Gene name: DST1
Reference locus (S288C): YGL043W
Gene biotype: protein_coding
Description: General transcription elongation factor TFIIS; enables RNA polymerase II to read through blocks to elongation by stimulating cleavage of nascent transcripts stalled at transcription arrest sites; maintains RNAPII elongation activity on ribosomal protein genes during conditions of transcriptional stress; Belongs to the TFS-II family
Top 10 interactors (score): SPT5 (0.999); SUA7 (0.999); RPC10 (0.999); SPN1 (0.999); RPB10 (0.999); RPO21 (0.999); RPB9 (0.999); RPO26 (0.999); RPB3 (0.999); SPT4 (0.999); RPB5 (0.999); RPB7 (0.999); RPB4 (0.999); RPB2 (0.999); RPA12 (0.999); RPB11 (0.999); SPT15 (0.999); SPT16 (0.998); TFG2 (0.998); SPT6 (0.994)
Homologues (species, bitscore): TCEA1 (Homo sapiens, 140.6); Tcea1 (Mus musculus, 136.3); tcea1 (Danio rerio, 131.0); tcea1 (Xenopus tropicalis, 124.4); TfIIS (Drosophila melanogaster, 121.7); T24H10.1 (Caenorhabditis elegans, 107.8); TFIIS (Arabidopsis thaliana, 124.8)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005301.1:419552-420481:+ | gene-YGL043W_AKU4011 | rna-NM_001180908.1_AKU4011 | cds-NP_011472.1_AKU4011 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000060.1:155649-156578:- | gene-YGL043W_BG1 | rna-NM_001180908.1_BG1 | cds-NP_011472.1_BG1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005509.1:420374-421303:+ | gene-YGL043W_Bruggeman | rna-NM_001180908.1_Bruggeman | cds-NP_011472.1_Bruggeman | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005525.1:418535-419464:+ | gene-YGL043W_CAT1 | rna-NM_001180908.1_CAT1 | cds-NP_011472.1_CAT1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005365.1:421015-421944:+ | gene-YGL043W_CBS1585 | rna-NM_001180908.1_CBS1585 | cds-NP_011472.1_CBS1585 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005349.1:415153-416082:+ | gene-YGL043W_CBS436 | rna-NM_001180908.1_CBS436 | cds-NP_011472.1_CBS436 | 99.6 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005333.1:413688-414617:+ | gene-YGL043W_CBS6412 | rna-NM_001180908.1_CBS6412 | cds-NP_011472.1_CBS6412 | 99.4 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005317.1:417733-418662:+ | gene-YGL043W_CBS6413 | rna-NM_001180908.1_CBS6413 | cds-NP_011472.1_CBS6413 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001528.1:417324-418253:+ | gene-YGL043W_CENPK1137D | rna-NM_001180908.1_CENPK1137D | cds-NP_011472.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005477.1:407934-408863:+ | gene-YGL043W_EthanolRed | rna-NM_001180908.1_EthanolRed | cds-NP_011472.1_EthanolRed | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005541.1:411196-412125:+ | gene-YGL043W_FaliES1 | rna-NM_001180908.1_FaliES1 | cds-NP_011472.1_FaliES1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000165.1:4706-5635:- | gene-YGL043W_JAY291 | rna-NM_001180908.1_JAY291 | cds-NP_011472.1_JAY291 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005413.1:417330-418259:+ | gene-YGL043W_MUCL30387 | rna-NM_001180908.1_MUCL30387 | cds-NP_011472.1_MUCL30387 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005445.1:420374-421303:+ | gene-YGL043W_MUCL30388 | rna-NM_001180908.1_MUCL30388 | cds-NP_011472.1_MUCL30388 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005285.1:416809-417738:+ | gene-YGL043W_MUCL39482 | rna-NM_001180908.1_MUCL39482 | cds-NP_011472.1_MUCL39482 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005429.1:425227-426156:+ | gene-YGL043W_MUCL42920 | rna-NM_001180908.1_MUCL42920 | cds-NP_011472.1_MUCL42920 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011816.1:417483-418412:+ | gene-YGL043W_NCIM3186 | rna-NM_001180908.1_NCIM3186 | cds-NP_011472.1_NCIM3186 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005269.1:410937-411866:+ | gene-YGL043W_NCYC1407 | rna-NM_001180908.1_NCYC1407 | cds-NP_011472.1_NCYC1407 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994146.1:413512-414441:+ | gene-YGL043W_PE2H3 | rna-NM_001180908.1_PE2H3 | cds-NP_011472.1_PE2H3 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999878.1:418562-419491:+ | gene-YGL043W_PE2H4 | rna-NM_001180908.1_PE2H4 | cds-NP_011472.1_PE2H4 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001139.9:417483-418412:+ | gene-YGL043W_S288C | rna-NM_001180908.1_S288C | cds-NP_011472.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000021.1:137216-138145:- | gene-YGL043W_SA1 | rna-NM_001180908.1_SA1 | cds-NP_011472.1_SA1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005493.1:430560-431489:+ | gene-YGL043W_ThermosaccDry | rna-NM_001180908.1_ThermosaccDry | cds-NP_011472.1_ThermosaccDry | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005461.1:520499-521428:+ | gene-YGL043W_VR1 | rna-NM_001180908.1_VR1 | cds-NP_011472.1_VR1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000014.1:409135-410064:+ | gene-YGL043W_ZTW1 | rna-NM_001180908.1_ZTW1 | cds-NP_011472.1_ZTW1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047493.1:418744-419673:+ | gene-YGL043W_Sparadoxus | rna-NM_001180908.1_Sparadoxus | cds-NP_011472.1_Sparadoxus | 92.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |