Gene name: DPH1
Reference locus (S288C): YIL103W
Gene biotype: protein_coding
Description: 2-(3-amino-3-carboxypropyl)histidine synthase subunit 1; Protein required for synthesis of diphthamide; required along with Dph2p, Kti11p, Jjj3p, and Dph5p; diphthamide is a modified histidine residue of translation elongation factor 2 (Eft1p or Eft2p); may act in a complex with Dph2p and Kti11p
Top 10 interactors (score): DPH2 (0.999); KTI11 (0.999); DPH5 (0.999); DPH6 (0.992); RRT2 (0.991); EFT2 (0.985); JJJ3 (0.973); EFT1 (0.973); ELP2 (0.945); ELP3 (0.86); ATS1 (0.843); DIM1 (0.822); DSK2 (0.813); CIC1 (0.801); UTP25 (0.788); HMF1 (0.778); DBP8 (0.776); RIX1 (0.764); ROK1 (0.763); NMD3 (0.761)
Homologues (species, bitscore): DPH1 (Homo sapiens, 419.5); Dph1 (Mus musculus, 422.9); dph1 (Danio rerio, 433.3); DPH1 (Xenopus tropicalis, 314.7); CG11652 (Drosophila melanogaster, 394.8); dph-1 (Caenorhabditis elegans, 414.8); AT5G62030 (Arabidopsis thaliana, 353.2)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005303.1:173217-174494:+ | gene-YIL103W_AKU4011 | rna-NM_001179451.1_AKU4011 | cds-NP_012163.1_AKU4011 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000164.1:36161-37438:+ | gene-YIL103W_BG1 | rna-NM_001179451.1_BG1 | cds-NP_012163.1_BG1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005511.1:177852-179129:+ | gene-YIL103W_Bruggeman | rna-NM_001179451.1_Bruggeman | cds-NP_012163.1_Bruggeman | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005527.1:169903-171180:+ | gene-YIL103W_CAT1 | rna-NM_001179451.1_CAT1 | cds-NP_012163.1_CAT1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005367.1:173473-174750:+ | gene-YIL103W_CBS1585 | rna-NM_001179451.1_CBS1585 | cds-NP_012163.1_CBS1585 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005351.1:164399-165676:+ | gene-YIL103W_CBS436 | rna-NM_001179451.1_CBS436 | cds-NP_012163.1_CBS436 | 99.9 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005335.1:170853-172130:+ | gene-YIL103W_CBS6412 | rna-NM_001179451.1_CBS6412 | cds-NP_012163.1_CBS6412 | 99.2 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005319.1:164506-165783:+ | gene-YIL103W_CBS6413 | rna-NM_001179451.1_CBS6413 | cds-NP_012163.1_CBS6413 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001530.1:163464-164741:+ | gene-YIL103W_CENPK1137D | rna-NM_001179451.1_CENPK1137D | cds-NP_012163.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005479.1:158439-159716:+ | gene-YIL103W_EthanolRed | rna-NM_001179451.1_EthanolRed | cds-NP_012163.1_EthanolRed | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005543.1:174434-175711:+ | gene-YIL103W_FaliES1 | rna-NM_001179451.1_FaliES1 | cds-NP_012163.1_FaliES1 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000025.1:52822-54099:- | gene-YIL103W_JAY291 | rna-NM_001179451.1_JAY291 | cds-NP_012163.1_JAY291 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005415.1:174689-175966:+ | gene-YIL103W_MUCL30387 | rna-NM_001179451.1_MUCL30387 | cds-NP_012163.1_MUCL30387 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005447.1:173431-174708:+ | gene-YIL103W_MUCL30388 | rna-NM_001179451.1_MUCL30388 | cds-NP_012163.1_MUCL30388 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005287.1:174319-175596:+ | gene-YIL103W_MUCL39482 | rna-NM_001179451.1_MUCL39482 | cds-NP_012163.1_MUCL39482 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005431.1:177572-178849:+ | gene-YIL103W_MUCL42920 | rna-NM_001179451.1_MUCL42920 | cds-NP_012163.1_MUCL42920 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011818.1:171751-173028:+ | gene-YIL103W_NCIM3186 | rna-NM_001179451.1_NCIM3186 | cds-NP_012163.1_NCIM3186 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005271.1:178362-179639:+ | gene-YIL103W_NCYC1407 | rna-NM_001179451.1_NCYC1407 | cds-NP_012163.1_NCYC1407 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994148.1:172860-174137:+ | gene-YIL103W_PE2H3 | rna-NM_001179451.1_PE2H3 | cds-NP_012163.1_PE2H3 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999880.1:166895-168172:+ | gene-YIL103W_PE2H4 | rna-NM_001179451.1_PE2H4 | cds-NP_012163.1_PE2H4 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001141.2:171751-173028:+ | gene-YIL103W_S288C | rna-NM_001179451.1_S288C | cds-NP_012163.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000058.1:10352-11629:- | gene-YIL103W_SA1 | rna-NM_001179451.1_SA1 | cds-NP_012163.1_SA1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005495.1:173103-174380:+ | gene-YIL103W_ThermosaccDry | rna-NM_001179451.1_ThermosaccDry | cds-NP_012163.1_ThermosaccDry | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005463.1:170007-171284:+ | gene-YIL103W_VR1 | rna-NM_001179451.1_VR1 | cds-NP_012163.1_VR1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000019.1:148036-149313:+ | gene-YIL103W_ZTW1 | rna-NM_001179451.1_ZTW1 | cds-NP_012163.1_ZTW1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047495.1:165867-167144:+ | gene-YIL103W_Sparadoxus | rna-NM_001179451.1_Sparadoxus | cds-NP_012163.1_Sparadoxus | 91.4 | 100.0 | Verified | 1 | 1 | 0 | False | False | False | True | False |