Gene name: DUF1
Reference locus (S288C): YOL087C
Gene biotype: protein_coding
Description: Uncharacterized WD repeat-containing protein YOL087C; Ubiquitin-binding protein of unknown function; contains one WD40 repeat in a beta-propeller fold; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; homolog of human WDR48/UAF1, which is involved in regulating the Fanconi anemia pathway; deletion mutant is sensitive to various chemicals including phenanthroline, sanguinarine, and nordihydroguaiaretic acid
Top 10 interactors (score): UBP13 (0.999); UBP9 (0.999); ELG1 (0.929); UBI4 (0.87); MHP1 (0.761); UBP7 (0.752); UBP11 (0.752); CDC4 (0.749); CPR3 (0.744); RFC1 (0.737); BUD19 (0.711); MRPS9 (0.711); UBP15 (0.699); SPP381 (0.696); RIB7 (0.693); UTP21 (0.691); MPH1 (0.684); CYR1 (0.676); RUB1 (0.671); OTU2 (0.663)
Homologues (species, bitscore): WDR48 (Homo sapiens, 74.7); Wdr48 (Mus musculus, 74.7); wdr48 (Danio rerio, 80.9); wdr48 (Xenopus tropicalis, 79.0); LRS1 (Arabidopsis thaliana, 53.5)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005309.1:138634-141984:- | gene-YOL087C_AKU4011 | rna-NM_001183341.1_AKU4011 | cds-NP_014554.1_AKU4011 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000172.1:103739-107089:- | gene-YOL087C_BG1 | rna-NM_001183341.1_BG1 | cds-NP_014554.1_BG1 | 98.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005517.1:140183-143533:- | gene-YOL087C_Bruggeman | rna-NM_001183341.1_Bruggeman | cds-NP_014554.1_Bruggeman | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005533.1:139514-142864:- | gene-YOL087C_CAT1 | rna-NM_001183341.1_CAT1 | cds-NP_014554.1_CAT1 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005373.1:133046-136396:- | gene-YOL087C_CBS1585 | rna-NM_001183341.1_CBS1585 | cds-NP_014554.1_CBS1585 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005357.1:138320-141670:- | gene-YOL087C_CBS436 | rna-NM_001183341.1_CBS436 | cds-NP_014554.1_CBS436 | 99.4 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005341.1:133202-136552:- | gene-YOL087C_CBS6412 | rna-NM_001183341.1_CBS6412 | cds-NP_014554.1_CBS6412 | 99.4 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005325.1:139909-143259:- | gene-YOL087C_CBS6413 | rna-NM_001183341.1_CBS6413 | cds-NP_014554.1_CBS6413 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001536.1:149252-152602:- | gene-YOL087C_CENPK1137D | rna-NM_001183341.1_CENPK1137D | cds-NP_014554.1_CENPK1137D | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005485.1:136207-139557:- | gene-YOL087C_EthanolRed | rna-NM_001183341.1_EthanolRed | cds-NP_014554.1_EthanolRed | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005549.1:138534-141884:- | gene-YOL087C_FaliES1 | rna-NM_001183341.1_FaliES1 | cds-NP_014554.1_FaliES1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000160.1:1590-4940:+ | gene-YOL087C_JAY291 | rna-NM_001183341.1_JAY291 | cds-NP_014554.1_JAY291 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005421.1:144386-147735:- | gene-YOL087C_MUCL30387 | rna-NM_001183341.1_MUCL30387 | cds-NP_014554.1_MUCL30387 | 99.4 | 99.9 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005453.1:147566-150916:- | gene-YOL087C_MUCL30388 | rna-NM_001183341.1_MUCL30388 | cds-NP_014554.1_MUCL30388 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005293.1:140967-144317:- | gene-YOL087C_MUCL39482 | rna-NM_001183341.1_MUCL39482 | cds-NP_014554.1_MUCL39482 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005437.1:156735-160085:- | gene-YOL087C_MUCL42920 | rna-NM_001183341.1_MUCL42920 | cds-NP_014554.1_MUCL42920 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011824.1:155176-158526:- | gene-YOL087C_NCIM3186 | rna-NM_001183341.1_NCIM3186 | cds-NP_014554.1_NCIM3186 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005277.1:147562-150912:- | gene-YOL087C_NCYC1407 | rna-NM_001183341.1_NCYC1407 | cds-NP_014554.1_NCYC1407 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994154.1:130857-134207:- | gene-YOL087C_PE2H3 | rna-NM_001183341.1_PE2H3 | cds-NP_014554.1_PE2H3 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999886.1:141841-145191:- | gene-YOL087C_PE2H4 | rna-NM_001183341.1_PE2H4 | cds-NP_014554.1_PE2H4 | 98.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001147.6:155287-158637:- | gene-YOL087C_S288C | rna-NM_001183341.1_S288C | cds-NP_014554.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000001.1:123167-126517:- | gene-YOL087C_SA1 | rna-NM_001183341.1_SA1 | cds-NP_014554.1_SA1 | 99.3 | 99.9 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005501.1:137542-140892:- | gene-YOL087C_ThermosaccDry | rna-NM_001183341.1_ThermosaccDry | cds-NP_014554.1_ThermosaccDry | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005469.1:138108-141458:- | gene-YOL087C_VR1 | rna-NM_001183341.1_VR1 | cds-NP_014554.1_VR1 | 98.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000031.1:137240-140590:- | gene-YOL087C_ZTW1 | rna-NM_001183341.1_ZTW1 | cds-NP_014554.1_ZTW1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047501.1:140712-144074:- | gene-YOL087C_Sparadoxus | rna-NM_001183341.1_Sparadoxus | cds-NP_014554.1_Sparadoxus | 89.6 | 99.8 | Verified | 1 | 1 | 1 | False | True | False | False | False |