Gene name: DUS3
Reference locus (S288C): YLR401C
Gene biotype: protein_coding
Description: tRNA-dihydrouridine(47) synthase [NAD(P)(+)]; Dihydrouridine synthase; member of a widespread family of conserved proteins including Smm1p, Dus1p, and Dus4p; contains a consensus oleate response element (ORE) in its promoter region; forms nuclear foci upon DNA replication stress; Belongs to the Dus family. Dus3 subfamily
Top 10 interactors (score): ERB1 (0.913); RPA135 (0.893); THS1 (0.887); NCL1 (0.883); TIF5 (0.871); PUS1 (0.861); SUI3 (0.844); PUS7 (0.835); NMD3 (0.833); YTM1 (0.832); NOP2 (0.827); RPA190 (0.818); TRM2 (0.812); TIF35 (0.799); RPA12 (0.793); UTP21 (0.781); NOG1 (0.772); PWP1 (0.748); NOG2 (0.746); BUD20 (0.737)
Homologues (species, bitscore): DUS3L (Homo sapiens, 399.8); Dus3l (Mus musculus, 392.5); dus3l (Danio rerio, 376.3); dus3l (Xenopus tropicalis, 407.5); CG10463 (Drosophila melanogaster, 382.5); Y37E11B.5 (Caenorhabditis elegans, 337.0); AT4G38890 (Arabidopsis thaliana, 355.5)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005306.1:871976-873982:- | gene-YLR401C_AKU4011 | rna-NM_001182289.3_AKU4011 | cds-NP_013505.4_AKU4011 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000048.1:104119-106125:- | gene-YLR401C_BG1 | rna-NM_001182289.3_BG1 | cds-NP_013505.4_BG1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005514.1:910281-912287:- | gene-YLR401C_Bruggeman | rna-NM_001182289.3_Bruggeman | cds-NP_013505.4_Bruggeman | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005530.1:905805-907811:- | gene-YLR401C_CAT1 | rna-NM_001182289.3_CAT1 | cds-NP_013505.4_CAT1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005370.1:907572-909578:- | gene-YLR401C_CBS1585 | rna-NM_001182289.3_CBS1585 | cds-NP_013505.4_CBS1585 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005354.1:891210-893216:- | gene-YLR401C_CBS436 | rna-NM_001182289.3_CBS436 | cds-NP_013505.4_CBS436 | 99.4 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005338.1:943613-945619:- | gene-YLR401C_CBS6412 | rna-NM_001182289.3_CBS6412 | cds-NP_013505.4_CBS6412 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005322.1:907863-909869:- | gene-YLR401C_CBS6413 | rna-NM_001182289.3_CBS6413 | cds-NP_013505.4_CBS6413 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001533.1:907253-909259:- | gene-YLR401C_CENPK1137D | rna-NM_001182289.3_CENPK1137D | cds-NP_013505.4_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005482.1:864519-866525:- | gene-YLR401C_EthanolRed | rna-NM_001182289.3_EthanolRed | cds-NP_013505.4_EthanolRed | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005546.1:893829-895835:- | gene-YLR401C_FaliES1 | rna-NM_001182289.3_FaliES1 | cds-NP_013505.4_FaliES1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000434.1:46988-48994:- | gene-YLR401C_JAY291 | rna-NM_001182289.3_JAY291 | cds-NP_013505.4_JAY291 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005418.1:909147-911153:- | gene-YLR401C_MUCL30387 | rna-NM_001182289.3_MUCL30387 | cds-NP_013505.4_MUCL30387 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005450.1:915233-917239:- | gene-YLR401C_MUCL30388 | rna-NM_001182289.3_MUCL30388 | cds-NP_013505.4_MUCL30388 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005290.1:908792-910798:- | gene-YLR401C_MUCL39482 | rna-NM_001182289.3_MUCL39482 | cds-NP_013505.4_MUCL39482 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005434.1:903447-905453:- | gene-YLR401C_MUCL42920 | rna-NM_001182289.3_MUCL42920 | cds-NP_013505.4_MUCL42920 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011821.1:922416-924422:- | gene-YLR401C_NCIM3186 | rna-NM_001182289.3_NCIM3186 | cds-NP_013505.4_NCIM3186 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005274.1:917972-919978:- | gene-YLR401C_NCYC1407 | rna-NM_001182289.3_NCYC1407 | cds-NP_013505.4_NCYC1407 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994151.1:904369-906375:- | gene-YLR401C_PE2H3 | rna-NM_001182289.3_PE2H3 | cds-NP_013505.4_PE2H3 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999883.1:904113-906119:- | gene-YLR401C_PE2H4 | rna-NM_001182289.3_PE2H4 | cds-NP_013505.4_PE2H4 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001144.5:922442-924448:- | gene-YLR401C_S288C | rna-NM_001182289.3_S288C | cds-NP_013505.4_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000007.1:124241-126247:+ | gene-YLR401C_SA1 | rna-NM_001182289.3_SA1 | cds-NP_013505.4_SA1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005498.1:896908-898914:- | gene-YLR401C_ThermosaccDry | rna-NM_001182289.3_ThermosaccDry | cds-NP_013505.4_ThermosaccDry | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005466.1:909459-911465:- | gene-YLR401C_VR1 | rna-NM_001182289.3_VR1 | cds-NP_013505.4_VR1 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000025.1:233626-235632:- | gene-YLR401C_ZTW1 | rna-NM_001182289.3_ZTW1 | cds-NP_013505.4_ZTW1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047498.1:882353-884365:- | gene-YLR401C_Sparadoxus | rna-NM_001182289.3_Sparadoxus | cds-NP_013505.4_Sparadoxus | 89.9 | 99.9 | Verified | 1 | 1 | 1 | False | True | False | False | False |