Gene name: DRE2
Reference locus (S288C): YKR071C
Gene biotype: protein_coding
Description: Component of the cytosolic Fe-S protein assembly (CIA) machinery; contains an Fe-S cluster that receives electrons from NADPH via the action of Tah18p in an early step in the CIA pathway; ortholog of human Ciapin1; protein abundance increases in response to DNA replication stress; inviability of the null mutant is functionally complemented by human CIAPIN1; Belongs to the anamorsin family
Top 10 interactors (score): TAH18 (0.999); NBP35 (0.999); GRX3 (0.998); CFD1 (0.997); GRX4 (0.996); NAR1 (0.994); BOL1 (0.992); GRX5 (0.992); MET18 (0.99); BOL2 (0.984); BOL3 (0.975); ATM1 (0.953); CIA2 (0.949); RLI1 (0.946); MIA40 (0.939); ISD11 (0.908); CIA1 (0.899); IBA57 (0.899); JAC1 (0.893); YAH1 (0.889)
Homologues (species, bitscore): CIAPIN1 (Homo sapiens, 85.5); Ciapin1 (Mus musculus, 87.0); ciapin1 (Danio rerio, 82.4); ciapin1 (Xenopus tropicalis, 88.6); CIAPIN1 (Drosophila melanogaster, 84.0); T20B12.7 (Caenorhabditis elegans, 80.5); AT5G18400 (Arabidopsis thaliana, 70.9)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005305.1:560979-562025:- | gene-YKR071C_AKU4011 | rna-NM_001179861.3_AKU4011 | cds-NP_012997.3_AKU4011 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000113.1:82252-83298:+ | gene-YKR071C_BG1 | rna-NM_001179861.3_BG1 | cds-NP_012997.3_BG1 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005513.1:582417-583463:- | gene-YKR071C_Bruggeman | rna-NM_001179861.3_Bruggeman | cds-NP_012997.3_Bruggeman | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005529.1:578824-579870:- | gene-YKR071C_CAT1 | rna-NM_001179861.3_CAT1 | cds-NP_012997.3_CAT1 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005369.1:573472-574518:- | gene-YKR071C_CBS1585 | rna-NM_001179861.3_CBS1585 | cds-NP_012997.3_CBS1585 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005353.1:571800-572846:- | gene-YKR071C_CBS436 | rna-NM_001179861.3_CBS436 | cds-NP_012997.3_CBS436 | 99.0 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005337.1:556760-557806:- | gene-YKR071C_CBS6412 | rna-NM_001179861.3_CBS6412 | cds-NP_012997.3_CBS6412 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005321.1:573290-574336:- | gene-YKR071C_CBS6413 | rna-NM_001179861.3_CBS6413 | cds-NP_012997.3_CBS6413 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001532.1:574600-575646:- | gene-YKR071C_CENPK1137D | rna-NM_001179861.3_CENPK1137D | cds-NP_012997.3_CENPK1137D | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005481.1:570289-571335:- | gene-YKR071C_EthanolRed | rna-NM_001179861.3_EthanolRed | cds-NP_012997.3_EthanolRed | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005545.1:574189-575235:- | gene-YKR071C_FaliES1 | rna-NM_001179861.3_FaliES1 | cds-NP_012997.3_FaliES1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000410.1:3003-4049:+ | gene-YKR071C_JAY291 | rna-NM_001179861.3_JAY291 | cds-NP_012997.3_JAY291 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005417.1:582801-583847:- | gene-YKR071C_MUCL30387 | rna-NM_001179861.3_MUCL30387 | cds-NP_012997.3_MUCL30387 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005449.1:577401-578447:- | gene-YKR071C_MUCL30388 | rna-NM_001179861.3_MUCL30388 | cds-NP_012997.3_MUCL30388 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005289.1:572301-573347:- | gene-YKR071C_MUCL39482 | rna-NM_001179861.3_MUCL39482 | cds-NP_012997.3_MUCL39482 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005433.1:578324-579370:- | gene-YKR071C_MUCL42920 | rna-NM_001179861.3_MUCL42920 | cds-NP_012997.3_MUCL42920 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011820.1:574923-575969:- | gene-YKR071C_NCIM3186 | rna-NM_001179861.3_NCIM3186 | cds-NP_012997.3_NCIM3186 | 98.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005273.1:572722-573768:- | gene-YKR071C_NCYC1407 | rna-NM_001179861.3_NCYC1407 | cds-NP_012997.3_NCYC1407 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994150.1:597878-598924:- | gene-YKR071C_PE2H3 | rna-NM_001179861.3_PE2H3 | cds-NP_012997.3_PE2H3 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999882.1:582262-583308:- | gene-YKR071C_PE2H4 | rna-NM_001179861.3_PE2H4 | cds-NP_012997.3_PE2H4 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001143.9:574934-575980:- | gene-YKR071C_S288C | rna-NM_001179861.3_S288C | cds-NP_012997.3_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000029.1:105865-106911:+ | gene-YKR071C_SA1 | rna-NM_001179861.3_SA1 | cds-NP_012997.3_SA1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005497.1:573428-574474:- | gene-YKR071C_ThermosaccDry | rna-NM_001179861.3_ThermosaccDry | cds-NP_012997.3_ThermosaccDry | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005465.1:573188-574234:- | gene-YKR071C_VR1 | rna-NM_001179861.3_VR1 | cds-NP_012997.3_VR1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000022.1:570916-571962:- | gene-YKR071C_ZTW1 | rna-NM_001179861.3_ZTW1 | cds-NP_012997.3_ZTW1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047497.1:596322-597368:- | gene-YKR071C_Sparadoxus | rna-NM_001179861.3_Sparadoxus | cds-NP_012997.3_Sparadoxus | 86.7 | 99.7 | Verified | 1 | 1 | 1 | False | True | False | False | False |