DUS4 (YLR405W)


Gene profile

Gene name: DUS4
Reference locus (S288C): YLR405W
Gene biotype: protein_coding

Description: tRNA-dihydrouridine(20a/20b) synthase [NAD(P)+]; Dihydrouridine synthase; member of a widespread family of conserved proteins including Smm1p, Dus1p, and Dus3p; Belongs to the Dus family. Dus4 subfamily

Top 10 interactors (score): TRM10 (0.94); TRM1 (0.893); GCD14 (0.891); TRM5 (0.876); NCL1 (0.861); YET3 (0.853); TRM7 (0.83); GCD10 (0.809); DEG1 (0.802); TRM11 (0.795); TRM8 (0.709); RFS1 (0.692); TRM112 (0.676); DRE2 (0.673); LOT6 (0.622); TRM732 (0.617); ATG4 (0.605); PUS1 (0.604); DUS1 (0.591); TAD3 (0.579)

Homologues (species, bitscore): DUS4L (Homo sapiens, 230.7); Dus4l (Mus musculus, 233.4); dus4l (Danio rerio, 228.4); dus4l (Xenopus tropicalis, 225.7); CG10495 (Drosophila melanogaster, 176.0); C45G9.2 (Caenorhabditis elegans, 189.9); AT5G67220 (Arabidopsis thaliana, 161.4)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005306.1:879324-880427:+ gene-YLR405W_AKU4011 rna-NM_001182293.1_AKU4011 cds-NP_013509.1_AKU4011 98.8 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000048.1:111467-112570:+ gene-YLR405W_BG1 rna-NM_001182293.1_BG1 cds-NP_013509.1_BG1 99.9 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005514.1:917629-918732:+ gene-YLR405W_Bruggeman rna-NM_001182293.1_Bruggeman cds-NP_013509.1_Bruggeman 98.8 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005530.1:913153-914256:+ gene-YLR405W_CAT1 rna-NM_001182293.1_CAT1 cds-NP_013509.1_CAT1 99.9 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005370.1:914919-916022:+ gene-YLR405W_CBS1585 rna-NM_001182293.1_CBS1585 cds-NP_013509.1_CBS1585 98.7 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005354.1:898558-899661:+ gene-YLR405W_CBS436 rna-NM_001182293.1_CBS436 cds-NP_013509.1_CBS436 99.9 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005338.1:950961-952064:+ gene-YLR405W_CBS6412 rna-NM_001182293.1_CBS6412 cds-NP_013509.1_CBS6412 98.8 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005322.1:915211-916314:+ gene-YLR405W_CBS6413 rna-NM_001182293.1_CBS6413 cds-NP_013509.1_CBS6413 98.8 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001533.1:914600-915703:+ gene-YLR405W_CENPK1137D rna-NM_001182293.1_CENPK1137D cds-NP_013509.1_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005482.1:871866-872969:+ gene-YLR405W_EthanolRed rna-NM_001182293.1_EthanolRed cds-NP_013509.1_EthanolRed 98.8 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005546.1:901176-902279:+ gene-YLR405W_FaliES1 rna-NM_001182293.1_FaliES1 cds-NP_013509.1_FaliES1 98.8 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000434.1:54336-55439:+ gene-YLR405W_JAY291 rna-NM_001182293.1_JAY291 cds-NP_013509.1_JAY291 99.3 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005418.1:916495-917598:+ gene-YLR405W_MUCL30387 rna-NM_001182293.1_MUCL30387 cds-NP_013509.1_MUCL30387 98.8 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005450.1:922593-923696:+ gene-YLR405W_MUCL30388 rna-NM_001182293.1_MUCL30388 cds-NP_013509.1_MUCL30388 98.8 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005290.1:916139-917242:+ gene-YLR405W_MUCL39482 rna-NM_001182293.1_MUCL39482 cds-NP_013509.1_MUCL39482 98.7 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005434.1:910795-911898:+ gene-YLR405W_MUCL42920 rna-NM_001182293.1_MUCL42920 cds-NP_013509.1_MUCL42920 98.8 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011821.1:929763-930866:+ gene-YLR405W_NCIM3186 rna-NM_001182293.1_NCIM3186 cds-NP_013509.1_NCIM3186 98.8 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005274.1:925320-926423:+ gene-YLR405W_NCYC1407 rna-NM_001182293.1_NCYC1407 cds-NP_013509.1_NCYC1407 98.8 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994151.1:911717-912820:+ gene-YLR405W_PE2H3 rna-NM_001182293.1_PE2H3 cds-NP_013509.1_PE2H3 99.3 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999883.1:911461-912564:+ gene-YLR405W_PE2H4 rna-NM_001182293.1_PE2H4 cds-NP_013509.1_PE2H4 99.3 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001144.5:929789-930892:+ gene-YLR405W_S288C rna-NM_001182293.1_S288C cds-NP_013509.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000007.1:117796-118899:- gene-YLR405W_SA1 rna-NM_001182293.1_SA1 cds-NP_013509.1_SA1 99.3 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005498.1:904255-905358:+ gene-YLR405W_ThermosaccDry rna-NM_001182293.1_ThermosaccDry cds-NP_013509.1_ThermosaccDry 98.8 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005466.1:916807-917910:+ gene-YLR405W_VR1 rna-NM_001182293.1_VR1 cds-NP_013509.1_VR1 99.3 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000025.1:240973-242076:+ gene-YLR405W_ZTW1 rna-NM_001182293.1_ZTW1 cds-NP_013509.1_ZTW1 98.8 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047498.1:889818-890921:+ gene-YLR405W_Sparadoxus rna-NM_001182293.1_Sparadoxus cds-NP_013509.1_Sparadoxus 89.5 100.0 Unannotated 1 1 0 False False False False True

Additional files