DSK2 (YMR276W)


Gene profile

Gene name: DSK2
Reference locus (S288C): YMR276W
Gene biotype: protein_coding

Description: Nuclear-enriched ubiquitin-like polyubiquitin-binding protein; required for spindle pole body (SPB) duplication and for transit through the G2/M phase of the cell cycle; involved in proteolysis; interacts with the proteasome; protein abundance increases in response to DNA replication stress

Top 10 interactors (score): UFD2 (0.999); RPN10 (0.999); RAD23 (0.999); RPN13 (0.999); RPN1 (0.996); ATG8 (0.996); UBI4 (0.996); DDI1 (0.994); CDC48 (0.994); RPN11 (0.986); RPT1 (0.977); UBP6 (0.97); RPN9 (0.952); RPL40B (0.947); UBA1 (0.931); UFD1 (0.922); NPL4 (0.919); RPS31 (0.918); PTH2 (0.915); RPN12 (0.902)

Homologues (species, bitscore): UBQLN1 (Homo sapiens, 102.8); Ubqln2 (Mus musculus, 104.0); ubqln4 (Danio rerio, 102.1); ubqln4 (Xenopus tropicalis, 99.4); Ubqn (Drosophila melanogaster, 78.6); ubql-1 (Caenorhabditis elegans, 102.8); AT2G17190 (Arabidopsis thaliana, 105.5)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005307.1:857908-859029:+ gene-YMR276W_AKU4011 rna-NM_001182783.1_AKU4011 cds-NP_014003.1_AKU4011 99.1 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000069.1:94628-95749:- gene-YMR276W_BG1 rna-NM_001182783.1_BG1 cds-NP_014003.1_BG1 99.8 100.0 Verified 1 1 1 True True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005515.1:803118-804239:+ gene-YMR276W_Bruggeman rna-NM_001182783.1_Bruggeman cds-NP_014003.1_Bruggeman 99.8 100.0 Verified 1 1 1 True True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005531.1:806404-807525:+ gene-YMR276W_CAT1 rna-NM_001182783.1_CAT1 cds-NP_014003.1_CAT1 99.8 100.0 Verified 1 1 1 True True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005371.1:790158-791279:+ gene-YMR276W_CBS1585 rna-NM_001182783.1_CBS1585 cds-NP_014003.1_CBS1585 99.1 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005355.1:812463-813584:+ gene-YMR276W_CBS436 rna-NM_001182783.1_CBS436 cds-NP_014003.1_CBS436 99.8 100.0 Mismatch 1 1 1 True True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005339.1:901732-902853:+ gene-YMR276W_CBS6412 rna-NM_001182783.1_CBS6412 cds-NP_014003.1_CBS6412 99.1 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005323.1:789279-790400:+ gene-YMR276W_CBS6413 rna-NM_001182783.1_CBS6413 cds-NP_014003.1_CBS6413 99.0 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001534.1:813403-814524:+ gene-YMR276W_CENPK1137D rna-NM_001182783.1_CENPK1137D cds-NP_014003.1_CENPK1137D 99.1 100.0 Verified 1 1 1 False True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005486.1:850598-851719:+ gene-YMR276W_EthanolRed rna-NM_001182783.1_EthanolRed cds-NP_014003.1_EthanolRed 99.1 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005547.1:796625-797746:+ gene-YMR276W_FaliES1 rna-NM_001182783.1_FaliES1 cds-NP_014003.1_FaliES1 99.1 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000262.1:53997-55118:- gene-YMR276W_JAY291 rna-NM_001182783.1_JAY291 cds-NP_014003.1_JAY291 99.8 100.0 Verified 1 1 1 True True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005419.1:796943-798064:+ gene-YMR276W_MUCL30387 rna-NM_001182783.1_MUCL30387 cds-NP_014003.1_MUCL30387 99.6 100.0 Verified 1 1 1 True True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005451.1:806339-807460:+ gene-YMR276W_MUCL30388 rna-NM_001182783.1_MUCL30388 cds-NP_014003.1_MUCL30388 99.8 100.0 Verified 1 1 1 True True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005291.1:791246-792367:+ gene-YMR276W_MUCL39482 rna-NM_001182783.1_MUCL39482 cds-NP_014003.1_MUCL39482 99.1 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005435.1:799314-800435:+ gene-YMR276W_MUCL42920 rna-NM_001182783.1_MUCL42920 cds-NP_014003.1_MUCL42920 99.4 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011822.1:818781-819902:+ gene-YMR276W_NCIM3186 rna-NM_001182783.1_NCIM3186 cds-NP_014003.1_NCIM3186 99.1 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005275.1:790889-792010:+ gene-YMR276W_NCYC1407 rna-NM_001182783.1_NCYC1407 cds-NP_014003.1_NCYC1407 99.1 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994152.1:806684-807805:+ gene-YMR276W_PE2H3 rna-NM_001182783.1_PE2H3 cds-NP_014003.1_PE2H3 99.8 100.0 Verified 1 1 1 True True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999884.1:802670-803791:+ gene-YMR276W_PE2H4 rna-NM_001182783.1_PE2H4 cds-NP_014003.1_PE2H4 100.0 100.0 Verified 1 1 1 True True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001145.3:818827-819948:+ gene-YMR276W_S288C rna-NM_001182783.1_S288C cds-NP_014003.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000114.1:10650-11771:+ gene-YMR276W_SA1 rna-NM_001182783.1_SA1 cds-NP_014003.1_SA1 99.1 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005499.1:792794-793915:+ gene-YMR276W_ThermosaccDry rna-NM_001182783.1_ThermosaccDry cds-NP_014003.1_ThermosaccDry 99.1 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005467.1:806038-807159:+ gene-YMR276W_VR1 rna-NM_001182783.1_VR1 cds-NP_014003.1_VR1 99.7 100.0 Verified 1 1 1 True True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000028.1:208023-209144:+ gene-YMR276W_ZTW1 rna-NM_001182783.1_ZTW1 cds-NP_014003.1_ZTW1 99.1 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047499.1:811232-812365:+ gene-YMR276W_Sparadoxus rna-NM_001182783.1_Sparadoxus cds-NP_014003.1_Sparadoxus 90.5 99.9 Verified 1 1 1 False True False False False

Additional files