Gene name: DPS1
Reference locus (S288C): YLL018C
Gene biotype: protein_coding
Description: Aspartate--tRNA ligase, cytoplasmic; Aspartyl-tRNA synthetase, primarily cytoplasmic; homodimeric enzyme that catalyzes the specific aspartylation of tRNA(Asp); class II aminoacyl tRNA synthetase; binding to its own mRNA may confer autoregulation; shares five highly conserved amino acids with human that when mutated cause leukoencephalopathy characterized by hypomyelination with brain stem and spinal cord involvement and leg spasticity (HBSL); Belongs to the class-II aminoacyl-tRNA synthetase family. Type 2 subfamily
Top 10 interactors (score): GUS1 (0.999); ILS1 (0.998); CDC60 (0.997); GLN4 (0.997); ARC1 (0.996); YHR020W (0.995); MES1 (0.995); KRS1 (0.983); FRS1 (0.967); PCH2 (0.962); YDR341C (0.959); TYS1 (0.943); THS1 (0.929); MSD1 (0.904); SUI2 (0.885); GRS1 (0.877); RPT4 (0.876); ADE12 (0.865); GRS2 (0.864); AIM10 (0.861)
Homologues (species, bitscore): DARS (Homo sapiens, 560.5); Dars (Mus musculus, 555.1); dars (Danio rerio, 585.9); dars (Xenopus tropicalis, 585.5); Aats-asp (Drosophila melanogaster, 545.0); dars-1 (Caenorhabditis elegans, 532.7); AT4G31180 (Arabidopsis thaliana, 463.0)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005306.1:97648-99321:- | gene-YLL018C_AKU4011 | rna-NM_001181838.1_AKU4011 | cds-NP_013083.1_AKU4011 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000212.1:61144-62817:- | gene-YLL018C_BG1 | rna-NM_001181838.1_BG1 | cds-NP_013083.1_BG1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005514.1:107478-109151:- | gene-YLL018C_Bruggeman | rna-NM_001181838.1_Bruggeman | cds-NP_013083.1_Bruggeman | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005530.1:108343-110016:- | gene-YLL018C_CAT1 | rna-NM_001181838.1_CAT1 | cds-NP_013083.1_CAT1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005370.1:105245-106918:- | gene-YLL018C_CBS1585 | rna-NM_001181838.1_CBS1585 | cds-NP_013083.1_CBS1585 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005354.1:95619-97292:- | gene-YLL018C_CBS436 | rna-NM_001181838.1_CBS436 | cds-NP_013083.1_CBS436 | 99.5 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005338.1:104008-105681:- | gene-YLL018C_CBS6412 | rna-NM_001181838.1_CBS6412 | cds-NP_013083.1_CBS6412 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005322.1:105507-107180:- | gene-YLL018C_CBS6413 | rna-NM_001181838.1_CBS6413 | cds-NP_013083.1_CBS6413 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001533.1:94926-96599:- | gene-YLL018C_CENPK1137D | rna-NM_001181838.1_CENPK1137D | cds-NP_013083.1_CENPK1137D | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005482.1:97688-99361:- | gene-YLL018C_EthanolRed | rna-NM_001181838.1_EthanolRed | cds-NP_013083.1_EthanolRed | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005546.1:97259-98932:- | gene-YLL018C_FaliES1 | rna-NM_001181838.1_FaliES1 | cds-NP_013083.1_FaliES1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000083.1:56426-58099:+ | gene-YLL018C_JAY291 | rna-NM_001181838.1_JAY291 | cds-NP_013083.1_JAY291 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005418.1:105370-107043:- | gene-YLL018C_MUCL30387 | rna-NM_001181838.1_MUCL30387 | cds-NP_013083.1_MUCL30387 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005450.1:109600-111273:- | gene-YLL018C_MUCL30388 | rna-NM_001181838.1_MUCL30388 | cds-NP_013083.1_MUCL30388 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005290.1:105715-107388:- | gene-YLL018C_MUCL39482 | rna-NM_001181838.1_MUCL39482 | cds-NP_013083.1_MUCL39482 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005434.1:105390-107063:- | gene-YLL018C_MUCL42920 | rna-NM_001181838.1_MUCL42920 | cds-NP_013083.1_MUCL42920 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011821.1:109876-111549:- | gene-YLL018C_NCIM3186 | rna-NM_001181838.1_NCIM3186 | cds-NP_013083.1_NCIM3186 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005274.1:97326-98999:- | gene-YLL018C_NCYC1407 | rna-NM_001181838.1_NCYC1407 | cds-NP_013083.1_NCYC1407 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994151.1:103684-105357:- | gene-YLL018C_PE2H3 | rna-NM_001181838.1_PE2H3 | cds-NP_013083.1_PE2H3 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999883.1:103418-105091:- | gene-YLL018C_PE2H4 | rna-NM_001181838.1_PE2H4 | cds-NP_013083.1_PE2H4 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001144.5:109902-111575:- | gene-YLL018C_S288C | rna-NM_001181838.1_S288C | cds-NP_013083.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000062.1:12821-14494:- | gene-YLL018C_SA1 | rna-NM_001181838.1_SA1 | cds-NP_013083.1_SA1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005498.1:97765-99438:- | gene-YLL018C_ThermosaccDry | rna-NM_001181838.1_ThermosaccDry | cds-NP_013083.1_ThermosaccDry | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005466.1:111417-113090:- | gene-YLL018C_VR1 | rna-NM_001181838.1_VR1 | cds-NP_013083.1_VR1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000023.1:97082-98755:- | gene-YLL018C_ZTW1 | rna-NM_001181838.1_ZTW1 | cds-NP_013083.1_ZTW1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047498.1:105476-107149:- | gene-YLL018C_Sparadoxus | rna-NM_001181838.1_Sparadoxus | cds-NP_013083.1_Sparadoxus | 93.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |