Gene name: DRN1
Reference locus (S288C): YGR093W
Gene biotype: protein_coding
Description: CWF19-like protein DRN1; Splicing factor that modulates turnover of branched RNAs by Dbr1p; interacts with spliceosomal components and branched RNA splicing products; enhances Dbr1p debranching in vitro; conserved protein with domain organization identical from yeast to human; N-terminal homology to Dbr1p N-terminus, but Dbr1p catalytic residues not conserved; relocalizes to the cytosol in response to hypoxia
Top 10 interactors (score): CEF1 (0.999); PRP19 (0.986); DBR1 (0.975); CDC40 (0.969); CWC2 (0.907); SYF1 (0.886); BUD31 (0.814); LEA1 (0.795); CWC22 (0.783); PRP16 (0.756); YOR034C-A (0.746); YBL029W (0.746); PRP22 (0.736); YGR161W-C (0.713); DSC3 (0.712); YIL014C-A (0.712); STB6 (0.711); ILS1 (0.71); NNR1 (0.706); SPP382 (0.705)
Homologues (species, bitscore): CWF19L1 (Homo sapiens, 126.3); Cwf19l1 (Mus musculus, 127.5); cwf19l1 (Danio rerio, 112.8); cwf19l1 (Xenopus tropicalis, 106.7); CG7741 (Drosophila melanogaster, 110.5); F17A9.2 (Caenorhabditis elegans, 95.9); AT5G56900 (Arabidopsis thaliana, 110.9)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005301.1:654568-656091:+ | gene-YGR093W_AKU4011 | rna-NM_001181222.3_AKU4011 | cds-NP_011607.3_AKU4011 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000173.1:90375-91898:+ | gene-YGR093W_BG1 | rna-NM_001181222.3_BG1 | cds-NP_011607.3_BG1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005509.1:656758-658281:+ | gene-YGR093W_Bruggeman | rna-NM_001181222.3_Bruggeman | cds-NP_011607.3_Bruggeman | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005525.1:654948-656471:+ | gene-YGR093W_CAT1 | rna-NM_001181222.3_CAT1 | cds-NP_011607.3_CAT1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005365.1:655532-657055:+ | gene-YGR093W_CBS1585 | rna-NM_001181222.3_CBS1585 | cds-NP_011607.3_CBS1585 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005349.1:657192-658715:+ | gene-YGR093W_CBS436 | rna-NM_001181222.3_CBS436 | cds-NP_011607.3_CBS436 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005333.1:647225-648748:+ | gene-YGR093W_CBS6412 | rna-NM_001181222.3_CBS6412 | cds-NP_011607.3_CBS6412 | 99.2 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005317.1:652167-653690:+ | gene-YGR093W_CBS6413 | rna-NM_001181222.3_CBS6413 | cds-NP_011607.3_CBS6413 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001528.1:670065-671588:+ | gene-YGR093W_CENPK1137D | rna-NM_001181222.3_CENPK1137D | cds-NP_011607.3_CENPK1137D | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005477.1:642119-643642:+ | gene-YGR093W_EthanolRed | rna-NM_001181222.3_EthanolRed | cds-NP_011607.3_EthanolRed | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005541.1:645964-647487:+ | gene-YGR093W_FaliES1 | rna-NM_001181222.3_FaliES1 | cds-NP_011607.3_FaliES1 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000396.1:29067-30590:- | gene-YGR093W_JAY291 | rna-NM_001181222.3_JAY291 | cds-NP_011607.3_JAY291 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005413.1:653746-655269:+ | gene-YGR093W_MUCL30387 | rna-NM_001181222.3_MUCL30387 | cds-NP_011607.3_MUCL30387 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005445.1:656558-658081:+ | gene-YGR093W_MUCL30388 | rna-NM_001181222.3_MUCL30388 | cds-NP_011607.3_MUCL30388 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005285.1:651260-652783:+ | gene-YGR093W_MUCL39482 | rna-NM_001181222.3_MUCL39482 | cds-NP_011607.3_MUCL39482 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005429.1:661570-663093:+ | gene-YGR093W_MUCL42920 | rna-NM_001181222.3_MUCL42920 | cds-NP_011607.3_MUCL42920 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011816.1:670388-671911:+ | gene-YGR093W_NCIM3186 | rna-NM_001181222.3_NCIM3186 | cds-NP_011607.3_NCIM3186 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005269.1:645949-647472:+ | gene-YGR093W_NCYC1407 | rna-NM_001181222.3_NCYC1407 | cds-NP_011607.3_NCYC1407 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994146.1:648638-650161:+ | gene-YGR093W_PE2H3 | rna-NM_001181222.3_PE2H3 | cds-NP_011607.3_PE2H3 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999878.1:653758-655281:+ | gene-YGR093W_PE2H4 | rna-NM_001181222.3_PE2H4 | cds-NP_011607.3_PE2H4 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001139.9:670388-671911:+ | gene-YGR093W_S288C | rna-NM_001181222.3_S288C | cds-NP_011607.3_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000015.1:96962-98485:+ | gene-YGR093W_SA1 | rna-NM_001181222.3_SA1 | cds-NP_011607.3_SA1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005493.1:666334-667857:+ | gene-YGR093W_ThermosaccDry | rna-NM_001181222.3_ThermosaccDry | cds-NP_011607.3_ThermosaccDry | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005461.1:762828-764351:+ | gene-YGR093W_VR1 | rna-NM_001181222.3_VR1 | cds-NP_011607.3_VR1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000015.1:120584-122107:+ | gene-YGR093W_ZTW1 | rna-NM_001181222.3_ZTW1 | cds-NP_011607.3_ZTW1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047493.1:656396-657919:+ | gene-YGR093W_Sparadoxus | rna-NM_001181222.3_Sparadoxus | cds-NP_011607.3_Sparadoxus | 86.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |