001179198.1_NCIM3186 | cds-NP_011935.1_NCIM3186 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005274.1:689428-690591:+ | gene-YHR068W_NCYC1407 | rna-NM_001179198.1_NCYC1407 | cds-NP_011935.1_NCYC1407 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994147.1:219988-221151:+ | gene-YHR068W_PE2H3 | rna-NM_001179198.1_PE2H3 | cds-NP_011935.1_PE2H3 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999879.1:227435-228598:+ | gene-YHR068W_PE2H4 | rna-NM_001179198.1_PE2H4 | cds-NP_011935.1_PE2H4 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001140.6:232133-233296:+ | gene-YHR068W_S288C | rna-NM_001179198.1_S288C | cds-NP_011935.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000014.1:126124-127287:- | gene-YHR068W_SA1 | rna-NM_001179198.1_SA1 | cds-NP_011935.1_SA1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005494.1:219977-221140:+ | gene-YHR068W_ThermosaccDry | rna-NM_001179198.1_ThermosaccDry | cds-NP_011935.1_ThermosaccDry | 99.4 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005462.1:227597-228760:+ | gene-YHR068W_VR1 | rna-NM_001179198.1_VR1 | cds-NP_011935.1_VR1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000017.1:211529-212692:+ | gene-YHR068W_ZTW1 | rna-NM_001179198.1_ZTW1 | cds-NP_011935.1_ZTW1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047494.1:217092-218255:+ | gene-YHR068W_Sparadoxus | rna-NM_001179198.1_Sparadoxus | cds-NP_011935.1_Sparadoxus | 94.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |