DSN1 (YIR010W)


Gene profile

Gene name: DSN1
Reference locus (S288C): YIR010W
Gene biotype: protein_coding

Description: Kinetochore-associated protein DSN1; Essential component of the MIND kinetochore complex; joins kinetochore subunits contacting DNA to those contacting microtubules; Dsn1p phosphorylation promotes interaction between outer and inner kinetochore proteins; kinetochore receptor for monopolin, via interaction with subunit Csm1p; essential for meiotic but not mitotic chromosome segregation; MIND complex consists of Mtw1p, Nnf1p, Nsl1p and Dsn1p; modified by sumoylation; phosphorylated by monopolin subunit Hrr25p

Top 10 interactors (score): MTW1 (0.999); NNF1 (0.999); NSL1 (0.999); SPC24 (0.997); SPC25 (0.995); SPC105 (0.992); OKP1 (0.986); CTF19 (0.983); AME1 (0.983); NUF2 (0.98); CSE4 (0.98); KRE28 (0.98); CHL4 (0.977); CTF3 (0.977); MCM21 (0.972); MCM22 (0.97); NKP2 (0.969); CNN1 (0.961); ASK1 (0.954); IML3 (0.951)

Homologues (species, bitscore): Unknown

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005303.1:374776-376497:+ gene-YIR010W_AKU4011 rna-NM_001179532.3_AKU4011 cds-NP_012275.3_AKU4011 98.9 99.3 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000072.1:50071-51789:- gene-YIR010W_BG1 rna-NM_001179532.3_BG1 cds-NP_012275.3_BG1 99.2 99.3 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005511.1:379192-380922:+ gene-YIR010W_Bruggeman rna-NM_001179532.3_Bruggeman cds-NP_012275.3_Bruggeman 99.7 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005527.1:365917-367635:+ gene-YIR010W_CAT1 rna-NM_001179532.3_CAT1 cds-NP_012275.3_CAT1 99.2 99.3 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005367.1:374811-376532:+ gene-YIR010W_CBS1585 rna-NM_001179532.3_CBS1585 cds-NP_012275.3_CBS1585 98.9 99.3 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005351.1:367472-369202:+ gene-YIR010W_CBS436 rna-NM_001179532.3_CBS436 cds-NP_012275.3_CBS436 99.9 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005335.1:370294-372015:+ gene-YIR010W_CBS6412 rna-NM_001179532.3_CBS6412 cds-NP_012275.3_CBS6412 98.9 99.3 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005319.1:366891-368609:+ gene-YIR010W_CBS6413 rna-NM_001179532.3_CBS6413 cds-NP_012275.3_CBS6413 99.1 99.3 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001530.1:367490-369220:+ gene-YIR010W_CENPK1137D rna-NM_001179532.3_CENPK1137D cds-NP_012275.3_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005479.1:357860-359581:+ gene-YIR010W_EthanolRed rna-NM_001179532.3_EthanolRed cds-NP_012275.3_EthanolRed 98.9 99.3 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005543.1:376587-378308:+ gene-YIR010W_FaliES1 rna-NM_001179532.3_FaliES1 cds-NP_012275.3_FaliES1 98.9 99.3 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000009.1:13657-15375:- gene-YIR010W_JAY291 rna-NM_001179532.3_JAY291 cds-NP_012275.3_JAY291 99.2 99.3 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005415.1:376448-378166:+ gene-YIR010W_MUCL30387 rna-NM_001179532.3_MUCL30387 cds-NP_012275.3_MUCL30387 98.9 99.3 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005447.1:373217-374947:+ gene-YIR010W_MUCL30388 rna-NM_001179532.3_MUCL30388 cds-NP_012275.3_MUCL30388 99.7 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005287.1:375446-377167:+ gene-YIR010W_MUCL39482 rna-NM_001179532.3_MUCL39482 cds-NP_012275.3_MUCL39482 98.9 99.3 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005431.1:379015-380733:+ gene-YIR010W_MUCL42920 rna-NM_001179532.3_MUCL42920 cds-NP_012275.3_MUCL42920 99.0 99.3 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011818.1:375431-377161:+ gene-YIR010W_NCIM3186 rna-NM_001179532.3_NCIM3186 cds-NP_012275.3_NCIM3186 99.3 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005271.1:379673-381394:+ gene-YIR010W_NCYC1407 rna-NM_001179532.3_NCYC1407 cds-NP_012275.3_NCYC1407 98.9 99.3 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994148.1:369497-371215:+ gene-YIR010W_PE2H3 rna-NM_001179532.3_PE2H3 cds-NP_012275.3_PE2H3 99.2 99.3 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999880.1:364203-365921:+ gene-YIR010W_PE2H4 rna-NM_001179532.3_PE2H4 cds-NP_012275.3_PE2H4 99.2 99.3 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001141.2:375431-377161:+ gene-YIR010W_S288C rna-NM_001179532.3_S288C cds-NP_012275.3_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000066.1:50280-52022:+ gene-YIR010W_SA1 rna-NM_001179532.3_SA1 cds-NP_012275.3_SA1 98.9 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005495.1:374191-375912:+ gene-YIR010W_ThermosaccDry rna-NM_001179532.3_ThermosaccDry cds-NP_012275.3_ThermosaccDry 98.9 99.3 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005463.1:370270-371988:+ gene-YIR010W_VR1 rna-NM_001179532.3_VR1 cds-NP_012275.3_VR1 99.0 99.3 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000019.1:348190-349908:+ gene-YIR010W_ZTW1 rna-NM_001179532.3_ZTW1 cds-NP_012275.3_ZTW1 99.1 99.3 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047495.1:369623-371317:+ gene-YIR010W_Sparadoxus rna-NM_001179532.3_Sparadoxus cds-NP_012275.3_Sparadoxus 88.9 97.7 Verified 1 1 1 False True False False False

Additional files