Gene name: DSN1
Reference locus (S288C): YIR010W
Gene biotype: protein_coding
Description: Kinetochore-associated protein DSN1; Essential component of the MIND kinetochore complex; joins kinetochore subunits contacting DNA to those contacting microtubules; Dsn1p phosphorylation promotes interaction between outer and inner kinetochore proteins; kinetochore receptor for monopolin, via interaction with subunit Csm1p; essential for meiotic but not mitotic chromosome segregation; MIND complex consists of Mtw1p, Nnf1p, Nsl1p and Dsn1p; modified by sumoylation; phosphorylated by monopolin subunit Hrr25p
Top 10 interactors (score): MTW1 (0.999); NNF1 (0.999); NSL1 (0.999); SPC24 (0.997); SPC25 (0.995); SPC105 (0.992); OKP1 (0.986); CTF19 (0.983); AME1 (0.983); NUF2 (0.98); CSE4 (0.98); KRE28 (0.98); CHL4 (0.977); CTF3 (0.977); MCM21 (0.972); MCM22 (0.97); NKP2 (0.969); CNN1 (0.961); ASK1 (0.954); IML3 (0.951)
Homologues (species, bitscore): Unknown
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
AKU4011 | GCA_001738255.1 | Sake | Asia | CM005303.1:374776-376497:+ | gene-YIR010W_AKU4011 | rna-NM_001179532.3_AKU4011 | cds-NP_012275.3_AKU4011 | 98.9 | 99.3 | Verified | 1 | 1 | 1 | False | True | False | False | False |
BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000072.1:50071-51789:- | gene-YIR010W_BG1 | rna-NM_001179532.3_BG1 | cds-NP_012275.3_BG1 | 99.2 | 99.3 | Verified | 1 | 1 | 1 | False | True | False | False | False |
Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005511.1:379192-380922:+ | gene-YIR010W_Bruggeman | rna-NM_001179532.3_Bruggeman | cds-NP_012275.3_Bruggeman | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005527.1:365917-367635:+ | gene-YIR010W_CAT1 | rna-NM_001179532.3_CAT1 | cds-NP_012275.3_CAT1 | 99.2 | 99.3 | Verified | 1 | 1 | 1 | False | True | False | False | False |
CBS1585 | GCA_001738375.1 | Sake | Asia | CM005367.1:374811-376532:+ | gene-YIR010W_CBS1585 | rna-NM_001179532.3_CBS1585 | cds-NP_012275.3_CBS1585 | 98.9 | 99.3 | Verified | 1 | 1 | 1 | False | True | False | False | False |
CBS436 | GCA_001738355.1 | Sake | Asia | CM005351.1:367472-369202:+ | gene-YIR010W_CBS436 | rna-NM_001179532.3_CBS436 | cds-NP_012275.3_CBS436 | 99.9 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
CBS6412 | GCA_001738345.1 | Sake | Asia | CM005335.1:370294-372015:+ | gene-YIR010W_CBS6412 | rna-NM_001179532.3_CBS6412 | cds-NP_012275.3_CBS6412 | 98.9 | 99.3 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
CBS6413 | GCA_001738265.1 | Sake | Asia | CM005319.1:366891-368609:+ | gene-YIR010W_CBS6413 | rna-NM_001179532.3_CBS6413 | cds-NP_012275.3_CBS6413 | 99.1 | 99.3 | Verified | 1 | 1 | 1 | False | True | False | False | False |
CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001530.1:367490-369220:+ | gene-YIR010W_CENPK1137D | rna-NM_001179532.3_CENPK1137D | cds-NP_012275.3_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005479.1:357860-359581:+ | gene-YIR010W_EthanolRed | rna-NM_001179532.3_EthanolRed | cds-NP_012275.3_EthanolRed | 98.9 | 99.3 | Verified | 1 | 1 | 1 | False | True | False | False | False |
FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005543.1:376587-378308:+ | gene-YIR010W_FaliES1 | rna-NM_001179532.3_FaliES1 | cds-NP_012275.3_FaliES1 | 98.9 | 99.3 | Verified | 1 | 1 | 1 | False | True | False | False | False |
JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000009.1:13657-15375:- | gene-YIR010W_JAY291 | rna-NM_001179532.3_JAY291 | cds-NP_012275.3_JAY291 | 99.2 | 99.3 | Verified | 1 | 1 | 1 | False | True | False | False | False |
MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005415.1:376448-378166:+ | gene-YIR010W_MUCL30387 | rna-NM_001179532.3_MUCL30387 | cds-NP_012275.3_MUCL30387 | 98.9 | 99.3 | Verified | 1 | 1 | 1 | False | True | False | False | False |
MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005447.1:373217-374947:+ | gene-YIR010W_MUCL30388 | rna-NM_001179532.3_MUCL30388 | cds-NP_012275.3_MUCL30388 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005287.1:375446-377167:+ | gene-YIR010W_MUCL39482 | rna-NM_001179532.3_MUCL39482 | cds-NP_012275.3_MUCL39482 | 98.9 | 99.3 | Verified | 1 | 1 | 1 | False | True | False | False | False |
MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005431.1:379015-380733:+ | gene-YIR010W_MUCL42920 | rna-NM_001179532.3_MUCL42920 | cds-NP_012275.3_MUCL42920 | 99.0 | 99.3 | Verified | 1 | 1 | 1 | False | True | False | False | False |
NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011818.1:375431-377161:+ | gene-YIR010W_NCIM3186 | rna-NM_001179532.3_NCIM3186 | cds-NP_012275.3_NCIM3186 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005271.1:379673-381394:+ | gene-YIR010W_NCYC1407 | rna-NM_001179532.3_NCYC1407 | cds-NP_012275.3_NCYC1407 | 98.9 | 99.3 | Verified | 1 | 1 | 1 | False | True | False | False | False |
PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994148.1:369497-371215:+ | gene-YIR010W_PE2H3 | rna-NM_001179532.3_PE2H3 | cds-NP_012275.3_PE2H3 | 99.2 | 99.3 | Verified | 1 | 1 | 1 | False | True | False | False | False |
PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999880.1:364203-365921:+ | gene-YIR010W_PE2H4 | rna-NM_001179532.3_PE2H4 | cds-NP_012275.3_PE2H4 | 99.2 | 99.3 | Verified | 1 | 1 | 1 | False | True | False | False | False |
S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001141.2:375431-377161:+ | gene-YIR010W_S288C | rna-NM_001179532.3_S288C | cds-NP_012275.3_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000066.1:50280-52022:+ | gene-YIR010W_SA1 | rna-NM_001179532.3_SA1 | cds-NP_012275.3_SA1 | 98.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005495.1:374191-375912:+ | gene-YIR010W_ThermosaccDry | rna-NM_001179532.3_ThermosaccDry | cds-NP_012275.3_ThermosaccDry | 98.9 | 99.3 | Verified | 1 | 1 | 1 | False | True | False | False | False |
VR1 | GCA_001738595.1 | Bioethanol | South America | CM005463.1:370270-371988:+ | gene-YIR010W_VR1 | rna-NM_001179532.3_VR1 | cds-NP_012275.3_VR1 | 99.0 | 99.3 | Verified | 1 | 1 | 1 | False | True | False | False | False |
ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000019.1:348190-349908:+ | gene-YIR010W_ZTW1 | rna-NM_001179532.3_ZTW1 | cds-NP_012275.3_ZTW1 | 99.1 | 99.3 | Verified | 1 | 1 | 1 | False | True | False | False | False |
Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047495.1:369623-371317:+ | gene-YIR010W_Sparadoxus | rna-NM_001179532.3_Sparadoxus | cds-NP_012275.3_Sparadoxus | 88.9 | 97.7 | Verified | 1 | 1 | 1 | False | True | False | False | False |