DPM1 (YPR183W)


Gene profile

Gene name: DPM1
Reference locus (S288C): YPR183W
Gene biotype: protein_coding

Description: Dolichyl-phosphate beta-d-mannosyltransferase; Dolichol-phosphate mannosyltransferase; Dolichol phosphate mannose (Dol-P-Man) synthase of ER membrane; catalyzes formation of Dol-P-Man from Dol-P and GDP-Man; required for biosynthesis of glycosyl phosphatidylinositol (GPI) membrane anchor, as well as O-mannosylation and protein N- and O-linked glycosylation; human homolog DPM1 can complement yeast mutant strains

Top 10 interactors (score): SEC59 (0.997); PSA1 (0.996); ALG7 (0.995); SAC1 (0.994); CAX4 (0.99); ALG1 (0.988); GPI14 (0.98); RER2 (0.979); ALG3 (0.968); GPI10 (0.963); SEC61 (0.961); SEC53 (0.961); ALG5 (0.95); GPI18 (0.94); SRT1 (0.938); ALG6 (0.937); ERG20 (0.917); SPT14 (0.907); ALG14 (0.906); PGK1 (0.905)

Homologues (species, bitscore): DPM1 (Homo sapiens, 114.0); Dpm1 (Mus musculus, 114.4); dpm1 (Danio rerio, 107.5); dpm1 (Xenopus tropicalis, 107.5); CG10166 (Drosophila melanogaster, 104.8); dpm-1 (Caenorhabditis elegans, 105.1); DPMS1 (Arabidopsis thaliana, 105.1)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005310.1:855030-855833:+ gene-YPR183W_AKU4011 rna-NM_001184280.1_AKU4011 cds-NP_015509.1_AKU4011 98.8 100.0 Verified 1 1 1 True True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000091.1:41876-42679:- gene-YPR183W_BG1 rna-NM_001184280.1_BG1 cds-NP_015509.1_BG1 100.0 100.0 Verified 1 1 1 True True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005518.1:936311-937114:+ gene-YPR183W_Bruggeman rna-NM_001184280.1_Bruggeman cds-NP_015509.1_Bruggeman 99.2 100.0 Verified 1 1 1 True True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005534.1:978371-979174:+ gene-YPR183W_CAT1 rna-NM_001184280.1_CAT1 cds-NP_015509.1_CAT1 100.0 100.0 Verified 1 1 1 True True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005374.1:859831-860634:+ gene-YPR183W_CBS1585 rna-NM_001184280.1_CBS1585 cds-NP_015509.1_CBS1585 98.7 100.0 Verified 1 1 1 True True False False False
CBS436 GCA_001738355.1 Sake Asia CM005358.1:873377-874180:+ gene-YPR183W_CBS436 rna-NM_001184280.1_CBS436 cds-NP_015509.1_CBS436 100.0 100.0 Mismatch 1 1 1 True True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005342.1:861615-862418:+ gene-YPR183W_CBS6412 rna-NM_001184280.1_CBS6412 cds-NP_015509.1_CBS6412 98.8 100.0 Mismatch 1 1 1 True True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005326.1:856759-857562:+ gene-YPR183W_CBS6413 rna-NM_001184280.1_CBS6413 cds-NP_015509.1_CBS6413 98.7 100.0 Verified 1 1 1 True True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001537.1:900831-901634:+ gene-YPR183W_CENPK1137D rna-NM_001184280.1_CENPK1137D cds-NP_015509.1_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005486.1:1176782-1177585:+ gene-YPR183W_EthanolRed rna-NM_001184280.1_EthanolRed cds-NP_015509.1_EthanolRed 99.1 100.0 Verified 1 1 1 True True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005550.1:856855-857658:+ gene-YPR183W_FaliES1 rna-NM_001184280.1_FaliES1 cds-NP_015509.1_FaliES1 99.1 100.0 Verified 1 1 1 True True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000081.1:44162-44965:+ gene-YPR183W_JAY291 rna-NM_001184280.1_JAY291 cds-NP_015509.1_JAY291 100.0 100.0 Verified 1 1 1 True True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005422.1:903546-904349:+ gene-YPR183W_MUCL30387 rna-NM_001184280.1_MUCL30387 cds-NP_015509.1_MUCL30387 99.1 100.0 Verified 1 1 1 True True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005454.1:877675-878478:+ gene-YPR183W_MUCL30388 rna-NM_001184280.1_MUCL30388 cds-NP_015509.1_MUCL30388 99.5 100.0 Verified 1 1 1 True True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005294.1:852031-852834:+ gene-YPR183W_MUCL39482 rna-NM_001184280.1_MUCL39482 cds-NP_015509.1_MUCL39482 98.7 100.0 Verified 1 1 1 True True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005438.1:916504-917307:+ gene-YPR183W_MUCL42920 rna-NM_001184280.1_MUCL42920 cds-NP_015509.1_MUCL42920 99.3 100.0 Verified 1 1 1 True True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011825.1:900738-901541:+ gene-YPR183W_NCIM3186 rna-NM_001184280.1_NCIM3186 cds-NP_015509.1_NCIM3186 98.3 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005278.1:860393-861196:+ gene-YPR183W_NCYC1407 rna-NM_001184280.1_NCYC1407 cds-NP_015509.1_NCYC1407 98.7 100.0 Verified 1 1 1 True True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994155.1:872686-873489:+ gene-YPR183W_PE2H3 rna-NM_001184280.1_PE2H3 cds-NP_015509.1_PE2H3 100.0 100.0 Verified 1 1 1 True True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999887.1:872334-873137:+ gene-YPR183W_PE2H4 rna-NM_001184280.1_PE2H4 cds-NP_015509.1_PE2H4 100.0 100.0 Verified 1 1 1 True True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001148.4:900755-901558:+ gene-YPR183W_S288C rna-NM_001184280.1_S288C cds-NP_015509.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000060.1:24252-25055:- gene-YPR183W_SA1 rna-NM_001184280.1_SA1 cds-NP_015509.1_SA1 98.8 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005502.1:856543-857346:+ gene-YPR183W_ThermosaccDry rna-NM_001184280.1_ThermosaccDry cds-NP_015509.1_ThermosaccDry 99.1 100.0 Verified 1 1 1 True True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005470.1:884341-885144:+ gene-YPR183W_VR1 rna-NM_001184280.1_VR1 cds-NP_015509.1_VR1 100.0 100.0 Verified 1 1 1 True True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000033.1:859089-859892:+ gene-YPR183W_ZTW1 rna-NM_001184280.1_ZTW1 cds-NP_015509.1_ZTW1 99.1 100.0 Verified 1 1 1 True True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047502.1:861164-861967:+ gene-YPR183W_Sparadoxus rna-NM_001184280.1_Sparadoxus cds-NP_015509.1_Sparadoxus 93.4 100.0 Verified 1 1 1 False True False False False

Additional files