Gene name: DUT1
Reference locus (S288C): YBR252W
Gene biotype: protein_coding
Description: Deoxyuridine 5'-triphosphate nucleotidohydrolase; Deoxyuridine triphosphate diphosphatase (dUTPase); catalyzes hydrolysis of dUTP to dUMP and PPi, thereby preventing incorporation of uracil into DNA during replication; critical for the maintenance of genetic stability; also has diphosphatase activity on deoxyinosine triphosphate; human homolog DUT allows growth of yeast haploid dut1 null mutant after sporulation of heterozygous diploid
Top 10 interactors (score): CDC21 (0.999); CDC8 (0.997); UNG1 (0.996); DCD1 (0.995); POL1 (0.977); HAM1 (0.966); PRI1 (0.965); APN2 (0.963); RNR3 (0.963); POL30 (0.959); YNK1 (0.957); MCM6 (0.956); RNR1 (0.954); MCM4 (0.952); APN1 (0.951); RFC4 (0.95); MCM5 (0.949); POL12 (0.946); RFC5 (0.946); RNH201 (0.944)
Homologues (species, bitscore): DUT (Homo sapiens, 154.8); Dut (Mus musculus, 149.4); dut (Danio rerio, 148.7); dUTPase (Drosophila melanogaster, 155.2); dut-1 (Caenorhabditis elegans, 155.2); DUT1 (Arabidopsis thaliana, 157.9)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005296.1:706900-707343:+ | gene-YBR252W_AKU4011 | rna-NM_001178600.3_AKU4011 | cds-NP_009811.3_AKU4011 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000066.1:77918-78361:+ | gene-YBR252W_BG1 | rna-NM_001178600.3_BG1 | cds-NP_009811.3_BG1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005504.1:708062-708505:+ | gene-YBR252W_Bruggeman | rna-NM_001178600.3_Bruggeman | cds-NP_009811.3_Bruggeman | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005520.1:711816-712259:+ | gene-YBR252W_CAT1 | rna-NM_001178600.3_CAT1 | cds-NP_009811.3_CAT1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005360.1:698466-698909:+ | gene-YBR252W_CBS1585 | rna-NM_001178600.3_CBS1585 | cds-NP_009811.3_CBS1585 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005344.1:704907-705350:+ | gene-YBR252W_CBS436 | rna-NM_001178600.3_CBS436 | cds-NP_009811.3_CBS436 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005328.1:793081-793524:+ | gene-YBR252W_CBS6412 | rna-NM_001178600.3_CBS6412 | cds-NP_009811.3_CBS6412 | 99.5 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005312.1:704514-704957:+ | gene-YBR252W_CBS6413 | rna-NM_001178600.3_CBS6413 | cds-NP_009811.3_CBS6413 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001523.1:716518-716961:+ | gene-YBR252W_CENPK1137D | rna-NM_001178600.3_CENPK1137D | cds-NP_009811.3_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005472.1:829932-830375:+ | gene-YBR252W_EthanolRed | rna-NM_001178600.3_EthanolRed | cds-NP_009811.3_EthanolRed | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005536.1:723279-723722:+ | gene-YBR252W_FaliES1 | rna-NM_001178600.3_FaliES1 | cds-NP_009811.3_FaliES1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000067.1:80330-80773:- | gene-YBR252W_JAY291 | rna-NM_001178600.3_JAY291 | cds-NP_009811.3_JAY291 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005408.1:710105-710548:+ | gene-YBR252W_MUCL30387 | rna-NM_001178600.3_MUCL30387 | cds-NP_009811.3_MUCL30387 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005440.1:727188-727631:+ | gene-YBR252W_MUCL30388 | rna-NM_001178600.3_MUCL30388 | cds-NP_009811.3_MUCL30388 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005280.1:696773-697216:+ | gene-YBR252W_MUCL39482 | rna-NM_001178600.3_MUCL39482 | cds-NP_009811.3_MUCL39482 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005424.1:706641-707084:+ | gene-YBR252W_MUCL42920 | rna-NM_001178600.3_MUCL42920 | cds-NP_009811.3_MUCL42920 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011811.1:722408-722851:+ | gene-YBR252W_NCIM3186 | rna-NM_001178600.3_NCIM3186 | cds-NP_009811.3_NCIM3186 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005264.1:698662-699105:+ | gene-YBR252W_NCYC1407 | rna-NM_001178600.3_NCYC1407 | cds-NP_009811.3_NCYC1407 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994141.1:721791-722234:+ | gene-YBR252W_PE2H3 | rna-NM_001178600.3_PE2H3 | cds-NP_009811.3_PE2H3 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999873.1:719467-719910:+ | gene-YBR252W_PE2H4 | rna-NM_001178600.3_PE2H4 | cds-NP_009811.3_PE2H4 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001134.8:722611-723054:+ | gene-YBR252W_S288C | rna-NM_001178600.3_S288C | cds-NP_009811.3_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000019.1:77739-78182:+ | gene-YBR252W_SA1 | rna-NM_001178600.3_SA1 | cds-NP_009811.3_SA1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005488.1:722271-722714:+ | gene-YBR252W_ThermosaccDry | rna-NM_001178600.3_ThermosaccDry | cds-NP_009811.3_ThermosaccDry | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005456.1:702488-702931:+ | gene-YBR252W_VR1 | rna-NM_001178600.3_VR1 | cds-NP_009811.3_VR1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000003.1:695120-695563:+ | gene-YBR252W_ZTW1 | rna-NM_001178600.3_ZTW1 | cds-NP_009811.3_ZTW1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047488.1:739031-739474:+ | gene-YBR252W_Sparadoxus | rna-NM_001178600.3_Sparadoxus | cds-NP_009811.3_Sparadoxus | 89.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |