Gene name: DSL1
Reference locus (S288C): YNL258C
Gene biotype: protein_coding
Description: Peripheral membrane protein needed for Golgi-to-ER retrograde traffic; mediates Sey1p-independent homotypic ER fusion; forms Dsl1 tethering complex with Sec39p and Tip20p that forms a stable complex with ER SNAREs Sec20p, Ufe1p and Use1p and is functionally conserved from yeast to mammalian cells; component of the ER target site that interacts with coatomer; interacts with different subunits of COPI vesicle coat; interacts with Cin5p; homolog of fly and human ZW10 gene
Top 10 interactors (score): TIP20 (0.999); SEC39 (0.999); SEC20 (0.992); UFE1 (0.99); USE1 (0.99); RET2 (0.967); SEC22 (0.958); COP1 (0.942); YPT1 (0.916); SLY1 (0.902); SEC21 (0.871); COG4 (0.861); SEC17 (0.858); RET3 (0.831); SEC26 (0.831); SEC18 (0.825); EXO70 (0.813); SEC27 (0.776); SEC6 (0.768); COG8 (0.766)
Homologues (species, bitscore): Unknown
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005308.1:151879-154143:- | gene-YNL258C_AKU4011 | rna-NM_001183096.1_AKU4011 | cds-NP_014141.1_AKU4011 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000155.1:55837-58101:- | gene-YNL258C_BG1 | rna-NM_001183096.1_BG1 | cds-NP_014141.1_BG1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005516.1:161702-163966:- | gene-YNL258C_Bruggeman | rna-NM_001183096.1_Bruggeman | cds-NP_014141.1_Bruggeman | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005532.1:168997-171261:- | gene-YNL258C_CAT1 | rna-NM_001183096.1_CAT1 | cds-NP_014141.1_CAT1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005372.1:152279-154543:- | gene-YNL258C_CBS1585 | rna-NM_001183096.1_CBS1585 | cds-NP_014141.1_CBS1585 | 98.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005356.1:147381-149645:- | gene-YNL258C_CBS436 | rna-NM_001183096.1_CBS436 | cds-NP_014141.1_CBS436 | 99.9 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005340.1:148690-150954:- | gene-YNL258C_CBS6412 | rna-NM_001183096.1_CBS6412 | cds-NP_014141.1_CBS6412 | 99.4 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005324.1:148972-151236:- | gene-YNL258C_CBS6413 | rna-NM_001183096.1_CBS6413 | cds-NP_014141.1_CBS6413 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001535.1:151923-154187:- | gene-YNL258C_CENPK1137D | rna-NM_001183096.1_CENPK1137D | cds-NP_014141.1_CENPK1137D | 98.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005484.1:149530-151794:- | gene-YNL258C_EthanolRed | rna-NM_001183096.1_EthanolRed | cds-NP_014141.1_EthanolRed | 98.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005548.1:144265-146529:- | gene-YNL258C_FaliES1 | rna-NM_001183096.1_FaliES1 | cds-NP_014141.1_FaliES1 | 98.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000082.1:55434-57698:- | gene-YNL258C_JAY291 | rna-NM_001183096.1_JAY291 | cds-NP_014141.1_JAY291 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005420.1:157486-159750:- | gene-YNL258C_MUCL30387 | rna-NM_001183096.1_MUCL30387 | cds-NP_014141.1_MUCL30387 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005452.1:156071-158335:- | gene-YNL258C_MUCL30388 | rna-NM_001183096.1_MUCL30388 | cds-NP_014141.1_MUCL30388 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005292.1:149769-152033:- | gene-YNL258C_MUCL39482 | rna-NM_001183096.1_MUCL39482 | cds-NP_014141.1_MUCL39482 | 98.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005436.1:152037-154301:- | gene-YNL258C_MUCL42920 | rna-NM_001183096.1_MUCL42920 | cds-NP_014141.1_MUCL42920 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011823.1:158078-160342:- | gene-YNL258C_NCIM3186 | rna-NM_001183096.1_NCIM3186 | cds-NP_014141.1_NCIM3186 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005276.1:151874-154138:- | gene-YNL258C_NCYC1407 | rna-NM_001183096.1_NCYC1407 | cds-NP_014141.1_NCYC1407 | 98.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994153.1:148775-151039:- | gene-YNL258C_PE2H3 | rna-NM_001183096.1_PE2H3 | cds-NP_014141.1_PE2H3 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999885.1:148163-150427:- | gene-YNL258C_PE2H4 | rna-NM_001183096.1_PE2H4 | cds-NP_014141.1_PE2H4 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001146.8:158109-160373:- | gene-YNL258C_S288C | rna-NM_001183096.1_S288C | cds-NP_014141.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000040.1:91917-94181:+ | gene-YNL258C_SA1 | rna-NM_001183096.1_SA1 | cds-NP_014141.1_SA1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005500.1:145121-147385:- | gene-YNL258C_ThermosaccDry | rna-NM_001183096.1_ThermosaccDry | cds-NP_014141.1_ThermosaccDry | 98.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005468.1:164033-166297:- | gene-YNL258C_VR1 | rna-NM_001183096.1_VR1 | cds-NP_014141.1_VR1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000030.1:55453-57717:- | gene-YNL258C_ZTW1 | rna-NM_001183096.1_ZTW1 | cds-NP_014141.1_ZTW1 | 98.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047500.1:155338-157602:- | gene-YNL258C_Sparadoxus | rna-NM_001183096.1_Sparadoxus | cds-NP_014141.1_Sparadoxus | 88.2 | 99.6 | Verified | 1 | 1 | 1 | False | True | False | False | False |