Gene name: DSC2
Reference locus (S288C): YOL073C
Gene biotype: protein_coding
Description: Uncharacterized membrane protein YOL073C; Multi-transmembrane subunit of the DSC ubiquitin ligase complex; similar in sequence to rhomboid pseudoproteases Der1p and UBAC2 that function in ERAD; ortholog of fission yeast dsc2
Top 10 interactors (score): TUL1 (0.999); UBX3 (0.999); YPR109W (0.989); UBX2 (0.986); CDC48 (0.97); DSC3 (0.97); YOL107W (0.887); YLR345W (0.837); TRM2 (0.787); FBP26 (0.786); CGR1 (0.719); HMS1 (0.718); BRX1 (0.708); DER1 (0.697); RBD2 (0.663); SER1 (0.662); HRD1 (0.652); LOT5 (0.651); GYP7 (0.646); AFG2 (0.644)
Homologues (species, bitscore): Unknown
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005309.1:177473-178441:- | gene-YOL073C_AKU4011 | rna-NM_001183328.1_AKU4011 | cds-NP_014568.1_AKU4011 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000172.1:142280-143248:- | gene-YOL073C_BG1 | rna-NM_001183328.1_BG1 | cds-NP_014568.1_BG1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005517.1:179157-180125:- | gene-YOL073C_Bruggeman | rna-NM_001183328.1_Bruggeman | cds-NP_014568.1_Bruggeman | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005533.1:178651-179619:- | gene-YOL073C_CAT1 | rna-NM_001183328.1_CAT1 | cds-NP_014568.1_CAT1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005373.1:171866-172834:- | gene-YOL073C_CBS1585 | rna-NM_001183328.1_CBS1585 | cds-NP_014568.1_CBS1585 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005357.1:177046-178014:- | gene-YOL073C_CBS436 | rna-NM_001183328.1_CBS436 | cds-NP_014568.1_CBS436 | 99.5 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005341.1:171794-172762:- | gene-YOL073C_CBS6412 | rna-NM_001183328.1_CBS6412 | cds-NP_014568.1_CBS6412 | 99.5 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005325.1:178729-179697:- | gene-YOL073C_CBS6413 | rna-NM_001183328.1_CBS6413 | cds-NP_014568.1_CBS6413 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001536.1:193586-194554:- | gene-YOL073C_CENPK1137D | rna-NM_001183328.1_CENPK1137D | cds-NP_014568.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005485.1:174788-175756:- | gene-YOL073C_EthanolRed | rna-NM_001183328.1_EthanolRed | cds-NP_014568.1_EthanolRed | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005549.1:177115-178083:- | gene-YOL073C_FaliES1 | rna-NM_001183328.1_FaliES1 | cds-NP_014568.1_FaliES1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000018.1:87459-88427:+ | gene-YOL073C_JAY291 | rna-NM_001183328.1_JAY291 | cds-NP_014568.1_JAY291 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005421.1:182927-183895:- | gene-YOL073C_MUCL30387 | rna-NM_001183328.1_MUCL30387 | cds-NP_014568.1_MUCL30387 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005453.1:186607-187575:- | gene-YOL073C_MUCL30388 | rna-NM_001183328.1_MUCL30388 | cds-NP_014568.1_MUCL30388 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005293.1:179787-180755:- | gene-YOL073C_MUCL39482 | rna-NM_001183328.1_MUCL39482 | cds-NP_014568.1_MUCL39482 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005437.1:195279-196247:- | gene-YOL073C_MUCL42920 | rna-NM_001183328.1_MUCL42920 | cds-NP_014568.1_MUCL42920 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011824.1:193721-194689:- | gene-YOL073C_NCIM3186 | rna-NM_001183328.1_NCIM3186 | cds-NP_014568.1_NCIM3186 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005277.1:186407-187375:- | gene-YOL073C_NCYC1407 | rna-NM_001183328.1_NCYC1407 | cds-NP_014568.1_NCYC1407 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994154.1:169399-170367:- | gene-YOL073C_PE2H3 | rna-NM_001183328.1_PE2H3 | cds-NP_014568.1_PE2H3 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999886.1:180388-181356:- | gene-YOL073C_PE2H4 | rna-NM_001183328.1_PE2H4 | cds-NP_014568.1_PE2H4 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001147.6:193832-194800:- | gene-YOL073C_S288C | rna-NM_001183328.1_S288C | cds-NP_014568.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000001.1:161713-162681:- | gene-YOL073C_SA1 | rna-NM_001183328.1_SA1 | cds-NP_014568.1_SA1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005501.1:176123-177091:- | gene-YOL073C_ThermosaccDry | rna-NM_001183328.1_ThermosaccDry | cds-NP_014568.1_ThermosaccDry | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005469.1:176899-177867:- | gene-YOL073C_VR1 | rna-NM_001183328.1_VR1 | cds-NP_014568.1_VR1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000031.1:175786-176754:- | gene-YOL073C_ZTW1 | rna-NM_001183328.1_ZTW1 | cds-NP_014568.1_ZTW1 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047501.1:179351-180319:- | gene-YOL073C_Sparadoxus | rna-NM_001183328.1_Sparadoxus | cds-NP_014568.1_Sparadoxus | 89.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |