Gene name: DYN2
Reference locus (S288C): YDR424C
Gene biotype: protein_coding
Description: Cytoplasmic light chain dynein, microtubule motor protein; required for intracellular transport and cell division; involved in mitotic spindle positioning; forms complex with dynein intermediate chain Pac11p that promotes Dyn1p homodimerization, potentiates motor processivity; Dyn2p-Pac11p complex important for interaction of dynein motor complex with dynactin complex; acts as molecular glue to dimerize, stabilize Nup82-Nsp1-Nup159 complex module of cytoplasmic pore filaments
Top 10 interactors (score): DYN1 (0.999); PAC1 (0.997); PAC11 (0.997); NUP159 (0.994); PEX14 (0.98); DYN3 (0.961); PEX17 (0.935); PEX13 (0.928); PEX11 (0.925); PEX8 (0.91); PEX5 (0.909); PEX10 (0.904); PEX12 (0.9); PEX19 (0.9); PEX2 (0.9); NIP100 (0.824); VPS30 (0.801); GLE2 (0.801); NUP42 (0.77); RAD9 (0.737)
Homologues (species, bitscore): DYNLL1 (Homo sapiens, 103.6); Dynll1 (Mus musculus, 103.6); dynll1 (Danio rerio, 104.4); dynll2 (Xenopus tropicalis, 102.4); ctp (Drosophila melanogaster, 104.0); dlc-1 (Caenorhabditis elegans, 104.0); AT4G15930 (Arabidopsis thaliana, 98.6)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005298.1:1259653-1260107:- | gene-YDR424C_AKU4011 | rna-NM_001180732.1_AKU4011 | cds-NP_010712.1_AKU4011 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000039.1:137994-138448:- | gene-YDR424C_BG1 | rna-NM_001180732.1_BG1 | cds-NP_010712.1_BG1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005506.1:1290044-1290498:- | gene-YDR424C_Bruggeman | rna-NM_001180732.1_Bruggeman | cds-NP_010712.1_Bruggeman | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005522.1:1268238-1268692:- | gene-YDR424C_CAT1 | rna-NM_001180732.1_CAT1 | cds-NP_010712.1_CAT1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005362.1:1253982-1254436:- | gene-YDR424C_CBS1585 | rna-NM_001180732.1_CBS1585 | cds-NP_010712.1_CBS1585 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005346.1:1273318-1273772:- | gene-YDR424C_CBS436 | rna-NM_001180732.1_CBS436 | cds-NP_010712.1_CBS436 | 99.6 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005330.1:1249948-1250402:- | gene-YDR424C_CBS6412 | rna-NM_001180732.1_CBS6412 | cds-NP_010712.1_CBS6412 | 99.6 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005314.1:1272097-1272551:- | gene-YDR424C_CBS6413 | rna-NM_001180732.1_CBS6413 | cds-NP_010712.1_CBS6413 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001525.1:1318055-1318509:- | gene-YDR424C_CENPK1137D | rna-NM_001180732.1_CENPK1137D | cds-NP_010712.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005474.1:1263236-1263690:- | gene-YDR424C_EthanolRed | rna-NM_001180732.1_EthanolRed | cds-NP_010712.1_EthanolRed | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005538.1:1266543-1266997:- | gene-YDR424C_FaliES1 | rna-NM_001180732.1_FaliES1 | cds-NP_010712.1_FaliES1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000263.1:10820-11274:- | gene-YDR424C_JAY291 | rna-NM_001180732.1_JAY291 | cds-NP_010712.1_JAY291 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005410.1:1273686-1274140:- | gene-YDR424C_MUCL30387 | rna-NM_001180732.1_MUCL30387 | cds-NP_010712.1_MUCL30387 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005442.1:1255622-1256076:- | gene-YDR424C_MUCL30388 | rna-NM_001180732.1_MUCL30388 | cds-NP_010712.1_MUCL30388 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005282.1:1245474-1245928:- | gene-YDR424C_MUCL39482 | rna-NM_001180732.1_MUCL39482 | cds-NP_010712.1_MUCL39482 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005426.1:1187878-1188332:- | gene-YDR424C_MUCL42920 | rna-NM_001180732.1_MUCL42920 | cds-NP_010712.1_MUCL42920 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011813.1:1319310-1319764:- | gene-YDR424C_NCIM3186 | rna-NM_001180732.1_NCIM3186 | cds-NP_010712.1_NCIM3186 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005266.1:1259238-1259692:- | gene-YDR424C_NCYC1407 | rna-NM_001180732.1_NCYC1407 | cds-NP_010712.1_NCYC1407 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994143.1:1270063-1270517:- | gene-YDR424C_PE2H3 | rna-NM_001180732.1_PE2H3 | cds-NP_010712.1_PE2H3 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999875.1:1275631-1276085:- | gene-YDR424C_PE2H4 | rna-NM_001180732.1_PE2H4 | cds-NP_010712.1_PE2H4 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001136.10:1319387-1319841:- | gene-YDR424C_S288C | rna-NM_001180732.1_S288C | cds-NP_010712.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000082.1:37380-37834:+ | gene-YDR424C_SA1 | rna-NM_001180732.1_SA1 | cds-NP_010712.1_SA1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005490.1:1270805-1271259:- | gene-YDR424C_ThermosaccDry | rna-NM_001180732.1_ThermosaccDry | cds-NP_010712.1_ThermosaccDry | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005458.1:1286025-1286479:- | gene-YDR424C_VR1 | rna-NM_001180732.1_VR1 | cds-NP_010712.1_VR1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000008.1:313449-313903:- | gene-YDR424C_ZTW1 | rna-NM_001180732.1_ZTW1 | cds-NP_010712.1_ZTW1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047490.1:1267160-1267648:- | gene-YDR424C_Sparadoxus | rna-NM_001180732.1_Sparadoxus | cds-NP_010712.1_Sparadoxus | 93.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |