Gene name: DUG2
Reference locus (S288C): YBR281C
Gene biotype: protein_coding
Description: Probable di- and tripeptidase DUG2; Component of glutamine amidotransferase (GATase II); forms a complex with Dug3p to degrade glutathione (GSH) and other peptides containing a gamma-glu-X bond in an alternative pathway to GSH degradation by gamma-glutamyl transpeptidase (Ecm38p)
Top 10 interactors (score): DUG3 (0.999); DUG1 (0.951); ECM38 (0.846); ARG5,6 (0.84); GUA1 (0.8); ETP1 (0.677); MTC7 (0.675); PDX3 (0.671); ARG1 (0.667); PRX1 (0.667); SAF1 (0.651); YPL225W (0.641); TRP5 (0.625); OPT1 (0.616); BPH1 (0.61); LAP2 (0.605); CYS4 (0.579); ITC1 (0.569); MON2 (0.56); UTP15 (0.556)
Homologues (species, bitscore): CNDP1 (Homo sapiens, 219.5); Cndp2 (Mus musculus, 206.8); cndp2 (Danio rerio, 206.5); cndp1 (Xenopus tropicalis, 192.6); CG17337 (Drosophila melanogaster, 205.3); pes-9 (Caenorhabditis elegans, 193.0); AT4G17830 (Arabidopsis thaliana, 52.0)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005296.1:749270-751906:- | gene-YBR281C_AKU4011 | rna-NM_001178629.3_AKU4011 | cds-NP_009840.3_AKU4011 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000066.1:120265-122901:- | gene-YBR281C_BG1 | rna-NM_001178629.3_BG1 | cds-NP_009840.3_BG1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005504.1:750404-753040:- | gene-YBR281C_Bruggeman | rna-NM_001178629.3_Bruggeman | cds-NP_009840.3_Bruggeman | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005520.1:754129-756765:- | gene-YBR281C_CAT1 | rna-NM_001178629.3_CAT1 | cds-NP_009840.3_CAT1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005360.1:740836-743472:- | gene-YBR281C_CBS1585 | rna-NM_001178629.3_CBS1585 | cds-NP_009840.3_CBS1585 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005344.1:747252-749888:- | gene-YBR281C_CBS436 | rna-NM_001178629.3_CBS436 | cds-NP_009840.3_CBS436 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005328.1:835451-838087:- | gene-YBR281C_CBS6412 | rna-NM_001178629.3_CBS6412 | cds-NP_009840.3_CBS6412 | 99.6 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005312.1:746884-749520:- | gene-YBR281C_CBS6413 | rna-NM_001178629.3_CBS6413 | cds-NP_009840.3_CBS6413 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001523.1:758870-761506:- | gene-YBR281C_CENPK1137D | rna-NM_001178629.3_CENPK1137D | cds-NP_009840.3_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005472.1:872305-874941:- | gene-YBR281C_EthanolRed | rna-NM_001178629.3_EthanolRed | cds-NP_009840.3_EthanolRed | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005536.1:765652-768288:- | gene-YBR281C_FaliES1 | rna-NM_001178629.3_FaliES1 | cds-NP_009840.3_FaliES1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000067.1:35801-38437:+ | gene-YBR281C_JAY291 | rna-NM_001178629.3_JAY291 | cds-NP_009840.3_JAY291 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005408.1:752447-755083:- | gene-YBR281C_MUCL30387 | rna-NM_001178629.3_MUCL30387 | cds-NP_009840.3_MUCL30387 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005440.1:769529-772165:- | gene-YBR281C_MUCL30388 | rna-NM_001178629.3_MUCL30388 | cds-NP_009840.3_MUCL30388 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005280.1:739143-741779:- | gene-YBR281C_MUCL39482 | rna-NM_001178629.3_MUCL39482 | cds-NP_009840.3_MUCL39482 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005424.1:748991-751627:- | gene-YBR281C_MUCL42920 | rna-NM_001178629.3_MUCL42920 | cds-NP_009840.3_MUCL42920 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011811.1:764767-767403:- | gene-YBR281C_NCIM3186 | rna-NM_001178629.3_NCIM3186 | cds-NP_009840.3_NCIM3186 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005264.1:741032-743668:- | gene-YBR281C_NCYC1407 | rna-NM_001178629.3_NCYC1407 | cds-NP_009840.3_NCYC1407 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994141.1:764130-766766:- | gene-YBR281C_PE2H3 | rna-NM_001178629.3_PE2H3 | cds-NP_009840.3_PE2H3 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999873.1:761806-764442:- | gene-YBR281C_PE2H4 | rna-NM_001178629.3_PE2H4 | cds-NP_009840.3_PE2H4 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001134.8:764970-767606:- | gene-YBR281C_S288C | rna-NM_001178629.3_S288C | cds-NP_009840.3_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000019.1:120085-122721:- | gene-YBR281C_SA1 | rna-NM_001178629.3_SA1 | cds-NP_009840.3_SA1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005488.1:764644-767280:- | gene-YBR281C_ThermosaccDry | rna-NM_001178629.3_ThermosaccDry | cds-NP_009840.3_ThermosaccDry | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005456.1:744830-747466:- | gene-YBR281C_VR1 | rna-NM_001178629.3_VR1 | cds-NP_009840.3_VR1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000003.1:737487-740123:- | gene-YBR281C_ZTW1 | rna-NM_001178629.3_ZTW1 | cds-NP_009840.3_ZTW1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047488.1:781361-783997:- | gene-YBR281C_Sparadoxus | rna-NM_001178629.3_Sparadoxus | cds-NP_009840.3_Sparadoxus | 90.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |